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How many bones are in the axial skeleton? |
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How many bones are in the appendicular skeleton? |
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Functions of the Skeletal System: |
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Definition
1. Support 2. Storage of minerals 3. Blood cell production 4. Protection 5. Leverage |
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1. Flat 2. Sutural 3. Long 4. Irregular 5. Sesamoid 6. Short |
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Tunnel providing access to marrow cavity |
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Carry blood to/from metaphysis Connects to epiphyseal arteries/veins |
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Smaller blood vessels (supply superficial osteons) Lymphatic vessels (collect lymph from bone and osteons) Sensory nerves (innervate diaphysis, medullary cavity, and epiphyses) |
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Mature bone cells that cannot divide Most numerous bone cell type Maintain protein and mineral content of adjacent matrix Occupy lacunae |
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Produce new bony matrix Become osteocytes once surrounded by bony matrix |
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Mesenchymal (stem) cells that produce cells that differentiate into osteoblasts Important in fracture repair |
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Remove and remodel bone matrix Giant cells with 50+ nuclei Release acids and proteolytic enzymes to dissolve matrix and release stored minerals |
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Calcium phosphate (Ca3(PO4)2) accounts for ___ bone weight. |
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Outer and inner surfaces of compact bone layer |
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Fill spaces between osteons |
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Contain central canals (parallel to bone surface) Connected by perforating canals (perpendicular) |
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Fibrous outer layer Cellular inner layer |
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Isolate bone from surrounding tissues Route for blood and nervous supply Actively participate in bone growth and repair |
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Reduction in growth hormone leads to reduced epiphyseal cartilage activity and short bones Rare due to treatment with synthetic growth hormone |
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Definition
Epiphyseal cartilage grows unusually slowly Limbs are short Trunk is normal size |
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Excessive cartilage formation at epiphyseal cartilage Causes long, slender limbs Other connective tissue abnormalities cause cardiovascular issues |
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Definition
Overproduction of growth hormone before puberty |
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Fibrodysplasia ossificans progressiva (FOP) |
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Definition
Gene mutation that causes bone deposition around skeletal muscles |
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Definition
Growth hormone levels rise after epiphyseal plates close Bones get thicker |
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Calcium levels of activity controlled by: |
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Definition
Intestines, Bones, Kidneys |
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Crack or break due to extreme mechanical stress Most heal as long as blood supply and cellular parts of periosteum and endosteum survive |
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