Shared Flashcard Set

Details

NutriSci Midterm 2
2nd midterm for NutriSci 10 at UC Berkeley
109
Other
Undergraduate 3
03/04/2012

Additional Other Flashcards

 


 

Cards

Term
Energy Balance
Definition
E in = E out
Term
Positive Balance
Definition
E in > E out
Term
Negative Balance
Definition
E in < E out
Term
Bomb Calorimeter
Definition
Burn food inside water to see how much water temperature is raised.
Term
What are 4 examples of how to get energy in?
Definition
Carbohydrate
Protein
Fat
Alcohol
Term
What are 4 ways to get Energy out?
Definition
1. BMR - Basal Metabolic Rate
2. PA - Physical Activity
3. TEF - Termic effect of food
4. NEAT - Nonexercise activity thermogenesis
Term
What is BMR - Basal Metabolic Rate?
Definition
energy required to maintain basal (rest) functions of the body

Involuntary Activites: respiration, circulation, body temp, new cells/hormones, nerve signals, fluid balance

60-70% of TEE
Term
What are determinants of BMR?
Definition
LBM - Lean Body Mass
age
gender
growth
healing
Term
How do you change your BMR?
Definition
Increase: building or maintain LBM
Decrease: energy restricted diets
Term
What is TEF? (Thermic Effect of Food)
Definition
energy used in food digestion, absorption, transport and storage of nutrients

5-10% of TEE

higher for carbs and protein than for fat
Term
What percentage of TEE is PA? (Physical Activity)
Definition
20-35% of TEE

couch potato: 10%
athlete in training: 50%
Term
What are the effects of more Physical Activity?
Definition
More energy expenditure during and after exercise.

higher LBM = higher BMR
Term
What is INDRECT calorimetry?
Definition
based on the energy metabolism equation:

Macronutrients + O2 -> ATP + CO2 + H2O + heat
Term
Energy Balance:
Energy In = Energy Out
Calories in Food = ___ + ___ + __ + ____
Definition
Calories in Food = BMR + TEF + PA + NEAT
Term
What range of BMI does disease risk increase?
Definition
<18.5 or >30
Term
What does BMI NOT take into account?
Definition
Muscle mass and bone size.
Term
What are some ways to measure LBM and Fat Mass?
Definition
fat folds
underwater weighing
bod pod
etc.
Term
Abdominal fat increases the risk of ________ _________.
Definition
chronic disease
Term
What is the waist-to-hip ratio of men and women? Waist circumference?
Definition
Men > 0.90 waist: > 40 in.
Women > 0.80 waist: > 35 in.
Term
Where is extra fat stored?
Definition
adipose tissue
Term
What is the percentage of Americans overweight or obese?
Definition
65%
Term
What are the 2 things and how much do they contribute to body fat?
Definition
Nongenetic factors = 75%
Genetic heritage = 25%
Term
What is the thrifty gene theory?
Definition
Genes conserve energy and expend less energy. Useful when starvation was a problem.
Term
What is Set-point Theory?
Definition
Body will try to maintain a set body weight

High energy intake = higher BMR and higher TEF (fidgeting)

Low Energy Intake = lower BMR
Term
What is leptin deficiency? What does it cause?
Definition
This is genetic where child is born with a normal weight, but obesity begins in infancy.
Body fat = 57% when normal is 20%

Leptin produced to prevent overeating
Term
What are 2 environment things that can cause obesity?
Definition
Overeating: fast-food, eat meals outside of home = larger servings
Physical inactivity: TV, video games
Term
How do you eat less?
Definition
eat small portions
choose lower energy density foods
consume enough water
minimize empty calories
Term
Ghrelin and NPY stimulate more or less food intake?
Definition
Ghrelin is from t he gut
NPY is from the hypothalamus

