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Part 1: Chapter 4
Ion Channels and Transporters
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Undergraduate 2
09/16/2014

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Term
voltage-gated ion channels
Definition
selectively permeable to each of the major physiological ions; respond to changes in the membrane potential
Term
SCN genes
Definition
Na+ channel genes
Term
CACNA genes
Definition
Ca2+ channel genes
Term
ligand-gated ion channels
Definition
type of ion channel that responds to chemical signals (ligands); less selective than voltage-gated
Term
what is the most important of the ligand-gated ion channels in the nervous system?
Definition
the class activated by binding neurotransmitters
Term
active transporters
Definition
generate & maintain concentration gradients for particular ions across the plasma membrane
Term
ATPase pumps
Definition
acquire energy directly from the hydrolysis of ATP; active transporter
Term
ion exchangers
Definition
exchange intracellular & extracellular ions; move one or more ions up its electrochemical gradient while taking another ion down its gradient
Term
co-transporters
Definition
carry multiple ions in the same direction; move one or more ions up its electrochemical gradient while taking another ion down its gradient
Term
electrogenic
Definition
a pump that generates an electrical currant that can hyperpolarize the membrane potential; ex) sodium-potassium pump
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