Shared Flashcard Set

Details

Pharm 1
alpha & beta blockers
21
Health Care
Professional
01/26/2009

Additional Health Care Flashcards

 


 

Cards

Term
Alpha 2 receptors
Definition

stimulated by catecholamines engage negative feedback, stopping further release of norepinepherine.

Term
Alpha 1 receptors
Definition
Adrenergic (sympathetic) stimulation with catecholamines causes vasoconstriction.
Term
Beta 1 receptors
Definition

Adrenergic (sympathetic) stimulation causes increase in heart rate.

Term
Beta 2 receptors
Definition
Adrenergic (sympathetic) stimulation causes bronchodilation, uterus relaxation, and vasodilation,peripheral arterial blood vessels to dilate
Term
Dopaminergic receptors
Definition

adrenergic (sympathetic) stimulation increases urine output due to better renal perfusion and improves symptoms r/t Parkinsons.

Term
Adrenergic/Sympathomimetic Agent Side Effects
Definition

Palpitations

Tachycardia

 Skin Flushing

 Dizziness

Tremors

 

Term

Adrenergic Agent 

albuterol

Proventil

Definition

Dose: Aerosol 90mcg per puff. Tablets 2, 4 mg. Syrup 2mg/5mL. ER Tablets4, 8 mg.

Adrenergic Recptr: Beta-2

Action: Bronchodilator

Use: Asthma, Emphysema

Term

Adrenergic Agent 

dopamine

Inotropin

Definition

Dose: IV: 40, 80, 160mg/mL in 5, 10, 20mL ampule

Adrenergic Recptr: Alpha, Beta-1, Dopaminergic

Action: Vasopressor(stimulates contraction of smooth muscle in arteries)

Use: Shock, hypotension, inotropic agent

Term

Adrenergic Agent 

dobutamine

Dobutrex

Definition

Dose: IV 250mg/20mL vials

Adrenergic Recptr: Beta-1

Action: Cardiac Stimulant

Use: Inotropic (increases force of muscles contract.)

Term

Adrenergic Agent 

epinepherine

Adrenaline

 

Definition

Dose: IV 1:1000 in 1mL ampules, 1:10,000 in 10mL prefilled syringes

Adrenergic Recptr: Alpha, Beta

Action: Allergic reactions, Vasoconstrictor, Bronchodilator, Cardiac Stimulant

Use: Anaphylaxis (allergic reaction), Cardiac Arrest, Topical Vasoconstrictor

Term

Adrenergic Agent

norepinephrine

Levophed

Definition

Dose: IV 1mg/mL in 4 mL ampules

Adrenergic Recptr: Alpha-1

Action: Vasoconstrictor

Use: Shock, Hypotension

Term

Beta-Adrenergic Blocker

atenolol

Tenormin

Definition

Available: Tablets:25, 50, 100mg Inj:0.5mg/mL in 10ml ampules

Use: Hypertension, Angina Pectoris, MI

Dose Range: Initial 50mg daily, maint. up to 200mg daily

Term

Beta-Andrenergic Blocker

metoprolol

Lopressor

Definition

Available:Tablets:50, 100mg ER Tabs:25,50,100,200mg Inj:1mg/mL in 5mL ampules

Use:Hypertension, MI, Angina Pectoris, heart fail.

Dosage Range: PO Initial 100mg daily. Maint. 100, 450mg daily.

Term

Beta-Adrenergic Blocker

nadolol

Corgard

Definition

Available: Tablets: 20,40,80,120,160mg

Use: Angina Pectoris, Hypertension

Dosage Range: PO Intial 40mg daily. Maint.80-320mg daily. Max 640mg daily.

Term

Beta-Adrenergic Blocker

propranolol

Inderal

Definition

Available: Tablets:10,20,40,60,80mg. Solution4,8,80mg/mL. Sustained release capsules 60,80,120,160mg. IV 1mg/mL in 1mL ampules

Use:Hypertension,Angina Pectoris, MI, Dysrythmias,Migraine,Tremor,Hypertrophic subaortic stenosis.

Dosage Range:PO Initial 40mg bid. Maint. 120-640mg daily. IV 1-3mg under close

Term

Beta-Andrenergic Blocker

sotalol

Betapace

Definition

Available: Tablets:80,120,160,240mg

Use: Dysrythmias

Dosage Range: PO Initial 80mg bid. Maint. up to 320mg daily

Term
Beta Blocker Side Effects
Definition

Bradycardia

Peripheral Vasoconstriction(purple mottled skin)

Bronchospasm(wheezing)

Heart failure

Term
Beta and Alpha Combo Blocker Side Effects
Definition

Ortho HTN

Dizziness

Nausea

Bradycardia

Dry Mouth

Impotence

Bronchospasm,wheezing

Term

Beta-Adrenergic Blocker

carvedilol

Coreg

Definition

Uses: Hypertension, MI, Heart Failure

 

Alpha and Beta combo blocker

Term

Beta Blockers Action

Definition
Reduce heart rate, cardiac output, and blood pressure
Term
Beta Blockers Contra's and HTN Stages
Definition

Stages 1 and 2 for intitial therapy

Contraindicated for pts with asthma, type 1 DM, heart failure caused by systolic dysfunction and PVD

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