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mechanical vent
1st exam
116
Medical
Undergraduate 2
02/14/2011

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Term
Respiratory Failure
Definition
A condition where the resp syst fails to maintain its principle function : adequate oxygenation of arterial blood and removal or elimination of CO2
Term
normal blood gas at Sea Level
Definition
Ph- 7.35 to 7.45
PACO2 35-45 mmhg
HCO3 22-25 meq/l
PaO2 80-100 mmhg

the higher the altitude..the lower the PO2
Term
Chronic RF ABG
Definition
PaO2< 60 mmhg
PaCO2> 50 mmhg
ph 7.35-7.45
HCO3 22-26 mmhg
Term
Compensation in Chronic RF
Definition
1.changes in Resp pattern(v/q)
2.use of accessory muscle
3.hyperventilation-ventilate greater than needed for metabolism
4.circulatory adjustment(to increase O2 transport
5.alteration in blood (collateral circulation) incr HGB
6.Renal compensation (incr HCO3 to correct acid base balance)
7. decr physical activity
Term
Acute RF
Definition
1.Rapid onset
2.No Compensation
3.Inadequate tissue/organ perfusion
4.severe acid base disturbance (PH)
Term
Acute RF ABG's
Definition
PaO2<60mmhg (low)
PaCO2> 50mmhg (high)
PH decr 7.35-7.45 decr acidosis
HCO3 normal
Term
3 types of Respiratory Failure
Definition
1.Ventilatory Failure
2.hypoxemic-hypercarbic RF
3.Hypoxemic RF
Term
Ventilatory Failure
Definition
1 ventilatory fails in the presence of normal lungs.
2.Pure Alveolar hypoventilation ( lungs are normal but simply not breathing
3.Normal AaDO2, less than 10mmhg
Term
Causes of VF
Definition
depressed resp center
1. CNS depressant Drugs
2.Cerebral Tumors
3. Cerebral trauma(resp center in brain not sending signal to diaphragm to work.
Insufficient Chest Wall function
1. Neuromuscular Disease
2. Trauma
3. Kyphoscoliosis
4. obesity/pregnancy
5. Neuromuscular blocking agents
Sleep Apnea
1. central- brain doesnt send out signal to breath
2. obstructive
3. mixed
Term
Hypoxemic-hypercarbic RF
Definition
1. inability to excrete CO2
2. marked V/Q imbalance with airtrapping
3. hypoxemia
4. hypocarbia
Term
hypoxemic-hypercarbic RF causes
Definition
Copd
1. cystic fibrosis- disease of sweat glands and mucous glands
2. Bronchitis(chronic)
3. Asthma
4. Bronchiectasis
5. Emphysema(cant exhale, CO2 buildup)
Term
Hypoxemic RF
Definition
1. inability to oxygenate arterial blood
2. ventilate ok(PaCO2 normal or Incr
3. PaO2 decr, AaDO2 incr
Term
Causes of Hypoxemic RF
Definition
1. Pulmonary Edema
2. Atelectasis
3. Lung injury
4. ARDS
5. Pulmonary Fibrosis
Term
precipitating or exacerbating factors
Definition
1. changes in the TB secretions
2. infections
3. disturbance of TB clearance
4. Drugs
5. inhalation or aspiration of irritants, vomitus or foreign bodies
6. cardiovascular disorders
a. pulm embolism
b. shock
7. mechanical factors
a. pneumothorax
b. pleural effusion
c. abdominal distension/obesity/pregna
8. trauma surgery
9. allergic disorders
a. bronchospasm
10. incr O2 demand
a. fever
b. infection
c. seizure
11. inspiratory muscle fatigue
Term
subcutaneous emphysema
Definition
A collection of air or gas beneath the layers of the skin
Term
compliance
Definition
Distensibility (stretchiness) of the lungs, calculated by the formula vol divided by pressure and expressed as ml/cmh2o
Term
resistance
Definition
opposition to airflow determined by airway diameter and high flow rates, expressed as cmh2o/L/sec
Term
spirometer
Definition
an instrument for measuring lung volumes.
Term
elastic recoil
Definition
the tendency of the lungs to return to a resting state after being inflated
Term
minute volume
Definition
amt of air passing into and out of the lungs in 60 seconds, usually expressed in liters
Term
pneumothorax
Definition
accumulation of air in the pleural space, resulting in collapse of the lung on the affected side.
Term
manometer
Definition
an instrument for measuring the pressure of the liquids or gases
Term
Tidal volume
Definition
amt of gas passing into and out of the lungs in each resp cycle, usually expressed in milliliters
Term
Dead space
Definition
the portions if the resp tract that are ventilated but not perfused by the pulmonary circulation;includes anatomical and alveolar
Term
Pneumopericardium
Definition
presence of gas or air in the sac surrounding the heart which may interfere with the cardiac pumping ability.
Term
Inverse
Definition
An I:E ratio where the inspiratory time is longer that the expiratory time.
Term
Exhalation valve
Definition
a mechanism in a MV through which the patient exhales; this mechanism must close to allow inspiration
Term
Shunt
Definition
the portion of the cardiac output that returns to the left side of the heart without being oxygenated, I:E blood that perfused the lungs but did not participate in gas exchange; includes anatomic capillary
Term
inflation hold
Definition
MV maneuver where a vol of gas in delivered to the pt and kept in the lungs for a preset amt of time before expiration is allowed to occur.
Term
Pneumomediastinum
Definition
Presence of air or gas in the thoracic space containing the heart, trachea, and esophagus; it may interfere with respiration and circulation
Term
Spontaneous Ventilation
Definition
Signal from the brain to the Diaphragm via phrenic nerve(C3,4,5)
Term
MVS Indications
Definition
1. Acute resp failure, acute ventilatory failure, acute respiratory acidosis

