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NBCE Part 1
LaRose Endocrine
83
Health Care
Professional
08/23/2012

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Cards

Term
1.       Although the pituitary gland is called the master control gland in the endocrine system, it is under the control of the _____.
Definition
HYPOTHALAMUS
Term
2.       What is another name of the anterior pituitary?
Definition
ADENOHYPOPHYSIS
Term
3.       This hormone released by the anterior pituitary governs the synthesis of cortisol in the adrenal cortex.
Definition
ACTH
Term
4.       ACTH release is stimulated by _____.
Definition
CRH (CORTICOTROPHIN RELEASING HORMONE)
Term
5.       Increased ACTH is seen in this condition.
Definition
CUSHING’S SYNDROME
Term
6.       This hormone released by the anterior pituitary stimulates the follicles in the ovaries to produce estrogen, and the sertoli cells for spermatogenesis.
Definition
FSH
Term
7.       FSH release is stimulated by _____.
Definition
GNRH (GONADOTROPHIN RELEASING HORMONE)
Term
8.       This hormone secreted by the anterior pituitary stimulates bone and tissue growth seen through somatomedins A-C.
Definition
GROWTH HORMONE (SOMATOTROPHIN)
Term
9.       The release of GH is governed by _____.
Definition
GROWTH HORMONE RELEASING HORMONE (GHRH)
Term
10.   Increased GH release results in either _____ or _____.
Definition
GIGANTISM OR ACROMEGALY
Term
11.   Decreased GH release results in _____.
Definition
DWARFISM
Term
12.   _____ is a hormone released by the anterior pituitary that stimulates the thyroid gland to produce thyroxin.
Definition
TSH
Term
13.   The release of TSH is stimulated by _____.
Definition
THYROTROPHIN RELEASING HORMONE
Term
14.   Increased thyroxin results in _____.
Definition
HYPERTHYROIDISM (THYROTOXICOSIS)
Term
15.   Decreased thyroxin results in _____.
Definition
HYPOTHYROIDISM (MYXEDEMA)
Term
16.   This hormone released by the anterior pituitary promotes breast development and milk production.
Definition
PROLACTIN
Term
17.   The release of prolactin is affected by both _____ and _____.
Definition
PROLACTIN INHIBITING FACTOR, TRH
Term
18.   What is another name of the posterior pituitary?
Definition
NEUROHYPOPHYSIS
Term
19.   This hormone stored in the posterior pituitary is secreted by the paraventricular nucleus in the hypothalamus.
Definition
OXYTOXIN
Term
20.   Oxytoxin does these 2 things to the female body.
Definition
1) STIMULATES CONTRACTION OF THE UTERINE MUSCLE, 2) STIMULATES MILK EJECTION
Term
21.   Oxytoxin is a strong hormone that plays a role in _____.
Definition
MATERNAL BONDING
Term
22.   _____ hormone is secreted by the supraoptic nucleus of the hypothalamus.
Definition
ADH
Term
23.   ADH is released in response to _____, and acts on the _____ of the kidneys.
Definition
WATER DEPRIVATION; COLLECTING DUCTS
Term
24.   Decreased ADH leads to _____, which is characterized by polyuria and polydipsia.
Definition
DIABETES INSIPIDUS
Term
25.   _____ lies between the anterior and posterior pituitary lobes.
Definition
PARS INTERMEDIA
Term
26.   The pars intermedia secretes _____, which stimulates the production of melanin by the melanocytes in the skin.
Definition
MELANOCYTE STIMULATING HORMONE
Term
27.   Mealocyte stimulating hormone is produced from _____, from which both MSH and ACTH are formed.
Definition
PRO-OPIOMELANCORTIN
Term
28.   In the thyroid gland under the stimulation of TSH, _____ combines with _____ and binds to the thyroglobulin molecule within the follicles to form mon-iodo-tyrosine (MIT).
Definition
IODINE; TYROSINE
Term
29.   2 molecules of MIT are coupled to form _____.
