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Neurobiology
Neuroanatomy test
106
Other
Undergraduate 2
11/23/2016

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Term
What is the insula?
Definition
is a portion of the cerebral cortex folded deep within the lateral sulcus (the fissure separating the temporal lobe from the parietal and frontal lobes).

The insulae are believed to be involved in consciousness and play a role in diverse functions usually linked to emotion or the regulation of the body's homeostasis. These functions include perception, motor control, self-awareness, cognitive functioning, and interpersonal experience.
Term
Where is the precentral gyrus found and why is it important?
Definition
frontal lobe
gives rise to a series of motor neurones which enable muscles of the body to move
Term
Where is the postcentral gyrus found and why is it important?
Definition
parietal lobe
receives a series of sensory fibres
Term
Where does the superior cerebellar peduncle come from
Definition
midbrain
Term
Where does the middle cerebellar peduncle come from
Definition
pons
Term
Where does the inferior cerebellar peduncle come from
Definition
medulla
Term
Which ventricles communicate with each other and how?
Definition
lateral ventricles and the third ventricles by the interthalamic foramen

third with the fourth via cerebral aqueduct
Term
Where are the motor and sensory cortices?
Definition
motor = postcentral gyrus
sensory = precentral gyrus
Term
Where is wernickes area and what is it responsible for?
Definition
Wernicke's area is classically located in the posterior section of the superior temporal gyrus (STG) in the (most commonly) left cerebral hemisphere.

temporal association cortex. Damage results in speech that is fluent but makes little sense.
Term
Where is brocas area and what is it responsible for?
Definition
Broca's area is found in the frontal lobe

frontal association cortex. Lesions affect ability to produce language efficiently (Broca’s aphasia)
Term
where is the auditory cortex located
Definition
The primary auditory cortex is located in the temporal lobe
Term
where is the gustatory cortex located?
Definition
It is comprised of the anterior insula on the insular lobe and the frontal operculum on the frontal lobe.
Term
where is the somatosensory association area?
Definition
on the parietal lobe behind the primary somatosensory cortex
Term
What and where is the cingulate gyrus
Definition
arched convolution that lies next to the corpus callosum and is separated from it by the sulcus of the corpus callosum.
Term
What is the fornix?
Definition
flattened bundle of white matter fibres within the corpus callosum
Term
Where is the fornix?
Definition
between the hippocampus and the hypothalamus.
Term
Where and what is the optic chiasm?
Definition
the X-shaped structure just in front of the pituitary gland formed at the point below the brain where the two optic nerves cross over each other.
Term
Where are the mammillary bodies?
Definition
The mammillary bodies are a pair of small round bodies, located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix
Term
What are the mammillary bodies?
Definition
Mammillary bodies, and their projections to the anterior thalamus via the mammillothalamic tract, are important for recollective memory.
Term
What is the role of the pineal gland?
Definition
important endocrine gland that produces melatonin.
Melatonin secreted by the pineal gland enters the bloodstream, where it flows to its target cells throughout the body. In the brain, it causes a sense of drowsiness that is associated with nighttime.
Term
Where is the pineal gland?
Definition
attached directly to the brain along the body's midline at the union of the superior colliculi of the midbrain and the lobes of the thalamus
Term
Where is the pituitary gland and what are its functions
Definition
The pituitary gland is a pea-sized structure located at the base of the brain, just below the hypothalamus, to which it is attached via nerve fibers.

