Term
|
Definition
Acute Angina
Stable Angina
Variant Angina
Prophylaxis: oral, ointment, or patch |
|
|
Term
|
Definition
Smooth muscle dilator Veins>Arteries
Dec. ED = Dec O2 demand
NO donor |
|
|
Term
| Examples of Nitrates and how administered |
|
Definition
Nitroglycerin (Sublingual)
Isosorbide mono/dinitrate (Oral) |
|
|
Term
|
Definition
Reflex Tachycardia = INc. O2 demand
Tolerance-need free period at night w/ Isosorbide
Headache, weakness, hypotension |
|
|
Term
| How do Beta-blockers work |
|
Definition
Block Sympathetic effects on heart
Dec. HR and contractility = Dec. O2 demand |
|
|
Term
|
Definition
Propranolol- nonselective
Metroprolol- B1 selective |
|
|
Term
|
Definition
Prophylaxis
Reduced mortality Post-MI
Stable Angina |
|
|
Term
| Adverse Effects of Beta-blockers |
|
Definition
Rebound, fatigue, cardiac suppression
NOT w/ variant angina
Caution: DM, Asthma, HF,PVD |
|
|
Term
| Examples of Calcium Channel blockers |
|
Definition
Verapamil - most cardiac muscle
Diltiazem
Nifedipine - smooth muscle |
|
|
Term
| How Calcium Channel blockers work |
|
Definition
All 3 cause vasodilation =
dec. coronary vascular resistance =
inc. coronary blood flow =
inc. O2 supply |
|
|
Term
| How does Nifedipine work and contraindications |
|
Definition
Arterial dilation = Dec. O2 Demand
Dec. HR
Dec. Contractility can = Reflex |
|
|
Term
| How to Verapamil and Diltiazem work |
|
Definition
Dilation
No reflex b/c directly effect heart and dec. contractility
Inc. O2 demand |
|
|
Term
| Calcium channel blockers are 1st choice for |
|
Definition
|
|
Term
| Verapamil and Diltiazem are 2nd choice for what |
|
Definition
|
|
Term
| Side effects of all calcium blockers |
|
Definition
|
|
Term
| Side effects Verapamil and Diltiazem |
|
Definition
| Dec. contractility, bradycardia, AV slowing |
|
|
Term
| Nitrates and Beta-blockers |
|
Definition
Dec. O2 demand,
Beta-Block stops nitrate's reflex Tachycardia |
|
|
Term
| Beta-blocker and Ca2+ channel blocker |
|
Definition
ONLY Nifedipine
Beta-block blunts reflex tachycardia
(Verap/Dilt riask too much cardiac suppression) |
|
|
