Term
| Clean room wall, ceiling and floors made of what ? |
|
Definition
| Non-porous cleanable surfaces |
|
|
Term
| How often is the laminar airflow and clean room equipment certified? |
|
Definition
|
|
Term
Room air is filtered through what kind of filter?
How much and of what size are the particles it filters? |
|
Definition
| HEPA filter removes 99.97% of particles 0.3 microns or larger |
|
|
Term
| What should vertical flow hoods be used for ? |
|
Definition
cyctotoxic agents, radioactive agents, antimicrobial agents.
Also preferred for community pharmacies. |
|
|
Term
Laminar flow hoods need to be what class?
What does this mean? |
|
Definition
Class 100
Means less than 100 particles of 0.5 microns or larger per cubic foot |
|
|
Term
How long should you wait before using the airflow hoods before work commences?
How long should you wait to use the hoods after cleaning? |
|
Definition
Leave hood running 30 minutes before work commences.
Do not use for 5 minutes after cleaning |
|
|
Term
|
Definition
| Don't wipe where air is coming from. eg. horizontal - don't wipe the back, vertical - don't wipe the top |
|
|
Term
Horizontal flow hood.
How far from the sides should the supplies be placed?
How far in should the technicians hands be inside the hood?
How should supplies be placed relative to eachother? |
|
Definition
3 inches from sides
tech's hands 6 inches inside hood
Supplies should be placed so that they do not block air flow to each other |
|
|
Term
Personnel involved in aseptic preparations
What they should do |
|
Definition
Wash hands with proper antibacterial
All non-sterile surfaces should be swabbed with alcohol, and left for 30 seconds.
Insert needles at a 45 degree angle |
|
|
Term
Dry Heat sterilization
Temperature ?
For how long?
For what ? |
|
Definition
Dry Heat sterilization
Temperature 160-170 Celc
For how long: 2-4 hours
For what: Glassware, fixed oils, glycerin, petrolatum, mineral oil, paraffin, glassware, surgical instruments, heat stable powders.
NON-AQUEOUS solutions. |
|
|
Term
Steam sterilization
Temperature ?
For how long?
What pressure?
For what ? |
|
Definition
Steam sterilization
Temperature 121 celc
For how long - 15 minutes
15-20 lbs of pressure
For what - Solutions SEALED in ampules, vials or bulk solutions, surgical instruments and dressing
DO NOT use for oil based preps, or MOISTURE sensitive preps. |
|
|
Term
Filtration sterilization
What is it used for ?
Size of bacterial filtration vs. HEPA ? |
|
Definition
Filtration sterilization
What is it used for - Heat sensitive materials (eg. hormones or proteins)
Size of bacterial filtration vs. HEPA: 0.22 microns vs. 0.33 microns |
|
|
Term
Gaseous Sterilization
Equipment?
Method/chemical?
Humidity requirement?
temperature & pressure ?
What is it used for?
What should it not be used for? |
|
Definition
Gaseous Sterilization
Equipment - Special oven with admission of gas and humidity
Method/chemical - ethylene oxide
Humidity requirement - 20% RH
temperature & pressure - 20-55 celc, 30 psi
What is it used for - Plastics, polymers, opthalmic preps, SQ, vaginal inserts, plastic syringe, tubing sets
What should it not be used for - Explosion hazard if use SOLUTIONS |
|
|
Term
Radiation Sterilization
Equipment?
Application? |
|
Definition
Radiation Sterilization
Equipment - Ultraviolet lamp, ionization, X-rays
Application - thermo labile powders |
|
|
