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A non-mitotic, or non-division, form of cell death that occurs when cells die without attempting division during the interphase portion of the cell life cycle is termed apoptosis |
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A classic method of displaying the sensitivity of a particular type of cell to radiation |
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Double-strand break in the same rung of the DNA ladder-like structure |
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Biologic damage occurring as a result of ionization of atoms on essential molecules produced by straight interaction with the incident radiation. |
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Definition
Low-LET radiation interacting with biologic tissue,causing damage to a cell primarily through an indirect action that involves the production of molecules |
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Multistage process that first involves the production of free radicals that are created by the interaction of the radiation with water (H2O) molecules. |
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Law of BergoniƩ and Tribondeau. |
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Definition
Radio-sensitivity function of the metabolic state of the cell receiving the exposure. |
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Linear energy transfer (LET) |
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Definition
The average energy deposited per unit length of track |
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Loss or change of a base in the DNA chain represents a mutation |
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Term
Oxygen enhancement ratio (OER) |
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Definition
Ratio of the radiation dose required to cause a particular biologic response of cells or organisms in an oxygen-deprived environment to the radiation dose required to cause an identical response under normal oxygenated conditions. |
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Radiation weighting factor (WR) |
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Definition
Used to calculate the equivalent dose (EqD) to determine the ability of a dose of any kind of ionizing radiation to cause biologic damage. |
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Relative biologic effectiveness (RBE) |
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Definition
Describes the relative capabilities of radiation with differing LETs to produce a particular biologic reaction. |
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Concept of radiation damage resulting from discrete and random events |
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Chemical unions created between atoms by the single sharing of one or more pairs of electrons |
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Mitotic, or genetic, death occurs when a cell dies after one or more divisions |
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The failure of the cell to start dividing on time. |
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The tissue that lines and covers body tissue |
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Conductive tissues that are found in the brain and spinal cord |
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Definition
Highly specialized tissues that contains fibers that affect movement of an organ or part of the body |
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