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MCB 63 midterm
Coding of Sensory Information
24
Biology
Not Applicable
07/20/2007

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Term
What information is processed by the dorsal column pathway?
Definition
Translation of epicritic touch or two-point discrimination -> ability to recognize touch and distinguish multiple stimuli that are close to one another
Vibration or kinesthetic sense -> epicritic sensation stops shortly after contact with stimulus; kinesthetic sense detects movement, which indicates that the stimulus is still there
Limb proprioception -> works with cerebellum to locate the body’s limbs in 3D space (more localized activity)
Term
dorsal column pathway [image]
Definition
[image]
Term
What info is processed by the Spinothalamic or Anterolateral Pathway?
Definition
•picks up pain in the form of tissue damage, temperature (often associated with tissue damage), light touch (tickling and itching)
Term
Describe the pathway of the anteroventral or spinothalamic pathway [image]
Definition
information synapses in Lamina II (Substantia Gelatinosa) •pain travels relatively slowly: pain and some temperature are Adelta fibers, temperature and light touch are C fibers
[image]
Term
What is a lesion and what does it do?
Definition
•lesion is tissue damage -> causes secretion of substances: bradykinin (makes pain worse), serotonin, prostaglandin, K+ -> Substance P (for Pain) produces a mast cell which produces histamines -> helps tissue to destroy irritant; heightens pain sensation
Term
Describe the anatomy of the spinocerebellar pathway. [image]
Definition
•information synapses in the outer edges of the spinal cord •The tract does not cross; the information from proprioceptors is received on the ippsilateral side of the cortex (in contrast to epicritic touch and pain pathways) [image]
Term
What info does the spinocerebellar pathway convey?
Definition
•body position sense (where your body is in space)
•responsible for unconscious proprioception – sensation of where a limb is sitting in space
•whole component of the body (less localized than limb proprioception)
Term
What are symptoms of cerebellar disease?
Definition
dysmetria – hand overshoots mark
adiadochokinesia – difficulty performing rapidly alternating movements
Term
Describe the anatomy of the corticospinal tract[image]
Definition
•Pyramidal cells – large neurons in the primary motor area of the cerebral cortex with a triangular shape -> huge axons extend from cortex to the spinal cord
•Information synapses in Lamina IX (main motor region of the spinal cord) where anterior horn cells are found
[image]
Term
What does the corticospinal tract control?
Definition
•Voluntary control of movement
Term
What happpens when you damage upper motor neurons?
Definition
•Damage to upper motor neurons -> initial flaccid paralysis (neurons have no idea what to do), then spasticity/rigid paralysis (reflexes take over)
•The difference between spinal cord damage and spinal nerve damage; upper motor neuron lesion v. lower motor neuron lesion
Term
Describe the function and anatomy of the rubrospinal tract.
Definition
•Rubro = red -> red nucleus gets information from cerebellum and cortex
•Mainly controls fine motor movement (hands, feet, face)
Term
Describe the extrapyramidal tracts
Definition
•Ventromedial pathways: (pontine reticulospinal, vestibulospinal, meduallary reticulospinal, tectospinal)
•Get information from basal ganglia
•Coordinate movements
•Control larger muscle groups -> get body in position so the fine motor functions can do what they need to do
Term
Herpes Zoster
Definition
viral infection of dorsal root neurons and spinal nerves. almost everyone has it, but remains dormant until immune system is compromised occurs in particular dorsal roots --> sensitive corresponding dermatomes
Term
phrenic nerve
Definition
part of the cervical plexus; innervates diaphragm
Term
What happens when there is damage to uppper motor neurons vs. lower motor neurons?
Definition
o Damage to upper motor neurons --> flaccid paralysis followed by rigid paralysis (spasticity)
o damage to lower motor neurons --> flaccid paralysis
Term
arcuate fibers
Definition
part of the dorsal columns pathway that crosses in the brainstem
Term
medial lemniscus
Definition
part of the dorsal columns pathway that travels through the midbrain
Term
anterior white commissure
Definition
decussation of the spinothalamic pathway in the spinal cord
Term
Rubrospinal tract
Definition
deals with control of fine motor movement in the hands, feet, and face
Term
ventromedial pathways
Definition
controls large muscle groups -> gets them ready to do what fine motor functions need to do get information from basal ganglia -> responsible for programming and execution of movement
Term
[image]
Definition
[image]
Term
anterior white commissure
Definition
•anterior white commissure = spinothalamic version of arcuate fibers the difference is that this crossing occurs in the spinal cord rather than the brain stem as is the case for the dorsal column pathway
Term
[image]
Definition
[image]
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