Term
| What is most at risk for Legionella? |
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Definition
| The elderly and immunosuppressed |
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Term
| Patholgenesis of Legionella? |
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Definition
1. inhaled 2. Engulfed by macrophage 3. Survives and proliferates in phagosome 4. Infected macrophages secretes chemattractants |
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Term
| Treatment of mycobacterium leprae |
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Definition
T. Leprosy: 1. Dapsone + rifampin for 6 months L. Leprosy: 1. Dapsone + Clofazimine for 2 yrs |
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Term
| Clinical Presentation & diagnosis of Lepromatous leprosy |
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Definition
Grows on Low Temp areas of skin Presents: 1. Inflammation damage at skin, nerves and testes 2. Sensory loss 3. Lose nasal bone and septum Diagnosis 1. Ziehl-Neelsen stain |
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Term
| Clinical Presentation & diagnosis of Tuberculoid leprosy |
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Definition
Grows on low temperature areas of skin 1. Flatten plaques on the face, trunk and limbs 2. PN invasion 3. Slow progression & healing 4. Localizes to superficial nerves leading to thicken nerves 5. Non-contagious Diagnosis: Biopsy of plaques |
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Term
| What's unqiue about the cell wall of mycobacterium? |
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Definition
| Cell wall has acetylmuramic acid instead of N-glycolylmuramic acid |
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Term
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Definition
RIPES: 1. Rifampin 2. Isoniazid 3. Pyrazinadmide 4. Ethambuol 5. Streptomycin |
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Term
| Symptoms of Reactivated TB |
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Definition
Immunosuppressed 1. Persistent cough, fever, night sweats, loss of weight, tiredness 2. CXR: Cavities in the upper lobe (aerophilic) 3. Can disseminate |
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Term
| How does Primary TB present? |
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Definition
1. Can by asymptomatic or fever & maliase 2. Infiltrates in lower lobes of lung 3. Ghon complex (Calcified tubercles w/ lymph nodes) |
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Term
| Distinguish M. tuberculosis from M. leprae biochemically |
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Definition
| M. Leprae grows at low temperatures |
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Term
|
Definition
1. Pontiac fever: Flu like 2. Legionnaires disease: microabscesses seen on CXR |
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Term
Charcteristics of Chlamydia
|
|
Definition
1. Gram (-) intracellular bacteria 2. Infectious elementary body |
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Term
| What disease does C. trachomatis (A-C) cause? |
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Definition
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Term
| C. trachmatis (A-C) is the number one cause of what? |
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Definition
| Blindness via corneal scarring |
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Term
| Treatment of C. trachmatis |
|
Definition
1. Deoxycycline 2. Azithromycin |
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Term
| What does C. trachmatis (L1-L3) cause and it's description? |
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Definition
1. Lymphogranuloma Venereum 2. Painless papules that lead to swelling & tenderness of lymph nodes 3. Can lead to elephantiasis |
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Term
| How is C. trachomatis (L1-L3) contracted? |
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Definition
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Term
| What does C. trachomatis increase the risk of due to PID? |
|
Definition
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Term
| Symptoms of C. trachmatis (L1-L3) |
|
Definition
Women: 1. Vaginal discharge 2. RUQ ab. pain 3. No organism on gram stain |
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Term
| Chlamydia replicates where? |
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Definition
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Term
From were does Chlaymdia gets it's energy from? |
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Definition
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Term
| What disease does C. psittaci cause? |
|
Definition
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Term
| How does one get C. psittaci? |
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Definition
| Inhaling feces from infected birds |
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Term
| What disease can C. pneumoniae cause? |
|
Definition
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Term
| What are the symptoms of Atypical pneumonia? |
|
Definition
1. Nonproductive cough 2. Fever 3. Sore throat 4. CXR is patchy and anatomically confined |
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Term
Clincial Presentation of Treponema palldium
|
|
Definition
Primary Syphilis: Painless Chancre Secondary: Maculopapular rash on palms & soles Tiertary: Gummas "granulomas soft tissue" |
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Term
| Where does Rickettsia replicate? |
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Definition
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Term
What disease does Rickettsia rickettsii cause? What are it's symptoms
|
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Definition
Rocky Mountain spotted fever 1. Fever, headache 2. Maculopapular rash first on the plams & soles and then the trunk |
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Term
Where are you more likely to contract Rocky Mountain Spotted Fever?
|
|
Definition
| U.S. southern appalachian by ticks |
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Term
| What to you treat Rocky mountain spotted fever? |
|
Definition
Tetracycline & Chloramphenicol
think "Ricki TiCki" |
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Term
| What does R. rowazeki cause and it's symptoms |
|
Definition
Epidemic Typhus 1. Fever, headache, chills, malaise 2. Rash starting on the trunk spreading out to the palms and soles |
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Term
| How do you contract Epidemic Typhus? |
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Definition
Poor living conditions and sanitation 1. Transmitted by body louse |
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Term
| What does R. typhi cause? what are it's symptoms? |
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Definition
Endoemic Typhus 1. Fever, headache, maculopapular rash |
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Term
What disease does Coxiella burnetti cause? what are it's symptoms
|
|
Definition
Q fever
1. Fever, incubation, chills, headache
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Term
How is Q fever transmitted?
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|
Definition
Cattle 1. Shed in feces 2. Survives as a spore 3. Spore is inhaled |
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Term
What organisms are the common causes of Atypical pneumonia?
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|
Definition
Mycoplasm Legionella Chlaymdia Viruses |
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Term
| What's the common cause of pneumonia in adults? |
|
Definition
Mycoplasm C. pneumoniae S. pneumoniae |
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Term
How is Lyme disease transmitted?
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Definition
Borreila burgdorferi is transferred from mice to human via tick
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Term
Name the 3 stages of lyme disease?
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|
Definition
Stage 1 Erthema chronicum migrams: Red surrounding a clear bite mark Stage 2 Disseminated spirochetes proliferate leads to damages to CNS, heart Stage 3 Inflammatory damage to joints, brain |
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Term
| What's the treatment for lyme diesase? |
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Definition
| Doxycycline and for later stagesc ceftriaxone |
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