Shared Flashcard Set

Details

Parkinson's
Exam 2
39
Other
Professional
01/17/2012

Additional Other Flashcards

 


 

Cards

Term
Max dose Carbidopa
Definition
200mg/day
Term
Max dose Levodopa
Definition
2000 mg/day
Term
Minimum Carbidopa to inhibit LAAD?
Definition
75mg
Term

Delayed On

No On

 

  • Characteristics
  • Solution
Definition

Delayed response or minimal response to previously adequit

  • Give on an empty stomach
  • Switch to IR/crush
  • Increase dose
  • Reduced dietary protein
  • Add DA agonist (Apomorphine)
Term

Wearing off

  • Characteristics
  • Solution
Definition

Decreased duration

  • Change to CR
  • Add MAO/COMT inhibitor
  • Add IR at the end
  • Oral liquid formulations
  • LA at PM to prevent awakening
Term

On/Off

  • Characteristics
  • Solution
Definition

Fluctuates good - poor movement

(Brain adapting to varying blood levels)

  • Add DA agonist
  • Change to CR
  • Add MAO/COMT inhib
  • NO drug holiday
Term

Dyskinesias

  • Characteristics
  • Solution
Definition

Abnormal jerking (Too much DA)

  • ↓DA, ↑ frequency or CR
  • Add amantadine

 

Term

Freezing

  • Characteristics
  • Solution
Definition

Unable to move lower extremities

  • ↑ Dose, agonist, MAOb
  • Gait modification (Walker)
Term

Dystonias

  • Characteristics
  • Solution
Definition

sustained muscle contractions AM (low DA)

  • Add DA agonist
  • CR HS
  • Baclofen
Term

Myoclonus

  • Characteristics
  • Solution
Definition

Repetative jerking PM

  • ↓ PM dose
  • Clonazepam (Benzodiazepine)
Term
Akathisia
Definition

restless feeling, restless leg

(wearing off of levodopa)

  • Add PM DA med
  • Clonazepam
Term
This DA agonist needs dose adjustment for renal impairment
Definition

Pramipexole

(Difficulty to P)

Term
This DA agonist needs a test dose, and pretreatment with what agent?
Definition

Apomorphine

pretreatment with Trimethobenzamide (Tigan)

(Antes de la Tigra)

Term
This DA agonist has a SE of pulmonary fibrosis
Definition

Bromocriptine

(Kryptonite)

Term
Which DA agonist can act as rescue therapy
Definition

Apomorphine

(Antes de muerto)

Term
Which class of drugs are best for treating drug induced PD
Definition

Anticholinergics

Amantadine

 

Term
Which drug classes are not intended for >75?
Definition

Anticholinergics

Amantadine

DA agonists

Term
Benztropine
Definition

(Cogentin)

Anticholinergic

Term
Trihexyphenidyl
Definition

(Artane)

Anticholinergic

Term
Selegiline
Definition

(Eldepryl, Zelapar)

MAO-B inhibitor

Term
Rasagiline
Definition

(Azilect)

MAO-B inhibitor

Term
Entacapone
Definition

(Comtan)

COMT Inhibitor

Term
Tolcapone
Definition

(Tasmar)

COMT Inhibitor

  • CNS & Periphery
  • Liver damage
Term
Bromocriptine
Definition

(Parlodel)

DA Agonist, ergot

  • Pulmonary fibrosis

 

Term
Ropinerole
Definition

(Requip)

DA Agonist

 

Term
Pramipexole
Definition

(Mirapex)

DA Agonist

  • Adjust for Renal
Term
Apomorphine
Definition

(Apokyn)

DA Agonist

  • Test dose
Term

Mild Motor disability

No Cognative

Definition
MAO-B inhibitor
Term

mild/Moderate Motor

No Cognative 

Definition
DA agonist
Term

Moderate/Severe Motor

Cognative

>75

Definition
L-Dopa
Term
Akinesia
Definition

Loss of normal muscle responsiveness

(Akon can pop lock)

Term
Akathisia
Definition

Sense of inner restlessness, constant movement

(Although I am sedated, I feel restless since they put a catheter in me)

Term
Bradykinesia
Definition

Difficulty initiating movement

 

 

Term
Dysarthria
Definition

Unclear pronunciation

(What are you saying Arthyr?)

Term
Dysphagia
Definition
Difficulty swallowing
Term
Hypomimia
Definition

"masked face"

expressionless

(I met my girlfriend Mimi at a mascarade party)

 

Term
Hypophonia
Definition
Quiet speech
Term
Dystonia
Definition

Sustained muscle contractions usually in the AM

(He sure has good muscle tone)

Term
Dyskinesia
Definition

Tremors or tics

(Kinetics)

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