2. impending resp failure- can see it coming

3. Apnea ( or absence of adequate ventilation)

4. inadequate oxygenation, not as common
Term
T or F
MV does not cure the disease process
Definition
TRUE
Term
MVS Goal
Definition
maintain adequate cardiopulmonary function with minimal side effects on other body systems
1. to allow pulm syst to recover
2. maintain bronchial hygiene
3. decr myocardial work
4. decr WOB
5. improve gas distribution
6. restore acid/base balance
Term
Parameters of MV
Definition
HX
DX- diagnosis
physical assessment
ABG's
lung mechanics(nip,vc,vt etc.)
prognosis
Term
name 2 types of mechanical ventilation
Definition
1. Negative pressure
2. Positive pressure (use this the most)
Term
Negative Pressure was first used in the 1940's for ______ patients.
Definition
polio
Term
name 3 approaches that apply extrathoracic negative pressure which is trnasmitted through the chest wall to alveolar spaces causing airflow to lungs
Definition
1. iron lung
2. chest cuirass
3. pneumosuit
Term
name some neg pressure cons
Definition
1. large size
2. noisy
3. pt is inaccessible
4. hard to seal
5. not much adjusting possible
6. pooling of blood in the abs(tank shock)
Term
Neg pressure ventilation advantages
Definition
1. easy to use
2. dependable
3. No ETT needed
4. pt can talk, eat, drink
5. fewer physiologic side effects than PPV
Term
whats the pnemobelt do?
Definition
It inflates the bladder pushing the abdominal contents up moving the diaphragm...helping expiration.
can acheive Vt up to 300 ml
its a pt ventilatory assist device
advantage: noninvasive
Term
whats the rocking bed do?
Definition
supports ventilation by rhythmically moving the diaphragm and abdominal contents by rocking bed
Vt up to 500 ml
rates up to 30/min
can cause motion sickness
Term
explain positive pressure ventilation
Definition
important that you must create a pressure gradient for air to flow.
Neg pressure vents create positive pressure by lowering alveolar pressure relative to ambient pressure
Positive Pressure vents create positive pressure by raising pressure outside the mouth higher the alveolar pressure
measuring ventilating pressure in CMH2O
Term
explain positive pressure
Definition
PPV occurs when a system literally blows air into patients lungs...the pressure must be high enough to overcome elastic forces of lung, chest wall and resistance.
Term
T or F
PPV is not natural.
Definition
True
Term
PPV can be invasive and non invasive...give example of both
Definition
invasive- (ETT)
noninvasive- (face mask, nasal mask, mouthpiece and face shield)
Term
PPV pressures are measured at the.....(3)
Definition
1. mouth
2. circuit
3. ventilator
Term
The best place to measure positive pressures is......
Definition
mouth
Term
Baseline pressure is....
Definition
Pressure at end- expiration.
normally 0 cmh20(atmospheric.
can be > 0 cmh2o is PEEP(positive end expiratory pressure) set by operator= intentional=extrinsic

