Magnesium Sulfate

:) 

Classification:        

 Electrolyte

Antidysrhythmic

Anticonvulsant

Actions:                 

Essential for sodium/potassium/ATP pumps

Decreases acetylcholine in motor nerve terminals

Produces neuromuscular blockade in CNS

Calcium channel blocker

Indications:            

Polymorphic Ventricular Tachycardia

(Torsades de Pointes)

Seizures associated with eclampsia

Bronchospasm

Contraindications: 

Shock

Heart Blocks

Hypersensitivity

Adverse Effects:

Cardiovascular

bradycardia

hypotension

heart blocks

Neurological

drowsiness

Gastrointestinal

nausea / vomit

Respiratory

depression

Administration:                  

Torsades de Pointes / Bronchospasm    

1-2 gm IVPB in 50-100 ml NS, given over 5 minutes.

 Seizures        

2-4 g IV/IO given over 2-3 minutes.

Pediatrics:              

 Not used in prehospital setting.

Onset: 

Duration:           

Onset:                         3-5 minutes

Duration:                   30 minutes

Precautions:           

Use with caution in patients with impaired renal function.

Administer Magnesium slowly to minimize adverse effects.

Use calcium chloride as an antidote if serious side effects

occur.