Both stimulate more food intake
Term
ATP
Definition
Primary energy that we burn, made from glucose, fatty acids, amino acids.
Term
ATP made of?
Definition
adenosine+3 phosphate groups
Term
how does glucose enter the cell?
Definition
facilitated active transport
Term
How is glucose metabolized, then formed acetyl-CoA
Definition
Carbs->glucose->pyruvate(forms cytoplasm)->acetyl-CoA
Term
glycolysis
Definition
only 3 carbons, so glucose forms 2 ATP and 2 pyruvate, also NADH(reduced form)
Term
cytosol to mitochondria
Definition
pyruvate will be converted to Acetyl CoA, two carbons form CO2(side product), while the others form acetyl Coa, also form more NADH
Term
TCA(tribiocylic acid) Cycle
Definition
produces CO2, GTP(ATP), NADH+FADH, cycle after CoA formed
Term
Oxidative phosphorylation
Definition
electron transport chain generates oxidized NAD&FAD, ATP(lots),Water. NADH gets oxidized where it loses electrons
Term
how are fatty accids metabolized
Definition
triglyceride-> breaks down to glycerol+fatty acids though lipolysis->pyruvate or B-oxidation-> acetyl Coa-> TCA cycle
Term
why do fatty acids provide more calories per gram than glucose
Definition
fatty acids have more carbon, can yield more acetyl CoA
Term
ketone synthesis
Definition
if not enough carbs, body forms acetoacetate(ketone bodies), backup plan if you are starving
Term
ketones
Definition
used for energy when there is deficiency, converted back to acetyl coa, but it is slow because lack of oxalocetate from low glucose. ketones spare protein, brain can run on energy from ketones. ketones lost in urine and breath. Inefficient use of energy, compared to acetyl Coa produced from beta oxidation
Term
protein metabolism
Definition
deamination
Term
How do feeding and fasting affect metabolism?
Definition
fed state-amino acids+glucose-> excess energy is stored/converted as fat
fasting short-term(between meals and overnight)-liver glycogen maintains blood glucose levels for energy, gluconeogensis to maintain glucose levels for blood and brain, FA for energy.
Prolonged fast(2+)-more fatigued, BMR goes down, rely on fatty acids that form ketones instead because no glucose, gluconeiogensis made from protein
Term
What is the daily required intake for water for men?
Definition
3.7L/day
Term
What's the DRI for water for women?
Definition
2.7L/day
Term
What is the general guideline for the amount of water to drink per day?
Definition
8 cups a day
Term
What are the 2 extracellular electrolytes?
Definition
Na+ and Cl-
Term
What is an example of an intracellular electrolyte?
Definition
K+
Term
What is the function of electrolytes?
Definition
regulate fluid balance
Term
vitamin A
Definition
retinoids
-retinol is vitamin A
-retinal used for visual cycle,95% of retinol
-retinoic acid other body functions,5% of retinol
Term
xerophthalmia
Definition
deficient vitamin A causes this
Term
retinoic acid effects
Definition
reproduction, nervous system, epithelia(skin), immune function
Term
retinal
Definition
retinoid for eyes, needed to be able to see light. most of retinol is converted to retinal.
Term
RDA of vitamin A, and UL
Definition
RDA: 0.3-1.3 mg
UL: 100fold>RDA in adults, 20 fold for children, 10 fold for chronic intake
Term
vitamin storage, retinol processing
Definition
retinol is split into retinoic acid and stored in liver
Term
Vitamin D
Definition
chloecalciferol-no need for vitamin D if adequate exposure to sunlight
Term
Vitamin A effect on testes
Definition
makes you sterile and you can't remember things
Term
cystic acne
Definition
cured with reinoid, but when taken during pregnancy causes birth defects
Term
psoriasis vulgaris
Definition
skin disease, can be treated with retinoids
Term
effects of atRA(renova)
Definition
gets rid of wrinkles
Term
Thiamin
Definition
Vitamin B1, coenzyme for CHO metabolism, energy production and nerve function
Term
Food sources for thiamin?
Definition
Pork, enriched grains
Term
Riboflavin
Definition
vitabin B2, sensitive to light, coenzyme involved in providing energy from CHO,fat and protein
Term
Sources of riboflavin
Definition
milk,meats, enriched grains
Term
Beriberi
Definition
