Term
| The development of the neuro system |
|
Definition
|
|
Term
| By the 3rd week of development, the embryo is a ____ |
|
Definition
|
|
Term
| Name the 3 germ layers of the trilaminar disc. |
|
Definition
|
|
Term
| The innermost layer of the trilaminar disc. |
|
Definition
|
|
Term
| The outermost layer of the trilaminar disc. |
|
Definition
|
|
Term
| The middle layer of the trilaminar disc |
|
Definition
|
|
Term
| This germ layer of the trilaminar disc will eventually give rise to the lungs, liver, and gut. |
|
Definition
|
|
Term
| This germ layer of the trilaminar disc will eventually give rise to the connective tissue, muscle, vascular structures, blood cells, bone marrow, and portions of internal organs. |
|
Definition
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|
Term
| This germ layer of the trilaminar disc will eventually give rise to the epidermis, CNS, and PNS. |
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Definition
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|
Term
| This is where the ecto, endo, and meso derm are not yet separated. |
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Definition
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|
Term
| In days 16-21, a structure forms from the embryonic mesoderm known as what? |
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Definition
|
|
Term
| Around what day does the mesoderm start to differentiate |
|
Definition
|
|
Term
| Defines the longitudinal axis of the embryo (rostral and caudal) |
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Definition
|
|
Term
| Determines the orientation of the vertebral column (ventral and dorsal) |
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Definition
|
|
Term
| Persists as the nucleus pulposus of the intervertebral discs |
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Definition
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|
Term
| Stimulates the ectoderm to form the neural plate. |
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Definition
|
|
Term
| A specialization of mesodermal cells. |
|
Definition
|
|
Term
| Around what day does the notochord stimulate the ectoderm to proliferate? |
|
Definition
|
|
Term
| Cells of the ectoderm begin to elongate and thicken to form a structure known as the what? |
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Definition
|
|
Term
| Once the ectoderm begins differentiating it is called something else. |
|
Definition
Neuroectoderm
Neuroepithelium |
|
|
Term
| The edges of the neural plate begin to rise and form ridges known as what? |
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Definition
|
|
Term
| The neural folds begin forming first where? |
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Definition
|
|
Term
| Where do the neural folds end at? |
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Definition
|
|
Term
| The valley between the neural folds. |
|
Definition
|
|
Term
| Neuroectodermal cells of the neural folds ____ from the adjacent ectoderm. |
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Definition
|
|
Term
| Once the neuroectodermal cells have separated, they have 1 of 2 fates. What are they? |
|
Definition
1. They can become the neural tube
2. They can become neural crest cells |
|
|
Term
| What gives rise to the neural tube? |
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Definition
|
|
Term
| If neuroectodermal cells disperse and undergo cellular migration what kind of cells will they become? |
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Definition
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|
Term
| If neuroectodermal cells stay near the midline to fuse, what do they become? |
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Definition
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|
Term
| Occurs during 3-4 wweeks of gestation. Forming the neural tube except at the caudal end. |
|
Definition
|
|
Term
| The formation of the neural tube |
|
Definition
|
|
Term
| The opening of the neural tube at the anterior end. |
|
Definition
|
|
Term
| The opening of the neural tube at the posterior end. |
|
Definition
|
|
Term
| Neural folds begin to fuse to form the neural tube on day 20 at the level of what? |
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Definition
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|
Term
| Fusion of the neural tube progresses in what direction? |
|
Definition
|
|
Term
| When is the neural tube completed? |
|
Definition
|
|
Term
| The neural tube contains lumen called what? |
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Definition
|
|
Term
| The lumen that is open at both ends initially. |
|
Definition
|
|
Term
| When does the anterior neuropore close? |
|
Definition
|
|
Term
| When does the posterior neuropore close? |
|
Definition
|
|
Term
| When the anterior neuropore closes, what is it then called? |
|
Definition
