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Ocular Embryology
N/A
24
Other
Graduate
01/04/2012

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Cards

Term
What is the order the cells in the neural retina develops?
Definition
Ganglion, horizontal, cones, amacrine, bipolar, rods, Muller
Term
T or F. The macular area is the first to begin differentiation and the first to complete development.
Definition
False. Foveal maturation is not complete until approximately 4 years of age
Term
The hyaloid artery supplies blood to what structure.
Definition
the posterior vascular tunic of the lens, the annular vessel to the ONH, annular vascular tunic of the lens

-> at the 7th month there should be no blood flow to any of these structures, the amount of glial tissue left defines the extent of the optic cup
Term
The outer layer of the optic cup becomes what?
Definition
RPE, Outer pigmented CB epithelium, Anterior iris epithelium
Term
What is the most common intraocular(primary) malignancy in children, why does it occur?
Definition
Retinoblastoma, mutations to the Rb tumor suppressor gene
Term
Where is the thickest basement membrane in the body?
Definition
lens capsule
Term
The lens capsule blocks what from entering the lens?
Definition
hemoglobin and albumin
Term
What types of junctions are found in the anterior lens epithelium?
Definition
gap junctions
Term
Where is the germative zone of the lens?
Definition
anterior lens epithelium
Term
what is the oldest area of the lens called
Definition
the embryonic nucleus
-> highest index of refraction
Term
How does the lens epithelium give the fibers nutrition?
Definition
pinocytosis
Term
when does corneal epithelium develop
Definition
5th/6th month
Term
what forms the corneal epithelium
Definition
lens vesicle-> surface ectoderm
Term
when does the rest of the cornea develop
Definition
4th month
Term
what forms the rest of the cornea
Definition
neural crest cells
Term
when does the lacrimal gland fully develop
Definition
age 4
Term
what is made from surface ectoderm
Definition
corneal epithelium, lens, lacrimal gland, lacrimal sac, canaliculi, nasolacrimal duct, caruncle, epithelium of meibomian, zeis, moll, krauss, and wolfring glands, conj. epithelium
Term
lens zonular fibers are derived from what
Definition
tertiary vitreous
Term
what is made from neural ectoderm
Definition
retina, rpe, neuroglia, epithelium of iris, epithelium of CB, sphincter and dilator muscles, optic nerve fibers
Term
what comes from neural crest
Definition
all corneal layers but epithelium, TM, iris stroma, CB stroma, sclera, choroid, vitreous
Term
irregular iridocorneal adhesions occur as what, and what disease is this called
Definition
abnormal neural crest cell development, Axenfeld's anomaly
Term
congenital glaucoma sign
Definition
corneal haze, corneal edema, buphthalmos, Haab's striae, optic nerve damage, high myopia, possible subluxation of lens
Term
what comes from mesoderm
Definition
EOMs, endothelium of blood vessels, orbiuclaris oculi, levator palpebrae, Muller's muscle
Term
what forms connective tissue of the globe and orbit
Definition
neural crest and mesoderm
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