Definition
DI-IODO-TYROSINE (DIT)
Term
30.   2 DIT’s combine to form _____.
Definition
T4 (TETRA-IODO-TYROSINE)
Term
31.   1 DIT coupled with 2 DIT’s form _____.
Definition
T3
Term
32.   What is the active hormone T3 or T4?
Definition
T3
Term
33.   T4 is converted to _____ in the periphery, which increases metabolism.
Definition
T3
Term
34.   What is another name of hyperthyroidism?
Definition
GRAVES DISEASE
Term
35.   Graves disease results in these 3 conditions.
Definition
1) EXOPHTHALMOS, 2) WEIGHT LOSS, 3) TREMORS
Term
36.   Hypothyroidism results in _____ in children and _____ in adults.
Definition
CRETINISM; MYXEDEMA
Term
37.   Hypothyroidism causes these 3 conditions.
Definition
1) WEIGHT GAIN, 2) COARSE HAIR, 3) DECREASED METABOLISM
Term
38.   The parafollicular cells of the thyroid gland secrete _____.
Definition
CALCITONIN
Term
39.   What is the function of calcitonin?
Definition
TAKES CALCIUM FROM THE BLOOD AND PUTS IT BACK INTO BONE
Term
40.   These 2 hormones play a role in calcium metabolism.
Definition
CALCITONIN AND PTH
Term
41.   Parathyroid hormone is secreted by the _____ cells of the parathyroid glands.
Definition
CHIEF CELLS
Term
42.   _____ takes calcium from the bone and puts it into the blood.
Definition
PARATHYROID HORMONE
Term
43.   Parathyroid hormone increases _____ in the kidney by acting on the cells in the distal convoluted tubules.
Definition
CALCIUM RESPORTION
Term
44.   _____ is caused by hypoparathyroidism.
Definition
HYPOCALCEMIA
Term
45.   Hypocalcemia due to hypoparathyroidism excites the nervous system and results in _____ and _____.
Definition
TETANY AND MUSCLE SPASM
Term
46.   _____ is due to hyperparathyroidism and results in _____.
Definition
HYPERCALCEMIA; MUSCLE FATIGUE
Term
47.   _____ is a mineralcorticoid released by the zona-glomerulosa that acts on the kidney to regulate sodium resportion in the distal convoluted tubule.
Definition
ALDOSTERONE
Term
48.   Alsoterone release causes _____ and a _____.
Definition
WATER RETENTION; INCREASE IN BLOOD PRESSURE
Term
49.   Excess aldosterone is senn in primary hyperalosteronism which is called _____.
Definition
CONN’S SYNDROME
Term
50.   Conn’s syndrome results in these 3 conditions.
Definition
1) HIGH SODIUM, 2) HYPERTENSION, 3) LOW POTASSIUM
Term
51.   _____ is the main glucocorticoid secreted by the zona-fasciculata of the adrenal gland.
Definition
CORTISOL
Term
52.   6 functions of cortisol.
Definition
1) INCREASES LIPOGENESIS, 2) INCREASES GLYCOGENESIS, 3) INCREASES GLUCONEOGENESIS, 4) MAINTAINS BP, 5) DECREASED BONE FORMATION, 6) SUPPRESSES INFLAMMATION