thiamin deficiency, fatigue and nerve damage
Term
Niacin
Definition
vitamin B3 coenzyme involved in providing energy from fat and protein
Term
Pellagra
Definition
niacin deficiency, dermatitismdiarrhea, dementia
Term
sources of niacin?
Definition
meat,fish,poultry,enriched grains
Term
Vitamin B6
Definition
essential for gluconeogensism ATP production and neurotransmitter synthesis
Term
Sources of vitamin B6
Definition
chicken, fish(tuna), whole grains
Term
Pantothenic acid
Definition
coenzyme required for ATP production from fat, protein, CHO
Term
Biotin
Definition
coenzyme in metabolism and in converting fats+glucose
Term
coenzyme
Definition
small organize molecule that is necessary to activate many types of enzymes
Term
What are the main functions of water soluble vitamins?
Definition
coenzymes that help metabolize fat, protin, and CHO into energy
Term
Good sources of folate?
Definition
enriched grains, leafy green veggies, legumes, supplements
Term
good sources of vitamin B12
Definition
dairy products, eggs,meats, poultry
Term
Folate
Definition
vitamin used for DNA synthesis and red blood cell synthesis
Term
Vitamin B12
Definition
same function as B12
Term
Folate Deficiency
Definition
macrocytic anemia-cells unable to divide and abnormally large cells
Term
Vitamin K
Definition
blood clotting
blood vessel repair
bone density
preventing soft-tissue calcification
Term
TCA cycle
Definition
produces CO2,ATP,NADH+FADH
oxaloacetate+acetyl CoA form citrate to start the cycle
Term
aerobic metabolism
Definition
pyruvate modified to produce Acetyl CoA, NADH+H+, CO2
Term
Electron Transport Chain
Definition
produces lots of ATP, oxidized NAD&FAD, Water
Term
chylomicrons
Definition
carries TG
Term
where is TG stored?
Definition
adipose tissue
Term
lipase
Definition
separation of TG into FA+glycerol
Term
glycerol
Definition
turned into pyruvate then acetyl CoA->TCA
Term
beta-oxidation
Definition
converts FA to acetyl Coa
Term
oxaloacetate
Definition
produced from TCA cycle , and is needed to continue the TCA cycle. NEED CARBS, IF NO CARBS AVAILABLE THEN KETONE BODIES FORM
Term
NADH+FADH
Definition
provide electrons to the ETC, NADH gets oxidized, loses hydrogen, to help ATP
Term
homocysteine
Definition
increases CVD risk factor, increases with low intake of B12, folate or B6
Term
folate deficiency
Definition
spina bifida
Term
oxidation
Definition
atom loses an alectron
Term
reduction
Definition
atom gains an electron
Term
vitamin c
Definition
antioxidant, products WBC from oxidation, enhances immune function, protext lung cells from oxidation, protects LDL from oxidation, regenerates vitamin E
Term
vitamin c addition function
Definition
assists in synthesis of collagen, enhances iron absoprtion
Term
vitamin C deficiency
Definition
scurvy: bleeding gums
weakened blood vessels
-pinpoint hemorrhages
-bruising
bone and joint aches
bone fractures
poor wound healing
Term
neural tube
Definition
needs folate for formation
Term
where is calcium absorbed?
Definition
intenstines
Term
calcitriol
Definition
vitamin D is converted to this , hormone that induces intestine to absorb Ca
Term
Vitamin D deficieny
Definition
rickets-softening of bones in children, osteomalacia-normal structure, not enough calcium
osteoporosis-old age, both low
Term
vitamin D RDA
Definition
5-15ug/day
Term
vitamin K functions
Definition
essential for activating proteins required for:
blood clotting
blood vessel repair
bone density
preventing soft-tissue calcification
Term
Vitamin E
Definition
most potent fat soluble antioxidant
protects polyunsaturted FA from oxidative damage
protects membranes and LDL from oxidative damage
Term
RDA for thiamin
Definition
1.2
Term
collagen
Definition
major protein in connective tissue, need vitamin C as a coenzyme
Term
ADH
Definition
antidiuretic hormone, signals kidneys to reabsorb water to reprosuce
Term
hypoantremia
Definition
water intoxication(too much water)
Term
renin-angiotensin II-aldosterone system
Definition
reabsorb Na and CL and water in reponse to deacreased BV
Term
pernicious anemia
Definition
b12 deficieny, parietal cells that produce IF are destroyed
Supporting users have an ad free experience!