unintentional is intrinsic which is auto peep. ( our fault)if set wrong then can cause barotrauma and airtrapping
Term
Peak Pressure is....
Definition
the highest pressure attained during inspiration(doesnt have to be end pressure)
Term
PIP formula is....
Definition
PIP= PA + Praw
Term
Plateau Pressure is....
Definition
No GAS flow during plateau
pressure during inspiratory hold
1.IS part of T1 because no gas flow during
2. good impression on alveolar pressure, the hold takes away the praw and allow you to measure PA.
PIP= Pplat + Praw
Praw= 5 cmh2o = pressure lost in airways
Pplat= pressure for gas exchange
Term
PIP is usually...
Definition
40 cmh2o
Term
Pplat is usually.....
Definition
26 cmh2o and goes down
Term
Mean pressure is ...
Definition
ave pressure throughout the respiratory cycle. its a funtion of the amount of pressure and duration of pressure. Important in infants and children.
Term
Mean airway pressure is determined by
Definition
pip, eep, RR, I:E ratio(Ti and Te), ventilation mode, inspiratory waveform, flow
Term
T or F
FIO2 effects mean airway pressure
Definition
False
Term
what are the volumes measured for MV
Definition
1. inspired Vt
2. expired Vt
3. minute volume
note: the gas that comes in and the gas that goes out have to be close to equal
Term
T or F according the Mean Airway pressure...if PaO2 goes up then MAP goes up and if MAP goes up then side effects go up
Definition
True
Term
T or F all the airway under the curve is mean airway pressure.
Definition
TRUE
Term
describe Pneumatic power source
Definition
 Use only "compressed gas for power
 50 psi pressure reduced to safe level
 Compressed gas source lost"no ventil"
 2 types
 "pneumatic"
▪ Needle valves, injectors, diaphragms, spring-loaded valves
to control gas flow, timing & volume delivery
 "fluidic"
▪ Uses fluidic principle (Coanda Effect) to control functions
Term
Describe electric power source
Definition
 Operate by "electricity" alone
 Use compressed O2 only to ↑ FIO2 > 0.21
 Gas source lost  vent will ventilate but
_____________________
 Compressors, fans, bellows, solenoids to provide
gas flow
Term
describe combined power source
Definition
 Uses both "electricity and gas" to
operate
 Electricity to control functions
 Compressed gas to provide energy for gas flow
 Lose either  "no ventilation"
Term
List 7 types of drive mechanisms used to generate inspiratory force.
Definition
. Compressor
. Volume displacement or Bellows
. Linear Driven piston
. Rotary Driven Piston
. proportional solenoid valve
. Control panel
. volume controller
. flow controller
Term
whats the difference between single vs double internal circuits
Definition
on single circuit, gas from the source goes directly in one flow to the patient. On Double circuit gas goes from the source causes a secondary mechanism to compress causing a secondary flow that goes to the patient.
Term
describe a mandatory breath
Definition
• = machine (time)-cycled breath
• Initiated by ventilator
• Ended by ventilator
• Vent performs all of the WOB
• = full ventilator supported breath
Term
describe assisted breath
Definition
• Initiated by Patient
• Ended by ventilator
• The only WOB patient does is triggering inspiration,
vent does the rest
• = partial ventilatory supported breath
Term
describe spontaneous breath
Definition
• = patient breath
• Initiated by patient
• Ended by patient
• Patient does all the WOB
• Much like nebulizer blow-by, i.e vent is only providing
humidity, heat, FIO2, EEP
• = no ventilator support
Term
List mechanical ventilator control variables.
Definition
1. volume
2. inspiratory time
3. flow
4. pressure
Term
Discuss the Flow vs insp time relationship
Definition
• flow delivered for a period of time will result in a
volume
VT(L) = flow (L/s) x IT (s)
VT = flow divided by 60 x IT
Term
discuss the flow vs pressure gradient relationship
Definition
• Depends on the difference in pressure between the
power source, ventilator & the pressure in the lungs
• i.e the greater the pressure gradient  the greater the
flow rate that can be achieved
• Clinically important because different vents are capable
of different high-end flow rates
Term
describe the pressure vs lung compliance relationship
Definition
stiff lungs inflated with Vt of 500 would have more pressure in them then stretchy lungs with a vt of 500.
Term
describe the pressure vs volume delivered relationship in lungs
Definition
normal lungs with a vt of 1000 would have more pressure in them then normal lungs with vt of 500
Term
describe the pressure vs airway resistance relationship in lungs
Definition
lungs inflated with vt of 500 that has an airway with lots of secretions would have more pressure in them then lungs with a vt of 500 that has no secretions on the airway
Term
what are 4 things that would cause resistance to gas flow
Definition
1. diameter to the airway
2. bronchospasm
3. secretions
4. edema and swelling
Term
What do phase variables do?
Definition
they are used to change phases of ventilatory cycle
Term
Any breath can be described in detail by answering 4 simple questions
Definition
1. What causes the breath to begin?
2. What happens during inspiration?
3. What causes the breath to end?
4. What occurs during exhalation
Term
Describe Trigger Phase variable
Definition
• Causes vent to begin inspiratory phase
• 3 types:
• Time
• Patient effort
• Negative pressure
• Flow
• Manual
Term
describe Time "trigger"
Definition
• Vent initiates inspiration at an operator-selected time
(w/o regard to Patient effort)
• “Cycle rate”, “BPM”, “Respiratory Rate” controls all set
Total Cycle Time (TCT, TC)
TC = IT + ET
TC=60sec divided by RR
Term
Describe "patient/Neg pressure" triggering
Definition
• Patient effort causes _____________ pressure
• At the negative pressure (Sensitivity) set by the
operator, vent begins inspiration
• Normally set at -1 or -2 cmH2O
Term
Is ventilator more “sensitive” at -5
cmH2O or -1 cmH2O?
Definition
-1 cmh2o
Term
re: patient/neg pressure trigger

