Term
|
Definition
osteoid osteoma osteoblastoma osteogenic sarcoma |
|
|
Term
|
Definition
ewings sarcoma myeloma lipoma (fat elements) |
|
|
Term
|
Definition
few cells- mature much stroma fwer than 5 mitoses localized |
|
|
Term
|
Definition
many cells immature much necrosis little stroma more than 10 mitoses blood metastases |
|
|
Term
|
Definition
intracomparmental - within fascial compartment |
|
|
Term
|
Definition
|
|
Term
|
Definition
low grade intracompartmental tumor |
|
|
Term
|
Definition
low grade extracompartmental |
|
|
Term
|
Definition
aggressive, penetrates bone. ANy stage with metastis. |
|
|
Term
|
Definition
|
|
Term
|
Definition
removal of tumor and surrounding tissue. used for maliganancies, usually |
|
|
Term
|
Definition
open biopsy permanant section is 96%. highest Frozen section is 80% |
|
|
Term
staging soft tissue malignancies |
|
Definition
grade, depth, size and metastasis. also bone deforming? |
|
|
Term
|
Definition
not clearly delineated
breaks through cortex |
|
|
Term
|
Definition
sharp border
intact cortex - cortex can balloon out (ABC) |
|
|
Term
|
Definition
chondroblastoma and giant cell tumor |
|
|
Term
|
Definition
chondrosarcoma, osteosarcoma and bone cysts |
|
|
Term
|
Definition
ossifying fibroma ewings sarcoma myeloma |
|
|
Term
|
Definition
LABs: CBC, ESR, CRP, alkaline phos. Imaging: XR, CT, MRI-softtissue |
|
|
Term
treatment of malignant tumors |
|
Definition
wide excision radial resection- removing entire compartment AMPUTATION |
|
|
Term
|
Definition
MC bening lesion of hand and foot |
|
|
Term
giant cell tumor of tendon sheath |
|
Definition
2nd MC lesion of hand and foot |
|
|
Term
giant cell tumor of tendon sheath |
|
Definition
golden color due to hemosiderin
Histo: multinucleated giant cells |
|
|
Term
|
Definition
bluish discoloraed mass on hand |
|
|
Term
|
Definition
soft and squishy non-tender MRI - same color as fat transforms to liposarcoma |
|
|
Term
|
Definition
epidermis gets into dermal layer and proliferates
men, 3-4 decade |
|
|
Term
|
Definition
can present as CTS! painless, volar surface, tinel sign - tap flexor retinaculum
HISTO: antoni A = palisades of tumors cells Antoni B - minimal cell. BOTH areas will be present in lesion. |
|
|
Term
|
Definition
50% have mutation of gene "schwannomin" on chrom 22 |
|
|
Term
|
Definition
tumor of fascicles of nerve |
|
|
Term
|
Definition
NF-1 - mutation of "neurofibromin" on chrom 17 NF-2 - abn chrom 22 |
|
|
Term
|
Definition
VERY painful lesion under nail ***TRIAD of sxs: intermittent severe pain cold intolerance point tenderness - VERY VERY PAINFUL |
|
|
Term
|
Definition
|
|
Term
|
Definition
MC benign bone tumor looks like popcorn on XR, usually of long bones |
|
|
Term
|
Definition
Age10-40, pathologic frxs 90% of all bone tumors in hand |
|
|
Term
|
Definition
multiple enchondromatosis, nonhereditary
30% malignant transformation to chondrosarcoma |
|
|
Term
|
Definition
soft tissue hemangiomas plus multiple enchondromas |
|
|
Term
|
Definition
has cartilage cap, can have malignant transformation |
|
|
Term
|
Definition
benign, soap-bubble appearance on XR VERY RARE - <20cases |
|
|
Term
|
Definition
benign, lytic more frequent than sclerotic
pain relieved by ASA |
|
|
Term
|
Definition
similar to osteoid osteoma but larger! >2cm |
|
|
Term
|
Definition
not really a tumor! contains fluid. in long bones FALLEN LEAF SIGN - bone fragment from pathologic frx floats in medulla. |
|
|
Term
|
Definition
common in hand -metacarpal>phalanx>carpus common in spine t(16:17) translocation Ballooning of cortex |
|
|
Term
|
Definition
aggressive, benign (lowgrade malignant) lytic epiphyseal lesion!!
hand lesion at higher risk for metastasis |
|
|
Term
|
Definition
surveillance is mand. pt must be staged: bone scan, chest XR, CT |
|
|
Term
|
Definition
distal radius lesion is more malignant - 25% metastasize to lung |
|
|
Term
|
Definition
>60 yo, prox phalanges and metacarpals! common in pelvis slow growing, firm, painful. soft tissue mass. 10%-metastasize |
|
|
Term
|
Definition
bizarre shaped chondrocyte nuclei. NOT normal= malignant |
|
|
Term
|
Definition
Must be removed surgically. does NOT respond to rad or chemo. |
|
|
Term
|
Definition
responds to chemo. lowgrade more common, usually around knee. Asso. with retinoblastoma (Rb) gene |
|
|
Term
|
Definition
rapidly enlarging, painful mass. usually around knee.
packet says in phalanges and metacarpals as well. |
|
|
Term
|
Definition
10-20 yo with pelvis lesion. t(11:22) translocation small blue round cells |
|
|
Term
|
Definition
painless mass that has been there for a long time, recent growth. |
|
|
Term
|
Definition
Risk factors: rad and herbicides |
|
|
Term
|
Definition
treat with wide excision until margins are negative. amputation Radiation: >5cm Chemo: highgrade, >10cm, lung metastases |
|
|
Term
|
Definition
near joints, mc near carpus t(x:18) translocation |
|
|
Term
|
Definition
painful with rapid growth |
|
|
Term
dermatofibrosarcoma protuberans |
|
Definition
horizontal spread, use very wide margins to excise. |
|
|
Term
Malignant fibrous histiocytoma |
|
Definition
|
|
Term
|
Definition
MC soft tissue sarcoma in children |
|
|
Term
|
Definition
|
|
Term
|
Definition
MC malignant primary bone tumor |
|
|
Term
|
Definition
lymphangiosarcoma from chornic lymphedema following mastectomy |
|
|