Term
| Norepinephrine and epinephrine are found in: |
|
Definition
| Postganglionic sympathetic nerve ending |
|
|
Term
In the biosynthesis of catecholamines:
Tyrosine is converted to this molecule by tyrosine hydroxylase. |
|
Definition
|
|
Term
In the biosynthesis of catecholamines:
DOPA is converted to this molecule by DOPA decarboxylase. |
|
Definition
|
|
Term
In the biosynthesis of catecholamines:
Dopamine is converted to this molecule by Dopamine-B-hydroxylase. |
|
Definition
| Noradrenaline (Norepinephrine) |
|
|
Term
In the biosynthesis of cathecholamines:
Noradrenaline (NE) is converted to this molecule by Phenylethanolamine-N-methyltransferase. |
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Definition
|
|
Term
| These two drugs are given to patients with Parkinson's Disease. |
|
Definition
|
|
Term
| Carbidopa blocks this enzyme: |
|
Definition
|
|
Term
| Tyrosine hydroxylase is found in the: |
|
Definition
|
|
Term
| Tyrosine hydroxylase is selective for: |
|
Definition
|
|
Term
| If you have a drug that blocks the synthesis of tyrosine hydroxylase, you will: |
|
Definition
| Block the synthesis of DOPA (and dopamine, NE, and E) |
|
|
Term
| This drug is a strong inhibitor of tyrosine hydroxylase. It is sometimes used in treatment of HTN. |
|
Definition
| alpha-methyltyrosine (Metyrosine) |
|
|
Term
| DOPA decarboxylase is found in: |
|
Definition
|
|
Term
| Is DOPA decarboxylase specific or non-specific? |
|
Definition
|
|
Term
| This drug used to treat Parkinson's Disease inhibits DOPA decarboxylase. |
|
Definition
|
|
Term
| Dopamine-B-hydroxylase is found in the: |
|
Definition
|
|
Term
| Dopamine-B-hydroxylase is an indicator of: |
|
Definition
| Sympathetic nerve activity |
|
|
Term
| Phenylethanolamine-N-methyltransferase is located in the: |
|
Definition
|
|
Term
| Phenylethanolamine-N-methyltransferase catalyzes the: |
|
Definition
|
|
Term
| Epinephrine and NE are synthesized in the: |
|
Definition
|
|
Term
|
Definition
| Inhibitor of the vesicular catecholamine pump |
|
|
Term
| In the sympathetic nervous system, this terminates the action of released NE: |
|
Definition
| Reuptake of the neurotransmitter |
|
|
Term
| Circulating EPI and NE are degraded by: |
|
Definition
|
|
Term
| Cocaine, tricyclic antidepressants, phenoxybenzamine, and amphetamine are examples of: |
|
Definition
|
|
Term
| Steroid hormones and phenoxybenzamine are examples of: |
|
Definition
|
|
Term
| Reserpine is an example of: |
|
Definition
| Vesicular transporter inhibitor |
|
|
Term
|
Definition
| In the outer membrane of mitochondria |
|
|
Term
|
Definition
|
|
Term
| This molecule found in wine, sausage, and cheese causes adverse effects in MAOIs: |
|
Definition
|
|
Term
| In the presence of MAOIs, this is taken up causing a massive release of NE. |
|
Definition
|
|
Term
| Consuming wine, cheese, or sausage while taking an MAOI could cause: |
|
Definition
| Hypertensive crisis due to massive release of NE |
|
|
Term
| COMT inhibitors are used to treat: |
|
Definition
|
|
Term
| Tolcapone and entacapone are: |
|
Definition
| COMT inhibitors used to treat Parkinson's Disease |
|
|
Term
| Activation of these receptors decrease NE release: |
|
Definition
|
|
Term
| Alpha and beta receptors are this kind of receptor |
|
Definition
|
|
Term
| Alpha-1 and alpha-2 receptors exist: |
|
Definition
|
|
Term
| Activation of alpha-1 receptors causes this in blood vessels: |
|
Definition
|
|
Term
| Alpha-2 receptors are located both: |
|
Definition
| Postsynaptically and presynaptically |
|
|
Term
|
Definition
| A selective alpha-1 agonist |
|
|
Term
|
Definition
| Selective alpha-2 agonist |
|
|
Term
|
Definition
| Selective alpha-1 antagonist |
|
|
Term
|
Definition
| Selective alpha-2 antagonist |
|
|
Term
| Alpha-1 receptors have this physiological effect: |
|
Definition
| Smooth muscle contraction |
|
|
Term
| Alpha-2 receptors cause this physiological effect: |
|
Definition
| Inhibition of transmitter release |
|
|
Term
| Alpha-1 receptors act through this GPCR: |
|
Definition
|
|
Term
| Alpha-2 receptors act through this GPCR: |
|
Definition
|
|
Term
| Beta-1 receptors are found primarily in: |
|
Definition
|
|
Term
| Beta-2 receptors are found primarily in: |
|
Definition
| Bronchial smooth muscle tissue |
|
|
Term
| Beta-3 receptors are found primarily in: |
|
Definition
|
|
Term
| Activation of beta-1 receptors causes these effects on the heart: |
|
Definition
| Increase contractile force; increase heart rate |
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|
