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Definition
Blocks ACh muscarinic receptors.
Clinical:
1)relaxes muscles in the eye causing pupil to dilate. Used when the eye is inflammed during and eye exam.
2) Slows the activity of stomach and intestinal track and reduces acid secretion
3) Has been used some for Parkinson's |
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Definition
Blocks ACh CNS muscarinic receptors
Clinical: Used to prevent motion sickness |
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Definition
| Blocks ACh muscarinic receptors |
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Definition
Mimics ACh
Clinical: Treats urinary retention and stimulates movement of intestines |
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Definition
Blocks ACh breakdown by inhibiting AChEsterase
Clinical: Used to diagnose and treat myasthesia gravis |
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Definition
| Inhibits ACh release from presynaptic neuron |
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Definition
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Definition
Blocks ion flow through the GABA A receptor.
This inhibits Chlorine traveling through the receptor which leads to seizures |
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Definition
| Bind to the Beta subunit of GABA A and increase the ability of the endogenous transmitter to do its job |
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Definition
| (aka Valium) Binds to the Gamma subunit of GABA A receptor and enhances the ability of the endogenous transmitter to do its job (pump CL GABA pump!) |
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Definition
| Blocks binding of glycine to its receptor (Found as a Rat poison!) |
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Definition
| Blocks the action of acetylcholine esterase. This increases the duration of the end plate potential |
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Definition
| Competitive inhibitor of acetyl choline. It doesn't block K or Na conductance |
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Definition
Inhibits Na/K pump
We can still generate an AP in the presence of Oubain. Over a long period of time sodium accumulates inside the cell which eventually leads to problems |
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Definition
| Blocks the voltage dependent Na channels |
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Definition
| Abolishes voltage dependent changes in K permability |
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Definition
| Inhibits the uptake of Monoamine neurotransmitters into storage vesicles |
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Definition
| Dopamine, Norepinephrine, and Epinephrome |
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Definition
| Acts by blocking the transport of Monoamine neurotransmitters back into the presynaptic terminal |
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Term
| What is Dopamines metabolite? |
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Definition
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| Name the metabolite for Norepinephrine |
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Definition
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Term
| Name the metabolite for Serotonin |
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Definition
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Definition
| Neuropeptides that have effects that depress the effects of a second transmitter |
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Term
| Name the disease that is caused by the degeneration (partially) of cholinergic neurons of the CNS. |
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Definition
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Term
| What disease is caused by uncontrolled recuitment of electrical activity in nerve cells? |
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Definition
| Epilepsy (Picrotoxin can cause seizures by blocking GABA A) |
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Definition
| A neurodegenerative disease associated with abnormal involuntary movements due to the repeated mutation in the huntingtin gene |
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Term
| What diesease is associated with sensory and motor neuron losses due to demyelination? |
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Definition
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Definition
| Delusions and hallucinations believed to be due to imbalances in the dopamine and glutamate nuerotransmitter systems |
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Term
| What disorder is due to degeneration of dopamine neurons in the substantia nigra-basal ganglia pathway? |
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Definition
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Definition
| A Calcium independent homophilic neuronal adhesion molecule. Each N-CAM binds to another N-CAM |
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Definition
| Clusterine of pre-existing ACh receptors and other components of the neuromuscular junction |
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Definition
Irreversible inhibitor of MAO, thereby blocking monoamine degradation.
DA---> DHPA (via MAO)
NE-->DHPGA (via MAO)
5-HT---> 5-HIAA (via MAO)
MAO stands for Monoamine oxidase |
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