If 100 capsules contain 340 mg of active ingredient, what is the weight of active ingredient in 75 capsules?

1. 453 mg
2. 340 mg
3. 255 mg
4. 128 mg
5. 75 mg

3. 255 mg

x mg : 340 mg = 75 cap:100 cap

                  x = 340 mg x 75 cap/100cap

                    = 255 mg

What is the weight of 500 mL of a liquid whose specific gravity is 1.13?

A. 442 mg

B. 565 g

C. 442 g

D. 885 mg

E. 221 g

B. 565 g, because specific gravity of 1.13 corresponds to a density of 1.13 g/mL.

       density = weight/volume; thus weight

                  = density x volume = 1.13 g/mL

                    x 500 mL = 565 g

A pharmacist weighs out 325 mg of a substance on her class A prescription balance. When she subsequently checks the weight on a more sensitive analytical balance, she finds it to be only 312 mg. What is the percentage of error in the original weighing?

A. 4%

B. 5%

C. 6%

D. 10%

E. 12%

A. 4%

      % error =      (error x 100%)

                        quantity desired

                                       100

                = (325 - 312) x  325  = 4%

What is the minimum weighable quantity for a maximum 5% error using a balance with a sensitivity requirement of 6mg?

A. 80 mcg

B. 100 mg

C. 120 mg

D. 150 mg

E. 240 mg

C. 120 mg

minimum weighable quantity = SR x 100%

                                              5%

                                     = 6 mg x 100%

                                                    5%

                                     = 120 mg

A patient weighing 175 lbs is to receive an initial daily IM dosage of procainamide HCl (500 mg/mL vial) of 50 mg/kg (ABW) to be given in divided doses every 3 hours. How many milliliters should each injection contain?

A. 3.98 mL

B. 0.49 mL

C. 8.23 mL

D. 1.87 mL

E. 0.99 mL

E. 0.99 mL

daily dosage = 50 mg/kg x 175 lb

                                   2.2 lb/kg

                 = 3,997 mg

single IM injection = (3,997/8)mg x         1        

                                                  500 mg/mL

                        = 0.99 mL

What is the IBW of a female patient whose height is 5 feet 8 inches?

A. 68 kg

B. 64 kg

C. 150 lbs

D. 121 lbs

E. 53 kg

B. 64 kg

IBW = 45.5 + (2.3 x 8) = 64 kg

What is the approximate BSA of an adult patient who weighs 154 lbs and is 6 feet tall?

A. 1.73 m²

B. 3.15 m²

C. 1.89 m²

D. 0.70 m²

E. 2.67 m²

C. 1.89 m²

weight =      154 lbs     = 70kg

                   2.2 lb/kg

height = 6 ft x 12 in/ft x 2.54 cm/in = 183 cm

BSA = square root [ 70 x 183   ]

                                  3,600

      = square root [3.56] = 1.89 m²

If the adult dose of a drug is 125 mg, what is the dose for a child whose BSA is estimated to be 0.68² ?

A. 485 mcg

B. 318 mg

C. 85 mg

D. 49 mg

E. 33 mg

D. 49 mg

child dose = adult dose x child BSA = 125 mg

                     1.73

                x    0.68 m²     = 49 mg

                     1.73 m²

What is the CrCl for a 65 year old female who weighs 59 kg and has a serum creatinine level of 1.3 mg/dL?

A. 34 mL/min

B. 40 mL/min

C. 26 mL/min

D. 82 mL/min

E. 100 mL/min

A. 34 mL/min

CrCl = 0.85 x ( 140 - 65 ) x       50     

                                      (72 x 1.3)

       - 34 mL/min

Using the fomula that follows, determine how much zinc oxide is required to make 750 g of mixture:

Formula : Zinc Oxide    150 g

              Starch         250 g

             Petrolatum     550 g

              Coal Tar          50 g

A. 200 g

B. 188 g

C. 413 g

D. 113 g

E.  38 g

D. 113 g : Note that the formula will produce a total of 1,000 g of the mixture. Then, by proportions:

 x g ZnO: 150 g ZnO = 750 g mix : 1,000 g

                            = 150 g x    750 g    = 113 g

                                           1,000 g

If the pK_a of a weak acid drug is 2.5, at which pH will this drug become more ionized?

A. pH 5

B. pH 2.5

C. pH 1.5

D. pH 1