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MCMP 305 - April 23rd
Biochemistry - Ashendel
24
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Professional
04/27/2010

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Term
What is the typical recommended micronutrient intake?
Definition
mg or ug/day
Term
What are junk foods?
Definition
Foods with little or no micronutrients
Term
What are fortified junk foods?
Definition
Junk food with added micronutrients
Term
What are the organic micronutrients?
Definition
Fat soluble vitamins: A, D, E, K
Water soluble: B complex, C
Others: choline, lipoamide, carnitine
Term
What are the inorganic micronutrients?
Definition
MINERALS
Macrominerals >1mg/day
Microminerals <1mg/day
Term
What are some issues unique to micronutrition?
Definition
-possible subclinical deficiency
-controversial claims for essentiality of natural products

-overnutrition is NOT a concern
-controversial claims for benefits of higher (optimal) dose
-tissue redistribution under stress makes assay difficult
Term
What does UL stand for?
Definition
Upper limit
Term
What does EAR stand for?
Definition
Estimated average requirement
Term
What does RDA stand for?
Definition
Recommended Daily Allowance
Term
What does AI stand for?
Definition
Average Intake
Term
Who are RDAs designed for?
Definition
healthy people within 2 standard deviations from the mean (not including people w/ infections or metabolic disorders)
-based on minimumss to avoid symptoms of deficiency, not on optimal amounts
Term
Why shouldn't people rely solely on supplements and fortified foods for their diet?
Definition
Some essential micronutrients may not even be known yet, so it is best to include many diverse whole foods in the diet
Term
What form of Vitamin A is an antioxidant?
Definition
Beta-Carotene
Term
What forms of Vitamin A are steroid hormones?
Definition
Retinoic acid (activates gene expression) and Retinol (probably first converted to Retinoic acid)
Term
What is the form of Vitamin A used in the visual cycle?
Definition
Retinal
Term
What is the form of Vitamin A that is used as storage forms?
Definition
Retinyl esters
Term
What form of Vitamin A is used in glycoprotein synthesis?
Definition
Retinyl phosphate - glycosyl donor
Term
Describe the interconvertability of the different forms of Vitamin A.
Definition
-Retinoic acid cannot be reduced to retinal
-Retinol cannot be converted back to carotenoids
-All others are interconvertable
Term
Rhodopsin is in ______ and photopsins are in _________
Definition
Rhodopsin is in rods and photopsins are in cones
Term
Describe the vision cycle
Definition
Rhodopsin (and light in) --> trans-retinal, (nerve impulse and opsin out)--> cis-retinal (and opsin in) --> back to Rhodopsin
Term
What are the most differentiated cells in stratified epithelium?
Definition
secretory or keratinizing cells
Term
Where does keratinization usually occur?
Definition
Skin, mouth, esophagus, and nasopharynx
Term
What happens during Vitamin A deficiency?
Definition
Keratinization occurs in tissues where it normally does not: respiratory tract, GI tract, genitourinary tract, and cornea
Term
What is the basis of Retin A (topical retinol, retinoic acid) treatment of acne?
Definition
direct treatment of tissues with topical retinol or retinoic acid causes metaplasia (less keratinization)
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