Term
|
Definition
for arterial thrombosis
acute: glycoprotein 2b/3a inhibitor, abciximab, eptifibatide.
chronic: ASA, clopidogrel
thrombolytic
anti-fibrinolytic agent |
|
|
Term
|
Definition
glycoprotein 2b/3a inhibitor
sterically interferes
bound-antibody persist for 1-2 days. |
|
|
Term
|
Definition
glycoprotein 2b/3a inhibitor
directly competes |
|
|
Term
|
Definition
irreversible inhibitor of COX anti-platelet drug
chronic inhibition on platelet TXA2
pt. w/ CAD risk for MI
pt. w/ ccarotid artery / cerebral artery atherosclerosis for stroke/ITA
pt. w/ damaged endothelium: arterial prosthesis, valvular heard disease |
|
|
Term
|
Definition
ADP-dependent anti-platelet
chronic inhibition,
stronger anti-platelet
pt. w/ ACS
pt. w/ peripheral vascular disease
pt. w/ PCI
|
|
|
Term
|
Definition
| thrombolytic agent bind to fibrin, activate plasminogen |
|
|
Term
streptokinase
antistreplase |
|
Definition
thrombolytic agent
with previous strep infection: loading dose to saturate Ab, then IV.
antistreplase: 1:1 complex of streptokinase and modified plasminogen. act like tPA. |
|
|
Term
|
Definition
thrombolytic agent
lyse cclot in urinary tract.
by renal epi. |
|
|
Term
|
Definition
anti-fibrinolytic
inhibit plasminogen binding to fibrin |
|
|
Term
|
Definition
heparin
warfarin
rivaroxaban |
|
|
Term
|
Definition
anti-thrombin sulfated proteoglycan by mast cell
acute
prophylactics.
clear fast by macrophage, liver
induce immune thrombocytopenia |
|
|
Term
|
Definition
| competitive vit. K reductase antagonist |
|
|
Term
|
Definition
factor 10 antagonist
deep vein thrombosis
thrombophlebitis |
|
|
Term
| glycoprotein 2b/3a inhibitor |
|
Definition
acute anti-platelet
block platelet membrane fibrinogen receptor
thrombosis + PCA
pt. with ACS to prevent MI
abciximab
eptifibatide |
|
|
