Term
| Differentiate between reversible and irreversible cell injury |
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Definition
reversible: if the stress is removed in time or if the cell is able to w/stand assault, structural and fxnal integrity is restored
irreversible: severe stress beyond point of no return; may result in death |
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Term
| List 4 ultrastructural changes of intracellular organelles which may occur in the hydropic swelling of reversible injury |
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Definition
-endoplasmic reticulum become distended by fluid
-mitochondria swell
-plama membrane form cytoplasmic blebs
-nucleolus fibrillar nad granular components may segregate |
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Term
| 6 major celllular adaptive responses to chronic stres and def. |
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Definition
atropy
hypertropy
hyperplasia
metaplasia
dysplasia
intracellular storage |
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Term
| 3 common intracellular nutritional constituents that can accumulate abnormally during dysfxn of storage |
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Definition
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Term
| 3 most common causes of cellular death |
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Definition
viruses
ischemia
physical agents(radiation, extreme temp., toxic chemicals) |
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Term
| Describe stages during coagulative necrosis |
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Definition
-cell nucleus shows clumping of chromatic w/ redistribution along nuclear membrane
-nucleus becomes smaller(pyknosis) and may fragment thru out cytoplasm (karyorrhexis) or pyknotic nucleus may be extruded from cell. Nucleus may show progressive lossof chromatic staining (karyolysis) |
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Term
| Conditions under which liquefactive necrosis occurs |
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Definition
| PMNs are acute inflammation cells which congregate in response to a bacterial infection; they contain hydrolases which are capable of completely digesting dead cells, often forming an abscess. dissolution of tissue |
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Term
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Definition
| affects adipose tissue aand commonly results from pancreatitis or trauma. digestive enymes foundin the pancreatic duct and sam. intestine are released from injured pancreatic cells na ducts into the extracellular space. digest pancreas and surrounding tissue including adipose cells |
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