|
|
Term
| What all does primary neurulation form? |
|
Definition
Brain
Brainstem
C1-S1 Spinal Cord |
|
|
Term
| 2 other terms for defects of primary neurulation. |
|
Definition
Neural Tube Defects
Dysraphic Defects |
|
|
Term
| Occurs due to disruption of an event prior to or during the formation of the neural tube. |
|
Definition
|
|
Term
| Where do neural tube defects usually occur? |
|
Definition
| either at the anterior or posterior neuropore |
|
|
Term
| A total failure of neurulation. The neural plate lateral edges never fuse. There is no brain or spinal cord. |
|
Definition
| Craniorachischisis Totalis |
|
|
Term
|
Definition
|
|
Term
| Gives rise to the spinal cord. |
|
Definition
|
|
Term
| Failure of the anterior neuropore to close. |
|
Definition
|
|
Term
| The initial point of fusion to the posterior neuropore is normal, but there is no fusion rostral to the brainstem. |
|
Definition
|
|
Term
| When would anencephaly insult usually occur. |
|
Definition
|
|
Term
| Brain is not formed, surrounding meninges and skull may be absent. Facial abnormalities may be present. |
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Definition
|
|
Term
| Occurs in 5/10,000 live births and is fatal. |
|
Definition
|
|
Term
| Results from partial closure of the anterior neuropore. |
|
Definition
|
|
Term
| Accompanies by cyst protrusion that may contain meninges, brain, ventricular system, CSF. |
|
Definition
|
|
Term
| Where the cyst protrusion only contains CSF and meninges. |
|
Definition
|
|
Term
| Where the cyst protrusion contains CSF, meninges, and some brain. |
|
Definition
|
|
Term
| Where th cyst protrusion contains, CSF, meninges, some brain, and the ventricular system. |
|
Definition
| Meningohydroencephalocele |
|
|
Term
| Where in the head does the Cranium Bifidum? |
|
Definition
|
|
Term
| Failure of the Posterior neuropore to close. |
|
Definition
|
|
Term
| The neural plate caudal to the neck is open with no bony or skin covering. |
|
Definition
|
|
Term
| When does the insult of myeloschisis usually occur |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Associated with failure of the posterior neuropore closure. Refers to a failure of the vertebral arches to form. |
|
Definition
|
|
Term
| Where does spina bifidum usually occur? |
|
Definition
| In the lumbosacral region |
|
|
Term
| Name the 2 variations of Spina Bifidum |
|
Definition
Spina Bifida Occulta
Spina Bifida Cystica |
|
|
Term
| The only defect here is the failure of the vertebral column arches to close. The spinous processes did not form. |
|
Definition
|
|
Term
| The skin is closed over the defect; this is the least severe type of spina bifidum |
|
Definition
|
|
Term
| Occurs in about 10% of the population. No neurological defects are present, and the site of the defect may be marked by a patch of dark hair. |
|
Definition
|
|
Term
| Spina bifida accompanied by a cystic mass that protrudes through the defect. |
|
Definition
|
|
Term
| May be detected by an ultrasound after the 10th week of gestation or by measuring alpha-fetoprotein levels in amniotic fluid. |
|
Definition
|
|
Term
| Name the 3 types of cysts you can have with Spina Bifida Cystica |
|
Definition
Meningocele
Meningomyelocele
Myeloschisis |
|
|
Term
| What is the most common variation of Spina Bifida Cystica? |
|
Definition
|
|
Term
| Usually also associated with a caudal displacement of the medulla and a portion of the cerebellum into the spinal canal which causes an obstruction of the foramen magnum and obstructs the flow of CSF. |
|
Definition
|
|
Term
| Where there is a caudal displacement of the medulla and cerebellum through the foramen magnum which pinches off the subsrachnoid space not allowing CSF to circulate. |
|
Definition
|
|
Term
| Where CSF build up due to a blockage |
|
Definition
|
|
Term
| 80% of patients with Arnold-Chiari Malformation have what? |
|
Definition
|
|
Term
| Used to drain ventricles into the peritoneal cavity |
|
Definition
|
|
Term
| The most severe type of Spina Bifida |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Results in an open neural tube that lies on the surface of the back, no cyst. |
|
Definition
|
|
Term
| Formation of the sacral and coccygeal spinal cord segments (S2-C1) |
|
Definition
|
|
Term
| Formation of the sacral and coccygeal spinal cord segments (S2-C1) |
|
Definition
|
|
Term
| By 20-42 days, a group of undifferentiated ____ cells at the caudal end of the neural tube begin to grow and differentiate into a neural cord. |
|
Definition
|
|
Term
| A mass of mesodermal cells at the caudal end of the neural tube that form the sacrococcygeal region of the neural cord. |
|
Definition
|
|
Term
| Develops a central cavity that connects with the central cavity of the higher segment (S1) |
|
Definition
|
|
Term
| What 2 cavities become continuous with each other? |
|
Definition
Caudal Eminence
Neural Tube |
|
|
Term
