Term
RBE (Relative biologic effectiveness) |
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Definition
relative capabilities of radiation with differing LETs to produce a particular biologic reaction |
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Definition
radiation interacts with DNA macromolecule, energy transferred could rupture one of its chemical bond |
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Definition
loss or change of a base on DNA chain |
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Term
Effects of Irradiation on entire cell |
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Definition
Instant death, reproductive death, apoptosis, mitotic death, miotic death, interference with function |
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Term
Linear energy transfer (LET) |
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Definition
average energy deposited per unit of track |
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Definition
radiation dose required to cause particular biologic response of cells or organisms in an oxygen deprived environment to the radiation dose required to cause identical response under normal oxygenated conditions |
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Term
Two types of chromosome anomalies that have been observed at metaphase |
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Definition
Chromosome aberrations, chromatid aberrations |
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Term
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Definition
breaks rejoin in their original configuration with no visible damage |
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Term
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Definition
Part of chromosome or chromatid is lost at next cell division |
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Definition
grossly misshapen chromosome may be produced |
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Definition
classic method of displaying the sensitivity of a particular type of cell to radiation |
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Definition
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Definition
ionizing radiation adversely affects blood cells by depressing number of cells in peripheral circulation |
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Term
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Definition
initiate blood clotting and prevent hemorrhage |
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Term
Law of Bergonic and Tribondeau |
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Definition
most pronounced radiation effects occur in cells with the least maturity nd specialization, the greatest reproductive activity, longest mitotic phases |
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Term
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Definition
radiation damage resulting from discrete and random events |
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Term
Direct Action Characteristics |
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Definition
DNA, RNA, Proteins, Enzymes |
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Term
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Definition
streams of particles called photos, has no mass and no charge |
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Definition
double strand break in same rung of DNA ladder like structure |
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Definition
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