It is part of the endocrine system and produces critical hormones, which are chemical substances that control various bodily functions.
Term
Where is the hypothalamus
Definition
inferior to the thalamus and anterior to the midbrain
Term
Which cranial nerves do not come off the brain stem
Definition
olfactory and optic nerve
Term
Which structure lies most rostrally – the optic chiasm or the mammillary bodies?
Definition
optic chiasm
Term
which of the cerebellar peduncles connects the pons to the cerebellum
Definition
middle (largest)
Term
What is the fluid produced in the ventricular system
Definition
cerebrospinal fluid
Term
The “interventricular foramen” connects which structures of the ventricular system?
Definition
lateral and third ventricles
Term
What is the clinical term for a rise in intracranial pressure due to obstruction to the flow of CSF?
Definition
hydrocephalus
Term
Which points of the ventricular system would be most susceptible to blockage?
Definition
narrowest points, i.e. cerebral aqueduct, interventricular foramen
Term
Are you more likely to find large neuronal cell bodies in the ventral horn, the dorsal horn, or the lateral column?
Definition
ventral horn
Term
At which spinal segment can the lateral horn be clearly seen
Definition
thoracic
Term
Regarding the tracts arising in the red nucleus and the tectum, which lies most dorsally?
Definition
rubrospinal (vs tectospinal)
Term
Which lies more laterally, the fasciculus cuneatus or the fasciculus gracilis?
Definition
fasciculus cuneatus
Term
Which is/are the only nerve (s) to exit/enter the dorsal surface of the midbrain/brainstem?
Definition
trochlear
Term
Which nerves are necessary for controlling the extraocular muscles?
Definition
oculomotor, trochlear, abducens
Term
Which nerves have both efferent and afferent branches?
Definition
trigeminal, facial, glosopharyngeal, vagus
Term
Which nerve would be used (most) to carry information relating to very sweet food?
Definition
facial
Term
Which nerve would be used (most) to carry information relating to very bitter food?
Definition
glossopharyngeal
Term
Which nerve do you use to control chewing?
Definition
trigeminal
Term
Describe the olfactory bulb
Definition
site of preliminary processing of olfactory receptor neurone afferents
Term
Describe the optic chiasma
Definition
site of hemidecussation of optic nerve fibres
Term
Describe mammillary bodies
Definition
part of limbic system, receiving hippocampal afferents projecting to thalamus
Term
Describe the pons
Definition
connection between cerebrum and cerebellum involved in coordination of movement
Term
Describe the medulla
Definition
peripheral control centre and origination of seven cranial nerves
Term
Describe the cerebellum
Definition
fine tuning and coordination of movement and posture / balance
Term
Describe the Superior colliculus
Definition
Receives visual input and orientates movements of head and eyes
Term
Describe the periaqueductal grey
Definition
Midbrain region involved in perception and descending modulation of pain
Term
Describe the inferior olive
Definition
Medullary nucleus that sends information to cerebellum; control of movement
Term
Describe the raphe nucleus
Definition
5-HT containing neurones projecting widely
Term
Describe the red nucleus
Definition
Midbrain motor nucleus projecting to spinal cord and cerebellum
Term
Describe the substantia gelatiosa
Definition
i. Outermost layers of dorsal horn receiving Adelta and C fibre nociceptive afferents
Term
Describe the spinothalamic tract
Definition
Ascending contralateral pathway conveying mainly nociceptive and thermal sensations
Term
Describe the corticospinal tract
Definition
Descending motor pathway consisting of axons of upper motor neurones en route to spinal cord
Term
Describe the Lissauer's tract
Definition
Short-range ascending/descending spinal tract for primary afferents
Term
Describe the clinical consequences of Thoracic spinal cord hemilesion
Definition
Ipsilateral loss of propioception and upper motor neurone signs (hemiplegia/monoplegia) plus contralateral loss of pain and temperature sensation
Term
Describe the clinical consequences of Unilateral brainstem lesion
Definition
Ipsilateral cranial nerve dysfunction, contralateral spastic hemiparesis, hyperreflexia, extensor plantar response, contralateral hemisensory loss and ipsilateral incoordination
Term
Describe the clinical consequences of Unilateral cerebellar hemispheric lesion
Definition
ipsilateral incoordination of the arm / leg, impaired coordination of eye movements (nystagmus)
Term
Describe the clinical consequences of Unilateral cerebral hemispheric lesion
Definition
Mental impairment, contralateral spastic hemiparesis, hyperreflexia, extensor plantar response and contralateral hemissensory loss
Term
Describe the clinical consequences of Left optic tract lesion
Definition
Homonymous hemianopia – loss of sight in right visual fields from both eyes
Term
Describe the causes of Hemiballismus
Definition
damage (eg lesion, stroke, tumour) to nuclei of the basal ganglia, usually subthalamic nucleus
Term
Describe the causes of Subdural haemotoma
Definition
rupture of superficial cerebral veins in transit from the brain to an intracranial venous sinus
Term
Describe the causes of Hydrocephalus
Definition
accumulation of cerebrospinal fluid in the ventricular system normally caused by obstruction of CSF circulation (foramina opening the 4th ventricle to subarachnoid space)
Term
Describe the causes of Multiple sclerosis
Definition
demyelination of axons Cause unclear, but could be immune (T cell attack), environmental, genetic or due to infection
Term
Describe the cause of Upper motor neurone disease
Definition
interruption of corticospinal tract; causes: stroke; spinal cord transection
Term
