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Patho 2 test- HTN Drugs
descriptions of drugs
10
Medical
Undergraduate 3
10/15/2008

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Term
Narcan
Definition
Pain med
most common narcotic anatagonist

avaible as patch
reveres affects of narcotics in overdoses

RESP depression key less then 10 resp is indicator
Term
Morphine Sulfate
Definition
Opoid
Actions: Well absorbed high 1st pass rate
active metbolites fromed
exerts efforts thru opoid receptors n NS, inhibits substance P

AE's: resp, CNS dpression. Hypotension

Admin:IM,IV,PO, INTRATHCAL, PCA, TRansdermal, no ceiling effects

Treat pain early and regular
Term
Diuretics
Definition
hydroclorothiazide
First line in HTN
decrease vascular vol, increase NA and H2O excretions

AE's: hypoklameia, orthostaic hypotension
Term
Beta Blockers
Definition
Inderal
decrease hr and co, decrease rein release, decrease force of contractions, bronchodialte

AE's- neg inotropic, (decrease CO) Hypotension, bradycardia, bronchospams

Contradictions: Asthma, depression,bradycardia, hotension, hf

Nonselective block 1 and 2 more AE
B1 blockers decreased aes
Term
Ace Inhibitor
Definition
Pril
inhibit conversion agaiotensin 1 to 2
decrease vasoconstrition and aldosterone lvls, excrete na and water

Ae's: Headache fatigue, COUGH!!!, hypotension
Term
Alpha Blockers
Definition
coxazosin(cardura)
Arterial Vasodialtion
AE:palpittations, nervousness
DECREASE BP WITH 1ST DOSE SO START LOW!
Term
CENTRALLY ACTING VASODIALTOR
Definition
catapres
,inhibit sns stimulation--> dialtion of peripheral blood vessels- decrease PVR

AES:depression liver, vertgo, drowsiness
Term
Calcium channel Blockers
Definition
amlodipine
prvents ca from crossing cariac/vascular muscle cells-->dialtions, decreases force and contration, workload, bp

prvents constrcition of arterioles

decrease HR-slowed conduction of SA and AV

AES:ortho hypo, brady, headache
Term
Angiotensin II Blockers
Definition
Cogard
Block A-11 receptors-prevents vasconstriction

does not inhibit ace so NO COUGH-Less AEs

SWITCH TO THIS IF ACE MAKES COUGH

AES:increased K and altered kidney function
Term
Direct Vasodialtors
Definition
Hydralazinee
DECREASE in total PVR--> produces relaxation of vascualr smooth muscle

AEs: palpittaions, tachy, flushing, nasl congestion
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