time between patient effort and response of ventilator is ?

this is measured in ?
Definition
response time

msec
Term
incr response time is incr on patient
Definition
WOB
Term
reasons why is "flow" triggering is better
Definition
• Base flow & flow sensitivity is preset on most vents
• Flow-triggering greatly reduces the WOB because as
the patient begins the insp effort, gas is available,
instead of having to create neg. pressure & maintain
that pressure until a demand valve opens
(it doesnt have to wait)
Term
describe the settings on "flow" trigger"
Definition
• Newest method
• Set “base flow”
• Continuous flow through circuit
• ~ 10 LPM
• Set “flow sensitivity”
• = how much flow patient must pull from circuit for vent to
begin inspiration
• 1 - 3 LPM
Term
describe " Manual" trigger
Definition
• Some vent have a “Manual Inspiration” button/dial/pad
to initiate an inspiration at the volume/pressure
parameters set
Term
when would you use "manual" trigger?
Definition
1. hyperventilation
2. hyperventilation to decr ICP
Term
name 4 things that cause the ventilator to end inspiration
Definition
1. volume cycling (ML or L)
2. pressure cycling (cmh2o)
3. time cycling (sec)
4. flow cycling (L/M)
Term
describe "volume" cycling
Definition
• Inspiration ends when a preset "volume"
has been delivered to the patient circuit
• If no leaks are present - every breath is the same
volume
• Pressure generated is variable from breath-to-breath
depending on lung characteristics (CL, RAW)
Term
How is ventilator set for this?
Definition
• Set VT (ml) (can set 2 of the 3)
Set flow rate of gas (lpm)
• Setting these parameters sets the TI(inspiratory time)
• = volume-cycled(set), flow-limited ventilation(limited because its set)
. formula used is Vt(L)=flow(l/m)/60 x Ti (know that every breath is the same)
Term
describe Cycling- Time
Definition
• Inspiration ends when a preset Ti
has elapsed
• Every breath is the same TI
• Can be volume-targeted or pressure-targeted (vent. will deliver vol and flow to reach that Pressure)
Term
describe "volume ventilating" using time cycling
Definition
• Set TI (% TC)
Set VT (ml)
• Setting these parameters sets the gas flow rate (lpm)
• = time-cycled, flow-limited ventilation
. important: if vol is set then pressure happens and could vary meaning it can change from breath to breath.
. if you set 2 parameters then the third is automatically set...ex: if you set Ti and vol then flow is automatically set
Term
describe " pressure ventilating" using time cycled
Definition
• Set TI (% TC)
Set Insp Pressure (cmH2O)
• = time-cycled, pressure-limited ventilation
**when you set pressure volume happens and can vary because of lung compliance and airway resistance. you set the ventilator but vol varies with each breath.
. know that time-cycled means that time ends the inspiration
Term
explain "flow" cycling
Definition
• Inspiration ends when " inspiratory flow" drops to a
preset level (lpm)
• Pressure Support mode (PS)
***pressure supported breath is flow cycling***
=flow cycled, pressure- ventilated flow
***pressure set stays the same***
know for example that if inspiratory flow is set like to 25% then terminal flow is set to 25% of peep flow..in other words its set to end 25% of what peep flow was and inspiration varies from breath to breath.
on notes:
• In Pressure Support mode (PS), terminal flow is preset
• Inspiratory pressure level is also set
• Volume delivered is variable from breath-to-breath
depending on lung characteristics (CL, RAW)
• = flow-cycled, pressure-limited ventilation
Term
explain "pressure" cycling
Definition
• Inspiration ends when a preset Presure
has been reached in the patient circuit
• Volume delivered, flow rate of gas & TI are variable
from breath-to-breath depending on lung
characteristics (CL, RAW)
• Bird IPPB machines
• = pressure-cycled ventilation
Term
patient circuit tubing is stretchy/compliant and stretches under pressure trapping volume..how much pressure gets trapped in tubing?
Definition
1-2 cmh2o
Term
whats the tubing compliance formula
Definition
VT= set Vt - (PIP-PEEP x tubing compliance)
Term
T or F

