Term
What is the main give away of a Essential Tremor? x3
What is the Best initial treatment? |
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Definition
1. both rest and intention 2. BETTER with alcohol 3. Worse with Caffeine |
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Term
What is the treatment for mild disease of Parkinsonism? x3 |
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Definition
AntiCholinergic medications- --Benztropine and Trihexyphenidyl
Amantadine |
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Term
What is the treatment of Parinsonism for Severe disease? x5 |
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Definition
Dopamine agonists: pramipexole and ropinirole (Pest inital therapy for severe parkensonism)
Levodopa/carbidopa
COMT inhibitors tolcapone, entacapone
MAOi- rasagiline, selegiline
Deep brain stimulation |
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Term
what are DA antagonists used in Parkensinism?
What drug class slows progression? |
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Definition
Pramipexole and ropinirole
MAOi |
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Term
What are the COMT inhibitors? x2
what do they do? |
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Definition
tolcapone, entacapone
extend duration of levo/carddopa by blocking metabolism of DA. |
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Term
What are the MAO inhibitors used in parkensonism?
When are they used? |
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Definition
Rasagiline, selegiline
used as a single agen or an adjunct to levodopa/carpidopa |
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Term
What is the treatment for spacicity? x3
what are the tree ass symptoms of Huntingtons |
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Definition
Baclofen, dantrolene tizanadine-Alpha agonists
Movment, Memory, mood |
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Term
What is the treatment for RLS?
what is the impulsive swearing of tourette's called |
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Definition
DA agonist like: pramipexole
coprolalia |
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Term
What is the treatment for the --- in Huntingtons
Dyskinesia
Psychosis |
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Definition
Tetrabenazine
Haloperidol, quetiapine |
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Term
what is the most common SS and presentation of Multiple sclerosis
What is the cause of Ms? |
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Definition
MC is focal sensory symptomos with gait and balance,
blurry vision or visual disturbance
Ideopathic |
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Term
What is the BITest and MATest&R for MS?
What is found in lumbar puncture? |
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Definition
MRI is BIT and MAT
shows MSplaques appear white in white matter
LP show oligoclonal bands in 85% |
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Term
What is the Treatment for MS?
Acute?
to prevent Relaps?(first choice) |
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Definition
Acute: steroids
Pr: first choice is 1. Glatiramer (copolymer-1) 2. Beta- interferon
others including Natalizumab |
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Term
what MS medication can cause white matter hypo dense lesions with progressive neuro defects?
what is the diagnostic test for ALS |
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Definition
Natalizumab causes Progressive multifocal leukoencephilopathy
Electromyography |
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Term
What is the treatment for ALS? x3
name what the drugs do. |
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Definition
Riluzole-lowers glutamate Baclofen- lowers spacicity
CPAP/BiPaP, ventilation, tracheostomy |
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Term
What are the ass S&S for Charcot-Marie-Tooth?
MATest?
what is the treatment |
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Definition
Clawed foot Children
electromyography
no tx |
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Term
How can you distinguish between Bells and a seizure?
What is the treatment |
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Definition
Cant wrinkle forehead- bells Can wrinkle forehead- seizure
Prednisone |
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Term
What is the associated bug in Guillain Barre syndrome?
What is the most specific dx test?
What is the treatment |
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Definition
Campy. Jejuni
Nerveconduction/ electromyography
IVIG or plasmapheresis
not both at the same time |
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Term
What is the BITest for Myasthenia Gravis?
MATest
what Image studies should be done? |
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Definition
Acetylcholine receptor antibodies if not present anti MUSK antibodies
electromyography
get CT/MRI/CXR for thymoma |
|
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Term
What is the best initial treatment for Myasthenia gravis
then what?
if acute crisis |
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Definition
Neostigmine, pyridostigmine
Thymectomy if under 60 Prednisone if over 60
IVIG or plasmapheresis |
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