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Definition
Pathological condition of a part, organ, or system resulting from various causes such as infection genetic defect and environmental stress. characterized by an identifiable group of signs or symptoms |
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Abnormal vs. Normal Process |
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Definition
represent different points on same spectrum. Seeds of disease often lie within adaptive mechanism of body itself. Double edged sword. |
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Definition
a single measurement, observation, or lab result that indicates abnormality. must always be judged in the context of the entire situation of the individual |
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Definition
average values for height, weight, and BP. derived from observations of many individuals. |
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study of cause or origins. this is the branch of medicine that deals with the causes or origins of disease. |
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4 types of Cellular injury |
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Definition
oxygen decrease, physical (gun), living agent (bac. or vir), & chemical (CO) |
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How cells under attack adapt |
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Definition
Edema happens first. Water and fat (LHK) retention happens. Interferons released. |
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Most common forms of cellular degenerative change |
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Definition
Swelling with water in the cytoplasm (save HLK. Sometimes injuries will become malignant. |
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Degenerative change. process of phagocytizing a portion of protoplasm by vacuole within the cell. Liver spots are a good example. |
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Relationship between cellular death and acute inflammatory disase |
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Definition
When cells die they release an enzyme that starts the cleaning up process. this adjunct tissue response is called inflammation. |
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Definition
Premature death of cells and living tissue from irreversible damage |
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Definition
Tissue still retains architectural shape (toe of a diabetic) |
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Definition
Tissue liquefies and is no longer there (brain tissue post stroke) |
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Definition
Cavity forming. Tb causes this in the lungs. |
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Definition
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Definition
Calcium deposits in places where it should be. Lungs and arteries & sometimes particular disease (pigeons) |
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Definition
Stiffening of muscles post somatic death |
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Definition
Cooling of body post somatic death. (Checked in liver) |
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Definition
Pooling of blood post death. Gravity driven |
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Definition
Come from the outside. Examples are bacteria, trauma, & environmental chemicals. |
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Come from the inside. Age, gender & genetics |
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Have identified a specific gene that causes problem (ex. Downs Syndrome) |
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Definition
Problems evident at birth. Not always genetic (Fetal Alcohol) |
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Definition
Affects members of same family without necessarily being inherited. Obesity may be linked to eating MCD everyday. |
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