| Defects of secondary neurulation are distinguished by what 2 things? |
|
Definition
1. Their closed skin over the lesion
2. The caudal location |
|
|
Term
| The most common defect in secondary neurulation. |
|
Definition
|
|
Term
| Where the conus medullaris and the filum terminale are fixed to the vertebral column by a fibrous band. |
|
Definition
|
|
Term
| Causes sustained traction on the spinal cord, damaging the cord and causing a loss of sensation and motor deficits in the lower extremities. |
|
Definition
|
|
Term
| Following the closure of the anterior neuropore (Day 25) there is rapid growth of neural tissue in the cranial region. What is this called. |
|
Definition
|
|
Term
| Tissue in the cranial region of the neural tube enlarges to form 3 primary brain vesicles: |
|
Definition
1. Prosencephalon (Forebrain)
2. Mesencephalon (Midbrain)
3. Rhombencephalon (Hindbrain) |
|
|
Term
| Name the 2 flexures that develop in the neural tube. |
|
Definition
Cervical Flexure
Cephalic Flexure |
|
|
Term
| This flexure occurs at the rhombencephalon/spinal cord juncture at the anatomical region of the brainstem. |
|
Definition
|
|
Term
| This flexure occurs at the level of the mesencephalon. |
|
Definition
|
|
Term
| During the 5th week, 3 primary brain vesicles become divided into 5 secondary brain vesicles. Name them. |
|
Definition
1. Telencephalon
2. Diencephalon
3. Mesencephalon
4. Metencephalon
5. Myelencephalon |
|
|
Term
| During the 5th week, what does the prosencephalon divide into? |
|
Definition
Telencephalon
Diencephalon |
|
|
Term
| During the 5th week, what does the mesencephalon divide into? |
|
Definition
| It stays the mesencephalon |
|
|
Term
| During the 5th week, what does the rhombencephalon divide into? |
|
Definition
Metencephalon
Myelencephalon |
|
|
Term
| Gives rise to the hypothalamus, thalamus, and 3rd ventricle |
|
Definition
|
|
Term
| Gives rise to the cerebral hemispheres and lateral ventricles |
|
Definition
|
|
Term
| This flexure appears in the dorsal surface of the brainstem between the metencephalon and the myelencephalon |
|
Definition
|
|
Term
| Causes this portion of the brainstem to flatten and form the thin roof of the 4th ventricle |
|
Definition
|
|
Term
| The rhrombi lip, from the region of the pontine flexure, fuses to form the ___. |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Gives rise to the medulla |
|
Definition
|
|
Term
| What separates the lateral ventricle? |
|
Definition
|
|
Term
| When the neural tube first forms, it is composed completely of what type of epithelial cells? |
|
Definition
| Pseudo-stratified columnar epithelial cells |
|
|
Term
| As the neural tube develops, the cells begin to divide and the wall of the neural tube thickens and form how many layers? |
|
Definition
|
|
Term
| Name the 3 layers in the wall of the neural tube. |
|
Definition
Ventricular Layer
Marginal Layer
Mantle Layer |
|
|
Term
| The innermost layer of the neural tube |
|
Definition
|
|
Term
| The outermost layer of the neural tube |
|
Definition
|
|
Term
| The middle layer of the neural tube |
|
Definition
|
|
Term
| Layer of cells forming the neuroepithelial layer that lines the lumen of the ventricles |
|
Definition
|
|
Term
| The cells here proliferate and differentiate into all cells of the CNS except the microglia. |
|
Definition
|
|
Term
| The ventricular layer proliferates and differentiates all cells of the CNS except which one? |
|
Definition
|
|
Term
| The cells that remain after the proliferative phase in the ventricular layer differentiate into what? |
|
Definition
|
|
Term
| These cells ultimately line the ventricular system and the central canal. |
|
Definition
|
|
Term
| This neural tube layer is devoid of cell bodies and compsed primarily of cell processes such as axons and dendrites |
|
Definition
|
|
Term
| Gives rise to the white matter. |
|
Definition
|
|
Term
| Gives rise to the gray matter. |
|
Definition
|
|
Term
| This layer of the neural tube is occupied by cells migrating from the ventricular layer. |
|
Definition
|
|
Term
| As more cells are added, the dorsal and ventral parts of this layer increase in thickness, forming the alar and basal plates. |
|
Definition
|
|
Term
| As the cells are added to the mantle layer and increasing thickness, what does this form? |
|
Definition
|
|
Term
| What is the central canal of the telencephalon? |
|
Definition
|
|
Term
| What is the central canal of the diencephalon? |
|
Definition
|
|
Term
| What is the central canal of the mesencephalon? |
|
Definition
|
|
Term
| What is the central canal of the rhombencephalon? |
|
Definition
|
|
Term
| At first, the processes of the ___ cells extend from the lumen to the external suface of the neural tube. |
|
Definition
|
|
Term
| ___ cell division occurs in the ventricular layer. |
|
Definition
|
|
Term
| The nuclei of the daughter cells migrate ___ to the marginal layer where DNA synthesis occurs, then they ___ to the ventricular zone for another round of cell division. |
