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Part 1: Chapter 22
Early Brain Development
12
Other
Undergraduate 2
09/03/2014

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Term
notochord
Definition
defines the embryonic midline, and thus the axis of symmetry for the entire body
Term
neuroectoderm
Definition
the ectoderm that lies immediately above the notochord; gives rise to the entire nervous system
Term
neural tube
Definition
the cells that give rise to the brain, the spinal cord, & most of the peripheral nervous system
Term
neural stem cells
Definition
neuroectodermal precursor cells that are the progenitor cells of the neural tube; produces neurons, astrocytes, & ogliodendroglial cells
Term
floorplate
Definition
the cells at the ventral midline of the neural tube; a specialized strip of epithelial-like cells that send molecular signals to specify position & fate for the neuroectodermal precursors of the spinal cord & hindbrain
Term
roofplate
Definition
a narrow strip of neuroepithelial cells at the dorsal midline of the neural tube that differentiate dorsal cell groups
Term
neural crest
Definition
the dorsalmost limit of the neural tube (along most of its length); the region where the edges of the folded neural plate come together
Term
neural crest cells
Definition
fill the spaces between the neural tube, embryonic epidermis, & somites
Term
neuroblasts
Definition
immature nerve cells
Term
new stem cells arise from _____ divisions of neuroectodermal cells
Definition
symmetric
Term
postmitotic neurons are generated from cells that divide _____
Definition
asymmetrically
Term
epithelial-to-mesenchymal transition
Definition
the process by which neural crest cells downregulate expression of adhesive genes to allow for migration
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