Term
Hyperacute Bacterial Connjunctivitis etiologies and signs and symptoms |
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Definition
Nisseria gonorrhea, Nnisseriae, Miningiditis, Staph, Strep, Hameophilus, Moraxella; You will a lot of purency, chemosis, lids are involved; corneal involvement, perforation of the globe through the cornea, PAINFULL |
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Term
Nisseria gonorrhea (hyperactue conjunctivitis) |
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Definition
Common in neonates; Sexually active adolescents and young adults; Starts unilateral; |
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Term
Nisseriae Meningiditis (hyperacute conjunctivitis) |
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Definition
common in children; associated with systemic meningococcal infections |
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Term
1st Line of Therapy for Hyperacute bacterial Conjunctivitis (drug of choice in adults) |
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Definition
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Term
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Definition
1st line of therapy for hyperacute bacterial conjunctivitis; 3rd generation; DOC in adults; IV IM administrated; Bactericidial action; causes a defective peptiodglycan, inhibits cell membrane enzyme (alters permeability, inhibits protein synthesis; You don’t want to exceed 125 mg in children because of it’s toxicity; |
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Term
Ceftriaxone Kinetics and Adverse Effects |
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Definition
1. a single 0.5 g reconstituted to 350 mg/mL produces a serum concentration of approximately 38 ug/mL. 2. Main excretion in the urine dosage adjustment required for renal problems. Adverse Effects |
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Term
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Definition
Treatment for Hyperacute Bacterial Connjunctivitis, 3rd generation; Oral adjuct therapy; Bactericidal action; causes a defective peptidoglycan, inhibits cell membrane enzyme (alters permeability), inhibits protein synthesis; Kinetics – about 40-50% absorbed whether administered with or without food, but time to maximal absorption is slightly delayed when administered with food. 200 mg dose produces 3 ug/mL. Main excretion in the urine (dosage adjustment necessary) |
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Term
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Definition
Hypersensitivity in the for of rash, urticaria, angioedema, pruritus (itch); 10-15% cross allergenicty penicillin; Nephrotoxicty; Diarrhea, abdominal flatulence, dyspepsia; pseudomembranous colitis |
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Term
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Definition
Used as topical therapy for Hyperacute Bacterial Conjunctivitis; |
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Term
Alternative systemic Therapy For Hyperactue Bacterial Conjunctivitis |
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Definition
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Term
Aqueous Penicillin G (5MIU vials) (IV) |
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Definition
Alternative Treatment for Hyperacute Bacterial Conjunctivitis: Bactericidal action, binds to peniciliin binding protein to inhibit transpeption; Forms weak cell wall causing lysis; Also causes the production of autolysins; Adminstered IV; used against: Staphylococcus, Streptococcus, Neisseriaes, Susceptible to penicillinase; Kinetics – excretion is urinary, dosage adjustment necessary in patient with low creatinine clearance |
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Term
Treatment Drugs of Hyperacute Bacterial Conjunctivitis |
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Definition
Ceftriaxon (DOC), Cefixime, Fluoroquinolone |
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