|
Definition
|
|
Term
| Generated first and migrate permanently away from the ventricular zone into the mantle layer. |
|
Definition
|
|
Term
| What do neuroblasts differentiate into? |
|
Definition
|
|
Term
| The 2nd set of cells to be produced. These cells give rise to cells that migrate into the marginal and mantle layers and differentiate. |
|
Definition
|
|
Term
| What do glioblasts differentiate into? |
|
Definition
Astrocytes
Oligodendrocytes |
|
|
Term
| Some of these cells stay in the marginal layer and some go back into the mantle layer. |
|
Definition
| Glioblasts (astocytes and oligodendrocytes) |
|
|
Term
| These cells are generated and remain in the ventricular layer to line the walls of the ventricles and the central canal. |
|
Definition
|
|
Term
| What do ependymal cells make? |
|
Definition
|
|
Term
| What is posterior to the rhombencephalon? |
|
Definition
|
|
Term
| As neurons in the spinal cord migrate to their terminal positions, the mantle layer shows dorsal and ventral thickenings called what? |
|
Definition
|
|
Term
| What separates the alar and basil plates on the lateral wall of the neural tube? |
|
Definition
|
|
Term
| The dorsal and ventral midlines form the __ plate and the ___ plate. |
|
Definition
|
|
Term
| Two plates located ventrally in the cord and give rise to the ventral horns of the spinal cord. |
|
Definition
|
|
Term
| Some neuroblasts in the basal plate develop into what? |
|
Definition
| Motor neurons in the ventral horn |
|
|
Term
| What do the motor neurons innervate? |
|
Definition
|
|
Term
| Other neuroblasts from the basil plate (not motor neurons) develop into what? |
|
Definition
| Preganglionic sympathetic (T1-L2) and Parasympathetic (S2-4) neurons in the lateral horn and intermediate zone |
|
|
Term
| What do the preganglionic and parasympathetic neurons innervate? |
|
Definition
|
|
Term
| Is the motor cranial nerve medial or lateral? |
|
Definition
|
|
Term
| Is the sensory cranial nerve medial or lateral? |
|
Definition
|
|
Term
| Two plates located dorsally in the cord. |
|
Definition
|
|
Term
| Neuroblasts in the alar plate develop into what? |
|
Definition
|
|
Term
| Sensory neurons innervate the what? |
|
Definition
| Skin, joint capsules, tendon, muscle, etc |
|
|
Term
| Where are the peripheral processes of the sensory neurons located? |
|
Definition
|
|
Term
| Where are the sensory neurons that innervate visceral receptors located? |
|
Definition
|
|
Term
| The mantle layer that lies at the interface of the alar and basal plates gives rise to what? |
|
Definition
Intermediate Zone
Lateral Horns |
|
|
Term
| Spinal innervation is segmented due to segmentation of mesoderm into what? |
|
Definition
|
|
Term
| Each somite divides into: (3) |
|
Definition
Sclerotome
Dermatome
Myotome |
|
|
Term
| Form hard tissues, cartilage, and bone: vertebrae |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Give rise to motor cranial nerve nuclei |
|
Definition
|
|
Term
| Give rise to sensory cranial nerve nuclei |
|
Definition
|
|
Term
| Derivatives of dermatomes and myotomes are innervated by axons of dorsal and ventral roots of corresponding what? |
|
Definition
|
|
Term
| Gives rise to the medulla oblongata |
|
Definition
|
|
Term
| At the level of the 4th ventricle, the alar plates are forced laterally so that in the brain stem, basal plates are ___ and alar plates are ___. |
|
Definition
|
|
Term
| In the brain stem what orientation is the basal plates? |
|
Definition
|
|
Term
| In the brain stem what orientation is the alar plates? |
|
Definition
|
|
Term
| In the spinal cord what orientation is the basal plates? |
|
Definition
|
|
Term
| In the spinal cord what orientation is the alar plates? |
|
Definition
|
|
Term
| Persists in the floor of the 4th ventricle to separate the alar plates laterally and the basal plates medially. |
|
Definition
|
|
Term
| Gives rise to the pons and cerebellum |
|
Definition
|
|
Term
| The marginal layer of the basal plate region enlarges dramatically to form what? |
|
Definition
|
|
Term
| Gives rise to the midbrain |
|
Definition
|
|
Term
| The marginal layer of the mesencephalon enlarges to form what? |
|
Definition
|
|
Term
| A large bundle of nerve fibers connecting the cerebral cortex to the brain stem and spinal cord. |
|
Definition
|
|
Term
| The alar plate in the mesencephalon enlarges to become relay centers for what? |
|
Definition
| Auditory and Visual Reflexes |
|
|
Term
| Name 6 things that the Diencephalon gives rise to. |
|
Definition
1. Thalamus
2. Hypothalamus
3. Subthalamus
4. Epithalamus
5. Optic Nerve
6. Retina |
|
|
Term
| What do the alar plates form in the region of the diencephalon |
|
Definition
|
|
Term
| At the end of the 5th week, the telecephalon gives rise to two lateral expansions called what? |
|
Definition
|
|
Term
| From the telencephalic vesicles, 6 things are developed. |
|
Definition
