Term
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Definition
| Intermediate strength, short acting. Topical, epidural, laryngeal |
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Term
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Definition
| High potency, medium duration local anesthetic. Parenteral only. |
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Term
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Definition
| Same as lidocaine but perenteral only |
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Term
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Definition
| Low strength local anelgisic, vasoconstrictive, for nasal, laryngeal surgery |
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Term
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Definition
| Non-opioid analgesic. Good for neuralgia, inhibits NE and 5-HT reuptake |
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Term
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Definition
| General anesthetic. Facilitates GABA, anti-emetic, decrease ICP, less confusion than thiopental |
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Term
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Definition
| General anesthetic. Facilitates GABA, less respiratory depression, slower onset. Used for colonscopy, cardiac catheterization |
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Term
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Definition
| General anesthetic. Blocks NMDA receptors. Increases BP, ICP and HR. For trauma victims w/ volume depletion |
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Term
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Definition
| Fast acting general anesthetic. Good for inducing anesthesia. Drug redistribution determines length of effect. |
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Term
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Definition
| Very high MAC, coadminister with O2. |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Anelgisia, miosis, respiratory depression, sedition, anti-tussis. Works on dorsal horn or PAG.
Causes constipation, N/V, hypotension, urinary retention, pruritis |
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Term
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Definition
| 1/10 analgesic potency of morphine. Less sedation, less constipation, less addictive. Anti-tussive. CYP2D6 converts to MS in liver. |
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Term
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Definition
| 1/10 analgesic potency of MS. Short duration, addictive. |
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Term
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Definition
| Stronger than MS, long easy withdrawal. Used for detoxification, esp. for Heroin |
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Term
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Definition
| Opioid. Give w/ acetaminophen (Percocet) or w/ ASA (Percodan) or controlled release (Oxycontin) |
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Term
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Definition
| Opioid, 100x stronger than MS. Transdermal, causes some rigidity. |
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Term
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Definition
| Parenteral only, opioid. Mu antagonist, Kappa agonist - causes psychotomimesis (hallucinations) |
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Term
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Definition
| Partial agonist at Mu, can prevent withdrawal symptoms in physically dependent patients on MS or heroin. |
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Term
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Definition
| Competetive antagonist at Mu, Kappa, Delta. Blocks opioid effects, for emergency use in overdoses. |
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Term
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Definition
| Like naloxone (opioid antagonist) but PO, lasts longer. Prevents relapse in chronic alcoholics or opioid users |
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Term
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Definition
| Mimics Myelin Basic Protein (target for destruction in Multiple Sclerosis), deflects T-cell attention from neurons. |
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Term
|
Definition
| Mononcolonal Ab, blocks T-cell migration into CNS |
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Term
|
Definition
| Reduces Sx of Multiple Sclerosis |
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Term
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Definition
Anticonvulsant. Blocks Na+ channels. Hepatic metabolism, 90% albumin bound. Causes: hirsutism, gingival hyperplasia, teratogenic.
Use for: major motion seizures, chronic pain, partial seizures |
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Term
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Definition
| Anti-convulsant. Blocks Na+ channels and NE reuptake. Hepatic metabolism, induces CYP450s. Can cause agranuloctosis and rare stephens-johnson. Uses: tonic-clonic seizure, bipolar disorder, trigeminal neuralgia |
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Term
|
Definition
| Anti-convulsant, for chronic pain syndromes and bipolar too. |
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Term
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Definition
| Anti-convulsant, migraine prophylaxis. Inhibits T-type Ca+ channels, increases GABA. Causes hair loss, weight gain, risk of hepatitis. Uses: bipolar, absence, partial or generalized, chronic pain (wide uses) |
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Term
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Definition
| Anti-convulsant, inhibits thalamic T-type Ca2+ channels. For ABSENCE seizures. |
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Term
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Definition
| Anti-convulsant, inhibits T-type Ca+ channels. Renal excretion. Causes anorexia, somnolence, renal calculi. Uses: refractory partial seizure |
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Term
|
Definition
| Anti-convulsant. GABA analogue. Excreted unchanged in urine. Causes weight gain. Uses for chronic pain and partial seizures. |
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Term
|
Definition
| Anti-convulsant. GABA analog. Causes abnormal thoughts, weight gain. Use for fibromyalgia, diabetic/herpetic neuropathic pain, partial seizures |
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Term
Topiramate
[image]
[image] |
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Definition
| Anti-convulsant, migraine prophylaxis. Potentiates GABA, decrease Glu. Renal excretion. May cause kidney stones metabolic acidosis. For migraines, bipolar, chronic pain, multiple seizure types |
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Term
|
Definition
| Anti-convulsant. Mostly excreted by kidneys. No known drug interactions. For refractory seizures in adults. |
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Term
|
Definition
| Anti-epileptic. Choice for pregnant women. Causes sedition/amnesia. |
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Term
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Definition
| IV drug for status epilepticus |
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Term
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Definition
| LDOPA crosses BBB, converted to DA by DDC. |
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Term
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Definition
| Blocks peripheral DDC to reduce side effects of LDOPA. |
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Term
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Definition
| MAO-B inhibitor. Increases endogenous DA |
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Term
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Definition
| MAO-B inhibitor, increases endogenous DA |
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Term
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Definition
| mACh blocker, small benefit for Parkinsons |
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Term
|
Definition
| Antiviral, stimulates DA release in brain |
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Term
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Definition
| DA receptor agonist, longer duration than LDOPA, reduces risk of long term motor problems |
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Term
|
Definition
| DA receptor agonist, longer duration than LDOPA, better long term outcome |
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Term
|
Definition
| COMT inhibitor, given w/ LDOPA |
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Term
|
Definition
| DA receptor agonist (for advanced Parkinsons) |
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Term
|
Definition
| Ergot derived DA receptor agonist, also suppresses prolactin release |
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Term
|
Definition
| Anti-platelet (ADP receptor inhibitor), reduces risk of MI or stroke w/ less bleeding than ASA |
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Term
|
Definition
| Prophylactic for TIA or stroke. Inhibits thromboxane |
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Term
|
Definition
| Treats alzheimers by increasing cortical acetylcholine |
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Term
|
Definition
| Palliative Tx for alzheimers. Acetylcholinesterase inhibitor |
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Term
|
Definition
| For Alzheimers. NMDA receptor inhibitor (stops leaky NMDA channels) |
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Term
|
Definition
| Cholinergic agent for Alzheimers. Transdermal patch available. |
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Term
|
Definition
| Migrain abortant. 5-HT agonist, causes cerebral vasoconstriction |
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Term
|
Definition
| Migraine abortant. 5-HT agonist. Serious side effects, including fetal harm. |
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Term
|
Definition
| Beta-blocker. Good migraine prophylaxis in children. |
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Term
|
Definition
| Anti-convulsant, and prevents migraines. GABA agonist, blocks T-tuble Ca2+ channel. |
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Term
|
Definition
| Migraine prophylaxis. Inhibits 5-HT and NE reuptake |
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Term
|
Definition
| Anti-convulsant and migraine prophylaxis. Blocks Na+ channels. |
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Term
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Definition
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Term
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Definition
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Definition
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