Term
| What is the general concept of the Sensory Conflict theory? |
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Definition
| There is a mismatch between the senses (visual, vestibular and proprioception) |
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Term
| What receptors are the target for prevention of motion sickness? |
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Definition
| Histaminic and Muscarinic |
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Term
| What are some non-pharmacologic ways to treat motion sickness? |
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Definition
Don't read
Avoid unnecessary head movements
Ensure adequate ventilation
avoid heavy greasy meals or unpleasant odors |
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Term
What is the MOA of antihistamines?
What pts must use these with caution?
What are the AE? |
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Definition
a) block H1 receptors on the vestibular system causing a decrease in nerve conduction
b) BPH, Narrow angle Glaucoma, Breathing problems
c) Sedation, anticholinergic effects |
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Term
| What are the OTC antihistamines used for motion sickness? |
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Definition
Meclizine
Cyclizine
Dimenhydrinate |
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Term
What is the age limit for meclizine?
Pregnancy Category?
When should it be taken? |
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Definition
a) not in children <12yrs
b) B
c) 1 hr prior to activity |
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Term
What is the age limit for cyclizine?
How should it be taken
When should it be taken? |
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Definition
a) not in children <6yrs
b) Chewable,1 tab Q6-8 hrs max 3 tabs/day
c) 1 hr before actitivy or at onset of symptoms |
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Term
What is the age limit for dimenhydrinate?
What is it chemically similar to?
When should it be taken? |
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Definition
a) not for children <2 yrs
b) diphenhydramine
c) 30-60 mins prior |
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Term
T/F
The Rx antihistamines have antimuscarinic properties |
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Definition
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Term
Promethazine
a) What is the black box warning
b) What are the dosage forms
c) Contraindications?
d) AE?
e) pregnancy category |
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Definition
a) not for use in children <2yrs
b) tabs, suppository
c)coma, lower resp tract symptoms
d) sedation, EPS, anticholinergic
e) C |
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Term
Scopolamine
a) MOA
b) Contraindications?
c) AE?
d) Caution in which patients? |
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Definition
a) block cholinergic transmission from vestibular system to higher centers in teh CNS
b) Hypersensitivity to scop., belladona alkaloids, narrow angle glaucoma
c) dry mouth, drowsiness, blurred vision, dilation of pupils
d) eldery, or with impaired liver/kidney function, seizures or psychosis, urinary bladder obstruction |
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Term
How should scopolamine be applied?
how long does its effects last?
who can use it?
excreted in breast milk?
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Definition
apply one patch to hairless area behind ONE ear 4 hrs before activity.
3 days
only for adults
yes |
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