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*gathers info about environment from PNS - depends on PNS for input *responsible for cognition, learning, memory, plans and executes voluntary movement **brain and spinal cord (encased in bone) |
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Peripheral Nervous System |
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*interface between CNS and environment **spinal and cranial nerves - segmental orientation -afferent (sensory) and efferent (motor) neurons and tracts -pairs of nerves- sensory input, motor output |
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*convey information to cell body (soma) *receive input from other neurons -increase surface area of neuron allowing communication with other neurons |
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*conveys output of cell to next neuron or muscle (motor neuron) |
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*control center (same as in other cells) |
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*contains mitochondria and membrane bound vesicles filled with neurocrine molecules -neurotransmitters released from excitation |
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*cell body, axon, dendrite |
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*2 extensions off cell body *transmission of special senses |
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*axon split into 2 branches - one to periphery and one to spinal cord *PNS sensory neuron (think dorsal root ganglion) |
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*one long axon with many dendrites *motor neurons, pyramidal cells, purkinje cells |
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*carry info about temperature, pressure, light, and other stimuli from sensory receptors to CNS |
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*carries motor info from CNS to peripheral tissues (muscles) |
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*neurons that lie entirely w/in CNS *communicate with other neurons |
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*PNS *form myelin - ensheaths unmylenated axons (only does one) *trophic support *support of growth and repair - forms channels of regrowth |
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*CNS *forms myelin - many axons can be mylenated by one (equivalent of schwann cell in PNS) |
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*CNS *mechanical and metabolic support *response to injury - glial scars |
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*CNS *phagocytosis - help remove cellular products of damage *very moblie |
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*collections cell bodies (little myelin) *CNS - cortex of cerebrum and cerebellum (mantle or covering layers of cells), nuclei (collection of CNS cell bodies) *PNS - ganglia (collection of PNS cell bodies - dorsal root ganglia - except basal ganglia in brain) |
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*collections of axons (myelin turns white) *CNS: fasciculus, funiculus, peduncle, lemniscus, commissure, tract *PNS: nerve roots and rami |
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*2 cerebral hemispheres, 1 lateral centricle in each *cerebral cortex w/ gyri and sulci *interconnection of hemispheres wia corpus callosum *several large masses of subcortical nuclei (basal ganglia: caudate nucleus, putamen, globus pallidus) *divided into lobes based on anatomy and function |
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*between brain stem and cerebrum *thalamus, hypothalamus, third ventricle, pituitary and pineal gland *together with telencephalon referred to as forebrain |
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*midbrain *cerebral aqueduct - canal connecting thrid and fourth ventricles *tectum *cerebral peduncles |
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*pons and cerebellum *cerebellum= "little brain" 2 cerebellar hemispheres and vermis (connects them) *cerebellar cortex with folia and fissures *fourth ventricle between cerebellum and pons |
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*medulla oblongata *together with mesencephalon and pons = brainstem |
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*coordinates information from other association areas, controls some behaviors *skeletal muscle movements (primary motor cortex, premotor cortex) *prefrontal association area *higher thought processes (decision making) |
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*sensory info from skin, musculoskeletal system, viscera, and taste buds *primary somatosensory cortex *sensory association area |
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*vision *visual association area *visual cortex |
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*hearing* *auditory cortex, auditory association area |
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*buried underneath fromtal and temporal lobes *taste - gustatory cortex *smell - olfactory cortex |
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*acts as the link between higher cognitive function (reasoning, primitive emotions such as fear) *surrounds brainstem - parts of several lobes |
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*sensory receptors activated by a specific stimulus (adequate stimulus) *adequate stimulus => membrane conductance change => generator potential => action potentials |
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*what the sensation is* *indicated by which sensory neurons are activated and by where the pathways of the activated neurons terminate in the brain *submodality = quality of stimuli (touch - warm vs cold) *info carried by "labeled-line code" - brain associates a signal coming from a specific group of receptors with a specific modality (stimulation of a cold receptor perceived as cold) *no matter how nerve is stimulated, modality is always the same |
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*how much sensation is present* *frequency code - includes the total number of action potentials generated per unit time in affected sensory neurons and the total number of neurons activated |
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*Where the sensation originates* *concept of receptive field = region of skin from which stimuli can evoke a response* *precise location info is usually coded by the "population code" |
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*region of skin from which stimuli can evoke a response *size varies with location *overlap - convergence of primary sensory neurons on a single secondary neuron - 2 stimuli perceived as one *small RF's increase discrimination - few neurons converge - 2 stimuli perceived as 2 |
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*when the stimulus starts and stops* *adaptation - how long neuron continues to stimulate AP's when it is constantly stimulated itself *helps define what kind of stimulus information the receptors can best encode *"temporal pattern coding" accomplishes coding of stimulus onset, duration, and offset |
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Rapidly Adapting Receptors |
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*respond to dynamic aspects of the stimulus *fire when first receive stimulus, cease if strength of stimulus constant - little response to intensity (phasic receptors) -APs fire when stimulus turned on and off |
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Slowly Adapting Receptors |
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*respond to static and dynamic aspects of stimulus *fire rapidly when first activated, then slow and maintain firing as long as stimulus is present - respond to duration of stimulus -increased generating potentials increases intensity and increases APs *tonic receptors |
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Exteroceptive somatosensory receptors |
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*provide info about skin contact with external objects - sense outside body coming in |
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Proprioceptive somatosensory receptors |
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*provide info about body/limb postition and movement - relies primarily on receptors in joins, muscles, tendons |
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Enteroceptive somatosensory receptors |
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*monitor internal state of body and includes mechanoreceptors that detect distention of the gut or fullness of bladder |
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*sense pressure, vibration, gravity, acceleration, sound, touch -respond to mechanical energy |
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*respond to pain, some itch |
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Rapidly adapting receptors |
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*signal dynamic (active or changing) stimulus properties -e.g. movement of skin, velocity, acceleration |
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Slowly adapting receptors |
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*signal static (steady state) properties -e.g. stimulus duration, intensity |
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*senses vibration*-deep skin layers *rapidly adapting *large receptive field (vibration travels easily through body) *responding at acceleration points in skin indentation (vibration detector) *encapsulated ending-mechanical filter detecting movement *A-beta fiber (large, myelinated, fast conducting) |
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*responds to flutter and stroking (slow vibrations) *rapidly adapting *small receptive field *A-beta fibers *responts to velocity changes (skin movement)with not response to steady indentation, doesnt respond as much when stimulus removed *capsule is flattened epithelial cells - superficial skin layers |
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*responds to skin stretch* *slowly adapting *large receptive field - stretch sensitive *A-beta fibers *responds to dynamic and static phase of skin indentation - shut down when pulled off skin *pressure receptor - frequency increases with intensity *deep layer of skin |
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