Term
What is the clinical manifestation of Vitiligo? What clinical associations are there to Vitiligo? Who is the poster boy for Vitiligo?
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Definition
Depigmented macules on Face, Hands and Axilla. Serum B12/folate deficiency, Addison's, Autoimmune thyroiditis, T-lymphocyte disorder. Michael Jackson.
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Term
What is the clinical presentation of Melasma? What is Melasma related to?
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Definition
Facial hyperpigmentation. Pregnancy "the mask of pregnancy" and oral contraceptives.
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Term
What is the medical term for freckles?
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Definition
Ephelides-tiny flat hyperpigmented macules. This is the most common pigmanted lesion. Fades over winter Darkens over summer
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Term
What is the clinical presentation of Lentigines? What is the histology?
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Definition
Flat hyperpigmented macules from sun exposure later in life. "Liver spots" or "Age spots" Thinned epidermis with elongated hyperpigmented (surrounded by melanocytes) clubshaped rete. Dermal solar elastosis will have a blue shade to the epidermis.
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Term
What are the ABCDs for assesing Nevi? What are the 3 basic types of Nevi?
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Definition
Asymmetry, Border, Color, Depth Junctional, Intradermal, Compound
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Term
What is the Clinical presentation of Congenital nevus? What is the clinical significance of Congenital nevus?
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Definition
Deep dermal/ subcutaneous growth. They have increaed melanoma risk.
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Term
What is the clinical presentation of Blue nevus? What is the histology? What is the clinical significance?
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Definition
A black and blue nodule often associated with fibrosis. Heavily pigmented nevus cells. Often confused with melanoma.
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