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NSAIDs
NSAIDs
8
Pharmacology
Graduate
03/31/2011
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Term
Aspirin (ASA)
 Definition
Irreversibly acetylates COX-1/2
Fully blocks COX-1
Partially blocks COX-2 (Anti-inflammatory 15-Epilipoxin formed)
Term
Mesalamine
 Definition
5-AminoSA
Treat IBS
Useful Topically
Term
Olsalazine
 Definition
5-AminoSA
Treat IBS
Term
Sulfasalazine
 Definition
5-AminoSA
Treat IBS
Term
Celecoxib (Celebrex)
 Definition
Selective COX-2 Inhibitor
Treat arthritis pain/inflammation
Term
Acetaminophen (Tylenol)
 Definition
NOT Anti-inflammatory
No adverse side effects
Term
Ibuprofen (Motrin/Advil)
 Definition
Propionic Acid Derivative
Term
Neproxen (Aleve)
 Definition
Propionic Acid Derivative
Longer half-life than Ibuprofen
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