1. Cerebral Cortex
2. Subcortical White Matter (internal capsule, corona radiata)
3. Olfactory bulb and tract
4. Basal Ganglia
5. Amygdala
6. Hippocampus |
|
|
Term
| In the cortex, neuroblasts migrate outward to a ___ position and differentiate. |
|
Definition
|
|
Term
| Subsequent waves of neuroblasts migrate through the differentiated cells to a ___ position and differentiate. |
|
Definition
|
|
Term
| The oldest cells in the cortex are the ___. |
|
Definition
|
|
Term
| In the cortex, the gray matter is situated superficial to what? |
|
Definition
|
|
Term
| The orientation of gray and white matter is flipped in the cortex than in the spinal cord. TRUE/FALSE? |
|
Definition
|
|
Term
| When are neural crest cells formed? |
|
Definition
| At the time the neural folds are formed |
|
|
Term
| Highly migratory cells that give rise to many many structures throughout the embryo |
|
Definition
|
|
Term
| All of the neurons in the PNS originate from what? |
|
Definition
|
|
Term
| Neural Crest cells give rise to all of the neurons of the PNS. The notes list 4. |
|
Definition
1. Dorsal Root Ganglia
2. Sympathetic Chain (Chain Ganglia)
3. Other Sympathetic and Parasympathetic Ganglia (Prevertebral and Superior Mesenteric Ganglia)
4. Sensory Ganglia and some cranial nerves |
|
|
Term
| Myelinating cells that arise from Neural Crest Cells. |
|
Definition
|
|
Term
| Pigmented cells of the epidermis that arise from Neural Crest Cells. |
|
Definition
|
|
Term
| If you have someone who has a depigmentation of their skin and then they have some sensory loss (weird combo). This may be a congenial problem of what? |
|
Definition
|
|
Term
| The final stage of neuroembyrology |
|
Definition
| Proliferation and Development |
|
|
Term
| As cells undergo last division, they migrate away from the ventricular zone toward the final position on guides known as? |
|
Definition
|
|
Term
| Guides to help migrate cells to where they are supposed to go. |
|
Definition
|
|
Term
| As cells migrate, they form a moving front of cell bodies between ventricular and marginal zones. What is this known as? |
|
Definition
|
|
Term
| Once cells have reached their final position within the CNS, what to they begin to do? |
|
Definition
|
|
Term
| A single axon is produced which possess one or more distal elaborations known as what? |
|
Definition
|
|
Term
| A spade-shaped extension of a growing axon that is capable of driving through tissue to reach distant targets. |
|
Definition
|
|
Term
| What guides the axon toward its target? |
|
Definition
|
|
Term
| As an axon grows, it can send out branches that will each have their own what? |
|
Definition
|
|
Term
| Some branches of the axon may terminate in areas that will ultimately not be innervated by what? |
|
Definition
|
|
Term
| Once axon's growth cone arrives at its site of termination, it undergoes biochemical and morphological changes to become what? |
|
Definition
|
|
Term
| The area that the target neuron contacted by the presynaptic process begins expressing what? |
|
Definition
| Characteristic Postsynaptic Machinery (NT receptors) |
|
|
Term
| Many synapses are formed during development, but only a subset of those formed will remain to ___ |
|
Definition
|
|
Term
| Is there competition for synapic space on neurons? |
|
Definition
|
|
Term
| A synapse that forms will persist only if it exchanges the right cues with what? |
|
Definition
|
|
Term
| The connection of cells for communication purposes. |
|
Definition
|
|
Term
| Regulated cell death to get rid of the excess of neurons. |
|
Definition
|
|
Term
| During the process of producing neurons from neuroblasts, the embryo produces ____ times more neurons than are present in the mature brain. |
|
Definition
|
|
Term
| Almost all neurons are produced by ___ weeks of gestation. |
|
Definition
|
|
Term
| After 24 weeks, a process of programmed cell death occurs known as what? |
|
Definition
|
|
Term
| Apoptosis is an active process requiring what? |
|
Definition
|
|
Term
| Some growth factors can interrupt the normal process of what? |
|
Definition
|
|
Term
| Name 2 growth factors that can limit programmed cell death. |
|
Definition
Nerve Growth Factor
Fibroblast Growth Factor |
|
|
Term
| A disease where too many neurons are being killed off. |
|
Definition
| ALS - Amyotrophic Lateral Sclerosis |
|
|
Term
| Which is more vulnerable to injury, a developing brain or a mature brain? |
|
Definition
|
|
Term
| TRUE/FALSE: Infants suffering cortical injury in prenatal or early postnatal period may show surprising functional recovery with few to no obvious deficits. |
|
Definition
|
|
Term
| In infants, apoptosis can be altered and axonal connections can be maintained that otherwise would ___ |
|
Definition
|
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Term
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Definition
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Term
