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Organic, chemical substances which perform important and specific functions in the body and are required in very small amounts (micronutrient) |
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Found in lipid portions of food, stored in body fat and the liver - digested and absorbed with dietary fat |
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Carried in aqueous part, not stored in the body - Vitamins C and B Complex: 1,thiamin... 2,riboflavin... 3,niacin... 4,folate... 5,Pantothenate... 6,pyridoxine... 7,Biotin... 8,B12... 9,choline (Excess consumption is excreted |
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Inorganic elements that have specific roles in the body. Consist of one atom and carry a charge, they are micronutrients - Aid in conducting electrical current to stimulate contraction of muscles, nerve impulses, and htey are vital for maintaining acid/base equilibrium |
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Required in large amounts, provide energy 1.Carbohydrates 2. Proteins 3.Lipids(triglycerides=95% of fat consumption, 5% sterols/phospholipids 4.Alcohol (more energy/g than carbs) |
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Gonadotropin-Releasing Hormone (GnRH) |
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released by Hypothatlamus - Stimulates release of FSH & LH |
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Follicle-stimulating hormone (FSH) |
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secreted by Pituitary - stimulates maturation of ova & Sperm |
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Pituitary - stimulates secretion of estrogen, progesterone, testosterone |
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Ovaries - first stimulates then inhibits GnRH during the menstrual cycle - stimulates thickening of uterine wall during cycle - born with eggs - about half million ova per ovary remain by beginning of puberty -fat cells produce estrogen - onset of puberty related to % body fat |
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Ovaries - prepares uterus for fertilized egg and to maintain a pregnancy - stimulates cell division of fertilized egg -inhibits action of testosterone |
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Testes - stimulates maturation of males sex organs and sperm - stimulates formation of muscle -some estrogen produced for those sperm - gotta be have numbers, good shape/morphology and good motility,swimmers -making sperm continuously (70-90 day lifespan) |
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produced in fat cells - increases energy losing weight -> decreased leptin -> decreased FSH & LH -> decreased estogen/testosterone production |
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Too little/much body fat on estrogen |
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too little - decreased estrogen too much - increased estrogen - either way its off balance |
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Immune response to protein in wheat (gliadin in gluten), rye and barley - decreased reserves causes decreased estrogen and fertility - intestinal problem leads to under nutrition (folate, iron, vit. AED -gluten free diet, only cure |
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Excessive carotenoids/carotenes consumption of ~12 mg/d beta carotene for 6+ weeks may lead to amenorrhea and mestrual dysfunction.. unknown cause - Vit. A can lead to birth defects -please consume >5000 IU/D retinol -RDA = 3500 IU/d or 700 mcg/d |
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Zincs role in reproduction |
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cofcators for enzymes involved in testosterone production - synthesis and DNA replication/cell division - keeps sperm healthy |
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increased oxidative damage of sperm DNA and PUFA in semen - can lead to decreased motility and morphology =also heavy metal exposure like lead, mecury, cadmium, manganese will decrease sperm prodction, motility, and shape, so definitely avoid those.. alcohol has similar effects!!! |
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Ubiquitous environmental contaminants on fertility |
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Phtalates=chemicals used in plastic production -DDT (insecticide) -PCBS (industrial compounds and byproducts) - all shown to cause cancer in animals |
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increased rish of Low birth weight and pre term delivery -increased risk of complication to mother |
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increase rish of neural tube defects, excess fat on newborn, and complication to mother |
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increased rish of fetal alcohol spectrum - it disrupts placenta function which causes decreased glucose and oxygen to the baby - changes cgnitive ability, behavior and body/facial features |
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in low folate early in pregnancy, while neural tube is developing then theres an increased rish for a NTD - it is formed in the first 21 days after conception |
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absence of brain or spinal cord |
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spinal cord fails to close, so spinal fluid collect in the fap during pregnancy low b12 =low folate = incresed risk, and oral contraceptives cause this low b12 |
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increased risk of preterm -increased risk of anemia in infant - difficult to catch up once low - about half women have inadequate stores |
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too much can lead to facial and heart abnormalities |
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diabetes and preconception |
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uncontrolled in early pregnancy = increased risk of DM in offspring - gestational DM increaed mother's risk for T2D later in life - inreased risk of fetal deformities - increased BW |
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insulin resistance - effects on pregnancy |
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increased: - strain on pancrease -risk of gestational DM -LDL-C -> decreased HDL - insulun may increase fat storage - possibility of larger baby - oxidative stress *intervention* =weight control, activity, complext CHO, low glycemic index, lower saturated FA's |
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elevated BG above normal fasting (>126 mg/dL) =uncontrolled may decrease fertility =T2 has increased risk of polycystic ovary syndrome which is the leading cause of female infertility *** increased birth weight of paby, increased fat deposition, possibly increased risk for DM later, and congential abnormalities |
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no insulin produced Pancreas - destroyed beta cells (autoimmune response) risk factors - unsure but the pancreas is damaged somehow |
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Decreased sensitivity to insulin and not enough produced Pancreas - beta cells still work but no adequately -risk factors - genetic, overweight, abdominal obesity and not likely increased sugar intake |
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polycystic ovary syndrome |
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affects 10% of reproductive-aged women risk factors=insulin resistance and genetics - lowers fertility -causes large baby, secondary to increased BG -INTERVENTION = increased physical activity, complext CHO, n-3 FA's and decreased CHO to 45-50% cals |
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sperm viability and motility, ovulation and viability, successful fertilization, health of pregnant woman, health of embryo/fetus, pregnancy outcome |
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Shifting nutritional needs |
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early maternal blood volume, later maternal mammary glands, early fetal CNS, later fetal skeletal system calcification, develops skeleton throughout, later fetal iron stores, later fetal fat and nutrient accumulation/storage |
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exposure to certain possibly deficient levels of energy and nutrients changes the function of genes which may affect metabolism and risk of chronic diseases much later in life |
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