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MCB 63
Midterm
48
Biology
Not Applicable
07/20/2007

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Cards

Term
Sodium-Potassium Pumps
Definition
pumps located in the cell membrane that monitor [Na+] and [K+] by pulling Na+ out of the cell body once it gets in
Term
Resting potential
Definition
usually -90 to -70 mV ; everything is cool inside the cell
Term
Action potential
Definition
change in voltage across the cell:
Na+ slips in and opens enough doors to allow a flux of Na+ ions --> the cell becomes more positive; K+ begins to exit the cell, making it even more positive
Term
Axon hillock/nodes of Ranvier
Definition
areas where action potential is rejuvenated
Term
oligodendroglial cells
Definition
neuroglia that create myelin sheath
Term
saltatory conduction
Definition
information jumping from one node to the next
Term
MS
Definition
multiple sclerosis - death of myelin in random spots --> no signals to and from the brain
Term
ALS
Definition
Amyotrophic lateral sclerosis - pattern loss of fine motor control, followed by loss of gross motor control --> victims functionally become trapped inside their own bodies
Term
synaptic cleft
Definition
space between pre- and post-synaptic elements, found in mammals
Term
GABA
Definition
gamma-aminobutyric acid, a major inhibitory neurotransmitter
Term
endoderm
Definition
future internal organs
Term
mesoderm
Definition
future structural components (bone, connective tissue, etc.)
Term
ectoderm
Definition
future skin and nervous system
Term
spina bifida
Definition
deformity of the lower spinal cord, caused when the posterior neuropore does not seal
Term
spina bifida
Definition
deformity of the lower spinal cord, caused when the posterior neuropore does not seal
Term
anencephaly
Definition
cerebral cortex, covering skull and skin do not form; caused when the anterior neuropore does not seal
Term
notochord
Definition
tissue that secretes growth hormone and stimulates cell growth in the ectoderm
Term
myelencephalon
Definition
secondary brain vesicle; future medulla oblongata
Term
metencephalon
Definition
cerebellum and pons
Term
mesencephalon
Definition
midbrain (includes superior and inferior colliculi)
Term
diencephalon
Definition
thalamus and hypothalamus
Term
telencephalon
Definition
cerebral cortex, hippocampus, basal ganglia
Term
Herpes Zoster
Definition
viral infection of dorsal root neurons and spinal nerves. almost everyone has it, but remains dormant until immune system is compromised

occurs in particular dorsal roots --> sensitive corresponding dermatomes
Term
phrenic nerve
Definition
part of the cervical plexus; innervates diaphragm
Term
dorsal columns pathway
Definition
ascending pathway that deals with epicritic touch, kinesthetic sense, and limb proprioception

crosses in the medulla
Term
spinothalamic pathway
Definition
aka anterolateral pathway

descending pathway responsible for pain associated with tissue damage, temperature, tickling and itching

crosses immediately in the spinal cord

synapses in Lamina II
Term
arcuate fibers
Definition
part of the dorsal columns pathway that crosses in the brainstem
Term
medial lemniscus
Definition
part of the dorsal columns pathway that travels through the midbrain
Term
neurosyphilis
Definition
attacks myelin of dorsal columns --> individuals lose touch sensation
Term
anterior white commissure
Definition
decussation of the spinothalamic pathway in the spinal cord
Term
spinocerebellar pathway
Definition
responsible for unconscious proprioception (where your body is in space)

does not cross; information is received on the ipsilateral side in the thalamus

synapses in Lamina IX where it tries to stimulate anterior horn cells to direct muscles

damage to upper motor neurons-> flaccid paralysis followed by rigid paralysis (spasticity)

damage to lower motor neurons -> flaccid paralysis
Term
corticospinal pathway
Definition
cortex -> spinal cord -> muscles

responsible for voluntary control of movement
Term
Rubrospinal tract
Definition
deals with control of fine motor movement in the hands, feet, and face
Term
ventromedial pathways
Definition
controls large muscle groups -> gets them ready to do what fine motor functions need to do

get information from basal ganglia -> responsible for programming and execution of movement
Term
frontal lobe
Definition
planning ahead, prediction, programming individual needs;speech and motor functions
Term
temporal lobe
Definition
hearing, memory processing; possibly integration of sensory functions
Term
parietal lobe
Definition
pain, temperature, touch, pressure

includes primary sensory area
Term
occipital lobe
Definition
visual information processing
Term
medualla oblongata
Definition
controls vital functions such as respiration and heart rate
Term
colliculi
Definition
part of the midbrain that coordinates visual and auditory reflexes
Term
thalamus
Definition
integration and processing of sensory input (except smell) -> "sensory gateway to the cerebral hemispheres"
Term
hypothalamus
Definition
controls endocrine system, VNS, respiratory and heart rate, appetite, etc.
Term
basal ganglia
Definition
programming and execution of movement ->fine motor coordination (works with cerebellum, thalamus, colliculi)

assists in emotional response, learning

diseases -> Parkinson's, Tourrette's
Term
limbic lobe
Definition
sexual and emotional aspects of behavior; processing of memory
Term
midbrain
Definition
automatic (reflex) patterns associated with visual and auditory systems
Term
pons
Definition
relay between cerebral hemispheres and the cerebellum
Term
cerebellum
Definition
muscle coordination and balance involved in actions such as writing and walking
Term
visceral nervous system
Definition
innervation of cardiac muscle, glands, smooth muscles of cavity-containing body organs (viscera)

includes hair raising muscles, blood vessels, parts of the brain and spinal cord
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