leaks in system are impossible to avoid
Definition
True
Term
what is the "limit" during the inspiratory phase?
Definition
it means that phase is set.
Term
Give 3 reasons a patient does not receive the set volume when volume targeting ventilation.
Definition
1. tubing compressed vol
2. leaks
3. spontaneous breathing
Term
manometer
Definition
1. an instrument for measuring the pressure of liquids or
gases
Term
pneumothorax
Definition
accumulation of air or gas in the pleural space, resulting
in collapse of the lung on the affected side
Term
minute volume
Definition
amount of gas passing into and out of the lungs in 60 seconds, usually expressed in liters
Term
elastic recoil
Definition
the tendency of the lungs to return to a resting state after being inflated
Term
spirometer
Definition
an instrument for measuring lung volumes and capacities
Term
resistance
Definition
opposition to airflow determined by airway diameter and high flow rates, expressed as cmH2O/L/sec
Term
compliance
Definition
distensibility ("stretchiness") of the lungs, calculated by the formula vol ÷ pressure and expressed as ml/cmH2O
Term
subcutaneous emphysema
Definition
a collection of air or gas beneath the layers of the skin
Term
tidal volume
Definition
amount of gas passing into and out of the lungs in each respiratory cycle, usually expressed in milliliters
Term
pneumomediastinum
Definition
presence of air or gas in the thoracic space containing
the heart, trachea, and esophagus; it may interfere with respiration and circulation
Term
inflation hold
Definition
mechanical ventilation maneuver where a volume of gas is delivered to the patient and kept in the lungs for a preset amount of time before expiration is allowed to occur
Term
shunt
Definition
the portion of the cardiac output that returns to the left side of the heart without being oxygenated, i.e. blood that perfused the lungs but did not participate in gas exchange;includes anatomic and capillary
Term
exhalation valve
Definition
a mechanism in a mechanical ventilator through which the patient exhales; this mechanism must close to allow inspiration
Term
inverse
Definition
an I:E ratio where inspiratory time is longer than expiratoy time
Term
pneumopericardium
Definition
presence of gas or air in the sac surrounding the heart which may interfere with cardiac pumping ability
Term
deadspace
Definition
the portions of the respiratory tract that are ventilated but not perfused by pulmonary circulation; includes anatomical and alveolar
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