Term
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Definition
mitochondria
golgi apparatus
ER
nuclear envelope
lysosome
peroxisome |
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Term
|
Definition
nucleolus
ribosomes
microtubules
centrioles/basal bodies
microfilaments
intermediate filaments
inclusions |
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Term
| Characterisics of cell membranes |
|
Definition
separates cells from environment
composed of lipids and proteins
dynamic, active
maintains compositional differences between outside and inside |
|
|
Term
|
Definition
ion pumps and ion channels
hormone receptors
adhesion to ECM
adhesion to other cells |
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Term
| Transport Mechanism-Transmembrane |
|
Definition
1. diffusion (steroids)
2. passive transport through pump (glucose)
3. active transport (energy consuming) |
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Term
|
Definition
-energy consuming process
1. exocytosis (proteolytic enzymes)
2. endocytosis
3. pinocytosis: endocytosis of fluids and solutes |
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Term
|
Definition
1. Most common pediatric genetic disorder in whites (1/3,000)
2. defect in epithelial ion transport
3. affects secretions of exocrine glands
4. viscous mucus, pulmonary infections, pancreatic insufficiency, fatty stool, malnutrition, cirrhosis, intestinal blockage, male infertility |
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|
Term
| Cystic Fibrosis-Molecular Bio |
|
Definition
1.Mutation in CFTR (cystic fibrosis transmembrane conductance regulator) on chrom 7
2. abnormalities in Cl- transport
a. Na and Cl- accumulates in lumen of sweat ducts (salty skin)
b. Cl- cannot pass into lumen of airways--causes increase in Na+ and H20 to be taken into epithelium--viscous mucus |
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Term
|
Definition
1. E-face (external): fewer intramembranous particles
2. P-face (protoplasmic): lots of intramembranous proteins, transducers |
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|
Term
| Membrane Comparmentalization |
|
Definition
1. separates nucleus and cytoplasm
2. allow increased efficiency by grouping related enzymes |
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