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Nutrition Across the lifespan
Chapters 1-6
36
Health Care
Undergraduate 2
03/01/2013

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Term
Nutrients
Definition
Term
Vitamins (14 total)
Definition
Organic, chemical substances which perform important and specific functions in the body and are required in very small amounts (micronutrient)
Term
Fat-soluble Vitamins
Definition
Found in lipid portions of food, stored in body fat and the liver
- digested and absorbed with dietary fat
Term
Water-Soluble Vitamins
Definition
Carried in aqueous part, not stored in the body
- Vitamins C and B Complex: 1,thiamin... 2,riboflavin... 3,niacin... 4,folate... 5,Pantothenate... 6,pyridoxine... 7,Biotin... 8,B12... 9,choline
(Excess consumption is excreted
Term
Minerals (15 required)
Definition
Inorganic elements that have specific roles in the body. Consist of one atom and carry a charge, they are micronutrients
- Aid in conducting electrical current to stimulate contraction of muscles, nerve impulses, and htey are vital for maintaining acid/base equilibrium
Term
Macronutrients
Definition
Required in large amounts, provide energy
1.Carbohydrates
2. Proteins
3.Lipids(triglycerides=95% of fat consumption, 5% sterols/phospholipids
4.Alcohol (more energy/g than carbs)
Term
Gonadotropin-Releasing Hormone (GnRH)
Definition
released by Hypothatlamus
- Stimulates release of FSH & LH
Term
Follicle-stimulating hormone (FSH)
Definition
secreted by Pituitary
- stimulates maturation of ova & Sperm
Term
Leutinizing hormone (LH)
Definition
Pituitary
- stimulates secretion of estrogen, progesterone, testosterone
Term
Estrogen
Definition
Ovaries
- first stimulates then inhibits GnRH during the menstrual cycle
- stimulates thickening of uterine wall during cycle
- born with eggs - about half million ova per ovary remain by beginning of puberty
-fat cells produce estrogen - onset of puberty related to % body fat
Term
Progesterone
Definition
Ovaries
- prepares uterus for fertilized egg and to maintain a pregnancy
- stimulates cell division of fertilized egg
-inhibits action of testosterone
Term
Testosterone
Definition
Testes
- stimulates maturation of males sex organs and sperm
- stimulates formation of muscle
-some estrogen produced
for those sperm - gotta be have numbers, good shape/morphology and good motility,swimmers
-making sperm continuously (70-90 day lifespan)
Term
leptin
Definition
produced in fat cells - increases energy
losing weight -> decreased leptin -> decreased FSH & LH -> decreased estogen/testosterone production
Term
Too little/much body fat on estrogen
Definition
too little - decreased estrogen
too much - increased estrogen
- either way its off balance
Term
Celiac Disease (KNOW)
Definition
Immune response to protein in wheat (gliadin in gluten), rye and barley
- decreased reserves causes decreased estrogen and fertility
- intestinal problem leads to under nutrition (folate, iron, vit. AED
-gluten free diet, only cure
Term
Carotenemia
Definition
Excessive carotenoids/carotenes consumption of ~12 mg/d beta carotene for 6+ weeks may lead to amenorrhea and mestrual dysfunction.. unknown cause
- Vit. A can lead to birth defects
-please consume >5000 IU/D retinol
-RDA = 3500 IU/d or 700 mcg/d
Term
Zincs role in reproduction
Definition
cofcators for enzymes involved in testosterone production
- synthesis and DNA replication/cell division
- keeps sperm healthy
Term
LOW antioxidants?
Definition
increased oxidative damage of sperm DNA and PUFA in semen
- can lead to decreased motility and morphology
=also heavy metal exposure like lead, mecury, cadmium, manganese will decrease sperm prodction, motility, and shape, so definitely avoid those..
alcohol has similar effects!!!
Term
Ubiquitous environmental contaminants on fertility
Definition
Phtalates=chemicals used in plastic production
-DDT (insecticide)
-PCBS (industrial compounds and byproducts)
- all shown to cause cancer in animals
Term
Mother underweight?
Definition
increased rish of Low birth weight and pre term delivery
-increased risk of complication to mother
Term
mother overweight?
Definition
increase rish of neural tube defects, excess fat on newborn, and complication to mother
Term
alcohol and pregnancy
Definition
increased rish of fetal alcohol spectrum
- it disrupts placenta function which causes decreased glucose and oxygen to the baby
- changes cgnitive ability, behavior and body/facial features
Term
folate & NTD
Definition
in low folate early in pregnancy, while neural tube is developing then theres an increased rish for a NTD
- it is formed in the first 21 days after conception
Term
Anencephaly
Definition
absence of brain or spinal cord
Term
spina bifida
Definition
spinal cord fails to close, so spinal fluid collect in the fap during pregnancy
low b12 =low folate = incresed risk, and oral contraceptives cause this low b12
Term
iron deficiency
Definition
increased risk of preterm
-increased risk of anemia in infant
- difficult to catch up once low
- about half women have inadequate stores
Term
vitamin A
Definition
too much can lead to facial and heart abnormalities
Term
diabetes and preconception
Definition
uncontrolled in early pregnancy = increased risk of DM in offspring
- gestational DM increaed mother's risk for T2D later in life
- inreased risk of fetal deformities
- increased BW
Term
insulin resistance - effects on pregnancy
Definition
increased:
- strain on pancrease
-risk of gestational DM
-LDL-C -> decreased HDL
- insulun may increase fat storage
- possibility of larger baby
- oxidative stress
*intervention*
=weight control, activity, complext CHO, low glycemic index, lower saturated FA's
Term
Diabetes
Definition
elevated BG above normal fasting (>126 mg/dL)
=uncontrolled may decrease fertility
=T2 has increased risk of polycystic ovary syndrome which is the leading cause of female infertility
*** increased birth weight of paby, increased fat deposition, possibly increased risk for DM later, and congential abnormalities
Term
T1D
Definition
no insulin produced
Pancreas - destroyed beta cells (autoimmune response)
risk factors - unsure but the pancreas is damaged somehow
Term
T2D
Definition
Decreased sensitivity to insulin and not enough produced
Pancreas - beta cells still work but no adequately
-risk factors - genetic, overweight, abdominal obesity and not likely increased sugar intake
Term
polycystic ovary syndrome
Definition
affects 10% of reproductive-aged women
risk factors=insulin resistance and genetics
- lowers fertility
-causes large baby, secondary to increased BG
-INTERVENTION = increased physical activity, complext CHO, n-3 FA's
and decreased CHO to 45-50% cals
Term
NUTRITION IS KEY IN:
Definition
sperm viability and motility, ovulation and viability, successful fertilization, health of pregnant woman, health of embryo/fetus, pregnancy outcome
Term
Shifting nutritional needs
Definition
early maternal blood volume, later maternal mammary glands, early fetal CNS, later fetal skeletal system calcification, develops skeleton throughout, later fetal iron stores, later fetal fat and nutrient accumulation/storage
Term
nutrition programming
Definition
exposure to certain possibly deficient levels of energy and nutrients changes the function of genes which may affect metabolism and risk of chronic diseases much later in life
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