Term
What is the function of the Lymphatic System |
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Definition
To return fluid leaked out in the intstitial spaces back to the blood stream transport dietary lipids- blood only absorbs carbs and protiens - fats go into lymph Lymphatic organs house lymphocytes Generate an immune response and increase the lymphocyte population
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Term
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Definition
Cervical region - neck Axillary region - arms Groinal region - legs Everywhere that an appendage is attached |
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Definition
Lymph a misxture of interstitial fluid, solutes and sometimes forign material to the blood stream |
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Term
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Definition
Capillaries Vessels Trunks Ducts
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Term
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Definition
Special types of lymphatic capillaries They pickup interstitial fluid, dietary lipids and lipid soluable vitamins GI Lymph is called Chyle
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Term
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Definition
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Term
Where are there no lymph capillaries? (3) |
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Definition
Red bone marrow CNS Avascular tissue
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Term
what is the structure of Lymphatic Vessels? |
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Definition
Resemble small veins have 3 tunics Valves
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Term
What would a blockage in the lympatic system cause? |
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Definition
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Term
where are the lymphatic ducts? What regions of the body to they drain? |
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Definition
Right Lympatic duct - drains upper R. quadrant Thoracic - L quadrant - entire lower body Cisterna Chyli - from small intestine
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Term
Name the 4 Lymphatic cells |
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Definition
Macrophages - monocytes that have migrated from the blood stream Nurse cells - epithelial cells that secrete thymic hormone Dendrite cells - Capture antigens and present them to other lymphatic cells Lymphocytes - B lymphocytes, T lymphocytes and NK cells
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Term
What are the two main types of T Lymphocytes |
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Definition
Helper - Supervisors - initiate and oversee immune response - present antigens to other cells and secrete cytokines Cytotoxic - kill by either secreting substances that break down the invading cell membrane or by triggering cell death.
Two subsets - Memory cells Suppressor cells |
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Term
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Definition
Respond to one antigen - produce immunoglobulins - Antibodies Cannot be activated until a helper T cell presents and antigen Once activated creates plasma cells or memory B lymphocytes
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Term
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Definition
- Natural Killer Cells
- Not Specific
- Can respond to multiple antigens
- Kill a wide variety of infected cells incl. some cancer cells
- determins that cell is growing too fast - kills it
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Term
why would the production of antibodies aid in the immune response? |
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Definition
- Antibodies bind to Antigens
- they immobilize, neutrilize and tag their targets
- This attracts the T-cells which then destroy the antibody covered cell
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Term
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Definition
- Process of lymphocyte development and maturation
- Both T and B cells orginate in the bone marrow
- B cells and NK cells mature in bone marrow
- T cells mature in theThymus
- Thymopoietin and thymosins - hormone that helps them mature
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Term
What are the two Lympatic Structures? |
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Definition
- Lymphatic Nodules
- Lymphatic Organs
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Term
What do Lymphatic Nodules do? |
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Definition
- Oval clusters of Lympatic cells
- Some Extra cellular Matrix
- NOT surrounded by connective tissue capsule
- Contain proliferating B-lymphocytes and some macrophages
- Filter and attach antigens
- MALT - Mucosa Associated Lymphoid Tissue
- e.g. Tonsils
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Term
What is MALT? Where is it found? |
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Definition
- Mucosa Associated Lymphoid tissue
- Lymphatic Nodules
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Term
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Definition
- Lymphatic cells
- Extra cellular matrix
- Completely surrounded by a connective tissue capsule.
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Term
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Definition
- Large in infants and young children
- Each Lobe contains a cortex and medulla
- Cortex - immature T-cells
- Nurse cells
- Some Macrophages
- Medulla contains
- epithelial cells
- Mature T - Cells
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Term
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Definition
- Outer region - T-Cells
- Inner germinal center
- Proliferating B-Cells
- Macrophages
- Function -
- filter antigens from lymph
- Initiate immune responses
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Term
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Definition
- Largest Lymphatic organ
- White Pulp
- Contains Lymphatic cells
- Intiates and immune response when antigens are found
- Red Pulp
- Functions as a blood reservoir
- Macrophages phagocytize bacteria and carry out hemolysis
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