Term
How do you evaluate a case of suspected Septic Arthritis |
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Definition
Cell Count
Gram Stain
Culture
Blood Culture
Crystals
X-Ray |
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Term
Do septic arthritis patients always have high WBC's in the synovium |
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Definition
No, may not if peripheral counts are low(cancer) |
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Term
When can Septic arthritis present as polyarticular Arthritis |
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Definition
Preexisting Polyarticular disease
IV Drug User |
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Term
What is the treatment for Septic Arthritis |
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Definition
Gram(+): Vancomycin intial then narrow
Gram(-): Cephalosporin +/- Aminoglycoside
Serial drainage as necessary |
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Term
What are the primary and secondary etiologies of Goat |
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Definition
Overproduction: Secondary(myeloproliferative disease), Primary: Idio
Underexcretion: Secondary(Renal Defect), Primary: Idio |
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Term
How do you diagnose gout and what lesions are highly suggestive? |
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Definition
Dx:Visualization of Urate Crystals(birefringent)
Acute Gouty Arthritis, Tophi, Uric Acid Stones |
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Term
How do you treat the acute gouty attack vs hyperuricemia? |
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Definition
Acute: NSAIDs or Intra-articular/oral Steroids
Hyperuricemia: Probenecid(Need Good GFR)
Allopurinol: Xanthine Oxidase Inhibitor (Renal excretion)
Febuxostat: XO Inhibitor (Hepatic Elimination)
Rasburicase: Urate Oxidase used for Tumor lysis syndrome |
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Term
What is the threshold for Hyperuricemia? |
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Definition
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Term
What is pseudogout and what patient population is it typically seen in |
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Definition
Deposition of Calcium Pyrophosphate Dihydrate in cartilage
Typically seen in people >65 |
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Term
Characteristic Symptoms of Systemic Onset JIA |
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Definition
Quotidian Pattern Fever
Evanescent Rash
Lymphadenopathy, Hepatosplenomegaly
Thrombocytosis, Leukocytosis, Anemia, CRP
Serositis: Pericarditis, Chest Pain when lying down, ST elevation, and T wave inversion |
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Term
Complications of Systemic Onset JIA
and Treatment |
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Definition
Marophage activation Syndrome:
Liver Failure with Encephalopathy, Bruising, Mucosal bleeding, low ESR(like DIC), Leukopenia, Anemia, Thrombocytopenia
Treatment: High dose Methylpredisone and Cyclosporin A
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Term
Typical presentation of Oligo JIA |
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Definition
<4 joints involved
(20%)Arthritis with Uveitis
Morning Stiffness, Aching Stretching
No Systemic Signs
ANA |
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Term
What screening must be done on every patient with oligo JIA? |
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Definition
Eye Exam for Anterior Uveitis: Uveitis indicates a worse prognosis |
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Term
Complications of Oligo JIA |
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Definition
Leg Length Discrepancies
Micrognathia
Brachydactyly
Atlantoaxial subluxation
Baker's Cyst(Popliteal Cyst) |
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Term
Girls who are ANA positive are at greater risk for developing what complication along with their JIA |
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Definition
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Term
What are the uveal complications associated with JIA |
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Definition
Cataracts
Glaucoma
Band Keratopathy
Posterior Synechiae-Iris adheres to the Lens
Visual Loss |
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Term
Common presentation of Enthesitis-Related Arthritis |
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Definition
Lower Extremity
SI Joint
Patella-10, 2, and 6 o'clock
Achilles
Tarsitis-Metatarsals, Plantar Fasciitis |
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Term
What is the common presentation of Juvenile Psoriatic Arthritis and how is it treated |
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Definition
Sausage fingers
Nail Pitting
Tx: Nsaids, Steroids, Methotrexate, Biologicals, Articular Steroids, Physical Therapy, Surgery
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