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Nucleic Acids
DNA & RNA
16
Biology
Undergraduate 1
10/11/2008

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Term
Nucleotides
Definition

are the subunits of nucleic acids, each nuceotide has 3 parts:

 

- ribose (a sugar)

- 3 phosphates (attached to ribose)

- nitrogenous base attached to ribose

Term
DNA molecule
Definition
is actually a double stranted polymer, with the two strands held together by hydrogen bonds between the complementary bases of the two strands. the two estrands for a helix, so the DNA is a double helix.
Term
RNA molecule
Definition
it is a sequence of bases complementary to the sequence of a single gene in the DNA. There are 3 major types of RNA, all of them have roles in protein synthesis.
Term
DNA synthesis
Definition
is called DNA replication and only occurs during S phase. the DNA is stable.
Term
cell aging
Definition
a special enzyme (telomerase) is required to replicate the telomere (end of the chromosomes gradually shorten with each.
Term
RNA synthesis
Definition
is called transcription, and occurs in the nucleus throughout interphase. the enzyme is an RNA polymerase
Term
types of RNA:

ribosomal RNAs (rRNAs)

Definition
ribosomal RNAs (rRNAs) make up about 50% of the ribosome, a large complex of proteins and rRNAs which is resposible for directing protein synthesis and making covalent peptide bonds
Term
type of RNA

transfer RNAs (tRNA)

Definition

deliver the amino acids for protein synthesis.

* one binds the correct amino acid

* second matches up with the corret codon.

 

the anticodon of the tRNA is a three base sequence that base pairs with the codon.

Term
Protein syntesis
Definition
 called translation
Term
Genetics
Definition
deals with the inheritance of genes and chromosomes from one's parents. Most of the genetic problems involve mRNA genes, since problem with rRNA or tRNA genes would be fatal at conception
Term
polymorphic
Definition
Most mRNAs and their proteins are polymorphic (several different forms: this variation is good, since different forms of the protein may function better in different environments.
Term
alleles
Definition

 

 various forms of one gene are called alleles. the ABO blood group represents three alleles of a single gene. there are A, B and O alleles

Term
homozygous
Definition
in one individual, if both copies of a gene are the same, they are said to be homozygous, for the alleles
Term
heterozygous
Definition
if the 2 copies are different alleles, then the person is heterozygous
Term
genotype
Definition
the alleles you inherit are your genotype, which determines your anatomy and physiology (your phenotype
Term
genetic disease
Definition

 sometimes one allele may produce a form of the protein which may not work correctly ( or not at all) and have a niceable affect on the cell and the organism. these are called genetic disease

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