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Pharm Quiz 4
QSIA
51
Medical
Not Applicable
10/21/2010

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Term
Petechial hemorrhages within the mamillary bodies imply
Definition
chronic alcoholism and thiamine deficiency
Term
perifollicular rash, gingival hemorrhages, rachitic rosary, hemarthrosis, anemia, and impaired wound healing indicate a deficiency in vitamin___
Definition
C
Term
The fatty liver of Kwashiorkor is most likely the result of:
Definition
Decreased synthesis of carrier apoproteins
Term
A 40 y/o schizo male drank lots of Geritol (containing vitamins and iron). His liver would likely show:
Definition
Hemochromatosis
Term
Which is not a free radical acceptor of:
ceruloplasmin
glutathione
melatonin
transferrin
vitamim A
Definition
vitamin A
Term
What do you call a bleeding def due to scurvy, lack of platelets, or lack of coagulation factors?
Definition
Hemorrhagic diathesis
Term
An alcholic with double vision who can't follow a moving finger with his eyes lacks which vitamin?
Definition
B1
Term
Wernicke's syndrome is associated with each of the following except:
ataxia
confusion
hemorrhage in mamillary bodies
nystagmus
vitamin B12 def
Definition
vitamin B12 def
Term
Each of the following is associated with cobalamin (B12) def except:
atrophic gastritis
folate antagonists
pernicious anemia
spinal cord demyelination
strict vegetarianism
Definition
folate antagonists
Term
Liver findings in Kwashiorkor do NOT include:
Definition
cirrhosis
Term
Vitamin D
Definition
increases intestinal Ca absorption
Term
On autopsy: pleuritis, thickening of the glomerular capillary walls, collagen rings around splenic arterioles, excrescences on mitral valve. What's found in the blood?
Definition
ANAs
Term
Tissue necrosis in immune complex vasculitis is accomplished by:
Definition
proteolytic digestion by leukocytes, followed by complement activation
Term
What mediates tissue injury in SLE?
Definition
Activation of complement by immune complexes
Term
What type of hypersensitivity reaction is contact dermatitis?
Definition
type IV
Term
The most frequent immunological conditions are:
Definition
atopic allergies
Term
Pathogenetically, a hyperacute transplant reaction resembles:
Definition
arthus immune response
Term
What organ is least frequently involved in scleroderma?
Definition
liver
Term
A patient presents with elevated IgM and IgG, general lymphadenopathy, and heavy proteinuria. The most likely diagnosis is:
Definition
AIDS
Term
19 y/o pregnant woman with dyspnea and pain during pregnancy. High probability of pulmonary thromboembolism. What's likely to be found in her blood?
Definition
anti-phospholipid antibody
Term
What do macrophages produce that kills pathogens, but causes hypotension?
Definition
NO
Term
What secretes substances that perforate membranes on infected cells?
Definition
NK cells
Term
SLE does NOT include:
Definition
the Hep B antigen
Term
Mixed CT diseases do NOT include:
Definition
renal failure
Term
Sjogren's syndrome does NOT include:
Definition
hypergammaglobulinemia
Term
Which pair is not correct:
SLE--smith AG
Sjogren's--anti-SS-B antibody
mixed CT disease--anti-nRNP AB
polyarteritis nodosa--dsDNA AB
sclerosis--anti SCL-70 AB
Definition
polyarteritis nodosa--anti dsDNA AB
Term
Proliferative glomerulonephritis is associated with:
Definition
Goodpasture's
Term
CYP 450
Definition
may activate xenobiotics to carcinogens
Term
The temporary cavity of a high velocity bullet
Definition
is produced by crushing and tearing of the tissue
Term
Acute cyanide intoxication is an example of:
Definition
histotoxic anoxia
Term
What is not part of the mechanims of drowing?
Definition
hyperthermia
Term
Amyloidosis complicating chronic inflammatory disease is least likely to occur in the:
Definition
lymph nodes
Term
Amyloid in multiple myeloma is usually found in:
Definition
tissues of mesenchymal origin
Term
What is true about amyloidosis?
Definition
The AA type is found in reactive systemic amyloidosis
Term
What does Goodpasture's do to the heart?
Definition
myocardial hypertrophy
Term
Does Grave's have an increased risk for lymphoid malignancy?
Definition
NO
Term
Bronchial asthma is characterized by
Definition
atrophy of bronchial glands
Term
What's the prob with pregnancy and SLE?
Definition
elevated estrogen accelerates the disease
Term
What is not typical of scleroderma?
Definition
Libman-Sacks endocarditis
Term
Serum sickness is NOT characterized by:
Definition
hypercomplimentemia
Term
What can be given to prevent hemolytic disease of the newborn?
Definition
ABs to Rh + blood cells
Term
What mediates delayed graph reaction?
Definition
cell mediated immune reaction
Term
Arthus or immune complex reactions typically produce:
Definition
vasculitis with thrombosis and fibroid necrosis
Term
The Coomb's test detects
Definition
immune hemolytic anemia
Term
What mediates delayed rejection reactions?
Definition
lymphocytes
Term
What causes tissue damage in autoimmune diseases?
Definition
Type III hypersensitivity
Term
Alcoholism is NOT implicated in
Definition
interstitial nephritis
Term
Carbon tetrachloride injures
Definition
renal cells and hepatocytes
Term
Hyperkeratosis and squamous metaplasia is associated with def vitamin___
Definition
A
Term
Night blindness is associated with def vitamin:
Definition
A
Term
The abnormal process in scurvy is:
Definition
failure of osteoid formation
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