Term
53.   These 3 hormones are derived from anfrosteinone secreted by the zona reticularis.
Definition
1) ESTROGEN, 2) PROGESTERONE, 3) TESTOSTERONE
Term
54.   Destruction of the adrenal cortex results in _____ which affects all 3 layers of the cortex.
Definition
ADDISON’S DISEASE
Term
55.   Addison’s disease causes these 3 conditions.
Definition
1) WEIGHT LOSS, 3) LOW BP, 3) BRONZING OF THE SKIN
Term
56.   All of the adrenal cortex hormones are produced from _____.
Definition
CHOLESTEROL
Term
57.   The adrenal medulla secretes a lot of _____, but also secretes _____.
Definition
EPINEPHRINE; NOR-EPINEPHRINE
Term
58.   The adrenal medulla behaves like a _____ as it is supplied by preganglionic fibers.
Definition
SYMPATHETIC GANGLION
Term
59.   Nor-epinephrine is produced from _____, which is derived from _____.
Definition
TYROSINE; PHENYLALANINE
Term
60.   Epinephrine is produced from _____.
Definition
NOR-EPINEPHRINE
Term
61.   Epinephrine and nor-epinephrine are transmitters in the _____ nervous system.
Definition
SYMPATHETIC
Term
62.   9 functions of epinephrine and norepinephrine in the sympathetic nervous system.
Definition
1) INCREASE HEART RATE, 2) DILATE BLOOD VESSELS, 3) DILATE ARTERIES TO SKELETAL MUSCLE, 4) DILATE THE BRONCHI AND PUPIL, 5) DECREASE GUT MOTILITY, 6) CONSTRICT BLADDER AND BOWEL SPHINCTERS, 7) CONTRACT ERECTOR PILLI MUSCLES IN THE SKIN, 8) DECREASE SALIVARY SECRETION, 9) INCREASE SWEAT PRODUCTION
Term
63.   Increased secretion of nor-epinephrine is seen in this adrenal medulla tumor.
Definition
PHEOCHROMOCYTOMA
Term
64.   Pheochromocytoma results in these 4 p’s.
Definition
1) PERSPIRATION, 2) HEART PALPITATIONS, 3) PAROXYSMS OF HYPERTENSION, 4) PRESSURE HEADACHES
Term
65.   The endocrine cells in the pancreas are found in the _____.
Definition
ISLETS OF LANGERHANS
Term
66.   Insulin is secreted by _____ type of islet cells.
Definition
BETA
Term
67.   This hormone moves glucose from in the blood to inside the cells.
Definition
INSULIN
Term
68.   This transporter carries glucose to the erythrocytes and the brain.
Definition
GLUT 1
Term
69.   This transporter carries glucose to the liver and beta islet cells.
Definition
GLUT 2
Term
70.   This transporter carries glucose the neurons.
Definition
GLUT 3
Term
71.   This transporter carries skeletal muscle and adipose tissue.
Definition
GLUT 4
Term
72.   Insulin promotes the synthesis of _____, _____ and _____ as cell as cellular uptake of _____.
Definition
FAT, GLYCOGEN AND PROTEIN; POTASSIUM
Term
73.   The release of insulin inhibits these 3 processes.
Definition
1) GLUCONEOGENESIS, 2) LIPOLYSIS, 3) PROTEIN DEGRADATION
Term
74.   Insulin secretion is also stimulated by the amino acids _____ and _____.
Definition
ALANINE AND LEUCINE
Term
75.   Excess insulin is seen in insulin secreting tumors such as _____, which produces low blood sugar.
Definition
INSULINOMA
Term
76.   Decrease insulin secretion or function results in _____.
Definition
DIABETES MELLITUS
Term
77.   4 signs and symptoms of diabetes mellitus.
Definition
1) POLYURIA, 2) POLYDYPSIA, 3) POLYPHAGIA, 4) PRURITIS
Term
78.   _____ is secreted by the alpha cells of the pancreas.
Definition
GLUCAGON
Term
79.   _____ causes the liver to convert glycogen to glucose (promotes glycogenolysis).
Definition
GLUCAGON
Term
80.   This hormone is secreted when blood glucose levels are low.
Definition
GLUCAGON
Term
81.   This hormone is secreted by delta cells of the pancreas.
Definition
SOMATOSTATIN (GROWTH HORMONE)
Term
82.   Somatostatin is also secreted by D cells in the _____ and by the _____.
Definition
STOMACH; HYPOTHALAMUS
Term
83.   Growth hormone (somatostatin) inhibits these 5 things.
Definition
1) RENIN, 2) INSULIN, 3) GROWTH HORMONE, 4) GASTIN, 5) GLUCAGON
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