| A condition where there is an abnormally large, heavy, and usually malfunctioning brain. |
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Definition
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Term
| This occurs because too many neurons survive the pruning process. |
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Definition
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Term
| Usually occurs 2 to 4 months of gestation and is influence by genetics, irradiation, alcoholism, and intrauterine infection. |
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Definition
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Term
| Symptoms of this include delayed development, convulsive disorders, corticospinal dysfunction, and seizures. |
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Definition
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Term
| What is does the prognosis for macrencephaly depend on? |
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Definition
| The underlying cause and the associated neurological disorders. |
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Term
| Where the brain is greater than average for the age and gender of the infant or child. |
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Definition
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Term
| A neurological disorder in which the circumference of the head is smaller than average for the age and gender of the infant or child. |
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Definition
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Term
| We know that microcephaly may be congenital, but can it develop in the first few years of life as well? |
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Definition
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Term
| Where the head fails to grow while the face continues to develop at a normal rate, producing a child with a small head, a large face, a receding forehead, and a loose wrinkled scalp. |
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Definition
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Term
| Are development of motor functions and speech delayed in a child with microcephaly? |
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Definition
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Term
| Hyperactivity and mental retardation are common occurrences in children with microcephaly, what does the depend on? |
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Definition
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Term
| A disorder of migration that refers to a "smooth brain" with few or no gyri or sulci. |
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Definition
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Term
| Refers to a brain that has regions with too many gyri and sulci. |
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Definition
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Term
| The least severe migration defect |
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Definition
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Term
| Refers to normal islands of tissue deposited in the wrong place. These can be focal points of epilepsy and seizures. |
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Definition
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Term
| Disorder where neuronal call bodies did not migrate outward and got stuck. |
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Definition
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Term
| The the lobes developed in a patient with Lissencephaly? |
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Definition
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Term
| Will a person will Lissencephaly have cognitive, mental, and sensory deficits? |
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Definition
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Term
| Where the brain did not divide into 2 hemispheres. There essentially is only 1 hemisphere and the lateral ventricles are connected. |
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Definition
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Term
| Holoprosencephaly defect would occur when in gestation? |
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Definition
| During the 5th week when the telencephalon was being divided and pouched out to make the 2 hemispheres |
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Term
| Can a person live if they have Holoprosencephaly? |
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Definition
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Term
| This disorder effects facial features. Child may have one eye, a central nasal cavity, and a very small mouth. |
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Definition
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