Term
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Definition
semi solid dosage forms intended for topical application |
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Term
use of unmedicated ointments |
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Definition
physical effects: protectants, emollients, or lubricants
can also be vehicles for medicated ointments |
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Term
four classes of ointment bases |
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Definition
- hydrocarbon bases
- absorption bases
- water removable bases
- water soluble bases
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Term
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Definition
- provide emollient effect
- protect against the escape of moisture
- occlusive dressing
- remain on skin for long periods without drying out
- contain oleaginous ingredients
- water - immiscible , difficult to wash off
examples: petrolatum, white petrolatum, white ointment, yellow ointment
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Term
petrolatum, white petrolatum, white and yellow ointment |
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Definition
examples of hydrocarbon bases |
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Term
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Definition
- water absorbing or emulsifying property
- can absorb reasonable amounts of water or aqueous solutions without losing consistency
- AKA emulsifiable ointment bases
- dont provide occlusion provided by hydrocarbon bases
- not easily water washable, external phase is oleaginous
- useful when small volumes of aqueous solutions need to be incorporated into hydrocarbon bases
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Term
two types of absorption bases |
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Definition
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Term
anhydrous absorption base |
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Definition
permit incorporation of aq solutions resulting in formula of water in oil emulsion |
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Term
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Definition
- contain water
- water in oil emulsion. also called emulsion bases. permit incorporation of additional quantities of water but only accept limited amounts of water because they already contain it.
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Term
hydrophilic petrolatum USP, polysorb, aquaphor |
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Definition
anhydrous absorption bases |
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Term
hydrous lanolin, cold cream, nivea, eucerin |
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Definition
hydrous absorption bases, aka emulsion bases |
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Term
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Definition
oil in water emulsions
water washable: can be readily washed from skin or clothing with water.
water is external phase so these bases may be diluted with water
ex: hydrophilic ointment |
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Term
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Definition
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Term
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Definition
"greaseless ointment bases"
contain water soluble constituents only.
ex: polyethylene glycol ointment |
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Term
polyethylene glycol ointment |
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Definition
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Term
what type of emulsion is formed when water is added to aquaphor ? |
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Definition
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Term
transdermal drug delivery systems (TDDS) |
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Definition
dermatological preparations for systemic effect |
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Term
locally acting topical agents that have limited chemical or pharmacological activity have a ________ basis of action |
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Definition
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Term
examples that have a physical basis of action (locally acting) |
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Definition
protectives, adsorbents, demulcents, emollients, cleansing agents |
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Term
topical agents with a general CHEMICAL reactivity include |
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Definition
astringents, irritants, rubefacients, vesicants, sclerosing agents, caustics, escharotics, and keratolytic agents |
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Term
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Definition
technique used if the substance to be incorporated into a vehicle is a powder.
the technique uses an intervening liquid in which the powder is insoluble.
the process of grinding a solid between hard surfaces in the presence of a liquid in which the solid is not soluble until it has been reduced to a fine almost impalpable material. |
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Term
levigating agent can also be called |
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Definition
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Term
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Definition
the intervening liquid in which the powder to be incorporated into a vehcile is insoluble |
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Term
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Definition
contain a larger concentration of solids which can be dispersed into the vehicle without the aid of a levigating agent |
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Term
levigating agent + paste is a no no because... |
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Definition
levigating agent can soften the paste and make it look like an ointment |
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Term
example of levigating agent in pastes that call for one |
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Definition
use a little bit of the base ! |
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Term
most frequently used levigating agents |
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Definition
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Term
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Definition
levigating agent used for ointment bases in which oils are the external phase |
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Term
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Definition
levigating agent used for ointment bases in which water is the external phase |
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Term
another name for zinc oxide paste |
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Definition
Lassar's Zinc oxide paste |
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Definition
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Definition
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