Describe the cause of Trigeminal neuralgia
Definition
pain in territory of one or more major divisions of trigeminal nerve, caused by underlying osteitis of petrous temporal bone, compression of sensory nerve or unknown cause
Term
Describe the cause of Bell’s palsy
Definition
caused by neuritis (possibly viral) of facial nerve causing inflammation of nerve and resulting facial paralysis
Term
What forms the roof of the lateral ventricle?
Definition
corpus callosum
Term
What forms the floor of the lateral ventricle?
Definition
The anterior part of the body of the fornix, the choroid plexus, lateral dorsal surface of the thalamus, stria terminalis, and caudate nucleus
Term
Where is the interventricular foramen
Definition
The interventricular foramen is located between the thalamus and anterior pillar of the fornix, at the anterior margin of the body. The 2 interventricular foramens (or foramina of Monro) connect the lateral ventricles with the third ventricle.
Term
What forms the lateral walls of the third ventricle
Definition
thalamus and hypothalamus
Term
Where and what is the fourth ventricle?
Definition
The fourth ventricle is connected to the third ventricle by a narrow cerebral aqueduct. The fourth ventricle is a diamond-shaped cavity located posterior to the pons and upper medulla oblongata and anterior-inferior to the cerebellum.
Term
Describe the cerebral crus
Definition
connects to cerebrum to the pons
cortiocospinal tracts
Term
What forms the basal nuclei?
Definition
putamen
globus pallidus
caudate nucleus
Term
What is the corpus striatum?
Definition
putamen and caudate nucleus
Term
Where is the hippocampus
Definition
medial temportal lobe
posterior
two hands cupping
Term
Where is the amyglada
Definition
rostral to hippocampus
Term
where is the somatosensory association area?
Definition
superior posterior
Term
Where is the visual cortex?
Definition
bottom of occipital lobe
Term
Where is the auditory cortex?
Definition
superior temporal lobe
Term
Where is the gustatory cortex?
Definition
inferior parietal lobe, at the bottom of the somatosensory cortex
Term
What do ascending tracts deliver?
Definition
sensory information to the brain
Term
What do descending tracts deliver?
Definition
motor information to the periphery
Term
What does it mean if the tract name begins with spino-?
Definition
the tract is a sensory tract delivering information from the spinal
cord
Term
What does it mean if the tract name ends with -spinal?
Definition
the tract is a motor tract that delivers information from the X to the spinal cord
Term
Describe a first-order neuron
Definition
• Delivers sensations to the CNS
• The cell body is in the dorsal or cranial root ganglion
Term
Describe a second-order neuron
Definition
An interneuron with the cell body in the spinal cord or brain
Term
Describe a third-order neuron
Definition
Transmits information from the thalamus to the cerebral cortex
Term
What effect does the height at which a sensory neurone enters the spinal cord have?
Definition
lower level = more medial to the spinal cord (therefore higher entrance = more lateral to the spinal cord)
Term
What does the spinothalamic tract transmit?
Definition
Transmits pain and temperature sensations to the thalamus and then to the cerebrum
Term
What does the spinocerebellar tract transmit?
Definition
Transmits proprioception (position of self and movement) sensations to the cerebellum
Term
What does the corticospinal tract transmit?
Definition
Conscious control of skeletal muscles
Term
What does the subconscious tract transmit?
Definition
Subconscious regulation of balance, muscle tone, eye, hand, and upper limb position
Term
What are the 4 subconscious tracts
Definition
• Vestibulospinal tracts
• Tectospinal tracts
• Reticulospinal tracts
• Rubrospinal tracts
Term
What does the vestibulospinal tract transmit
Definition
• Send information from the inner ear to monitor position of the head
• Vestibular nuclei respond by altering muscle tone, neck muscle contraction, and limbs for posture and balance
Term
What does the tectospinal tract transmit
Definition
• Send information to the head, neck, and upper limbs in response to bright and sudden movements and loud noises
• The tectum area consists of superior and inferior colliculi
Term
What information do the colliculi recieve
Definition
• Superior colliculi: receives visual information
• Inferior colliculi: receives auditory information
Term
What information does the reticulospinal tract transmit
Definition
Send information to cause eye movements and activate respiratory muscles
Term
What information does the rubrospinal tract transmit
Definition
Send information to the flexor and extensor muscles
Term
What is the cauda equina?
Definition
The spinal cord at the lumbar & sacral nerve roots are strands that are like a horses tail. (Cauda means tail, like caudal meaning toward the bottom, and equina means horse from equine/equestrian)
Term
What is the filum terminale?
Definition
This is connective tissue that helps anchor the spinal cord to the coccyx.
Term
Describe the dura mata
Definition
the tough outer layer of the meninges
Term
Describe the arachnoid mater
Definition
called this because it has spider-web/leggy appearance.
middle
Term
Describe the pia mater
Definition
(soft mother) is a very delicate layer that attaches to the spinal cord and follows the contours of the cord or brain.
inner
Term
What is the falx cerebi?
Definition
a large, crescent-shaped fold of meningeal layer of dura mater that descends vertically in the longitudinal fissure between the cerebral hemispheres.

occipiital bone
Term
What is the tentorium cerebelli?
Definition
an extension of the dura mater that separates the cerebellum from the inferior portion of the occipital lobes.
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