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-injectables -ophthalmics -inhalations -irrigation fluids -dialysis -implants |
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why parenteral administration? |
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Definition
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Term
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-drug injection -drug for injection -drug injectable emulsions -drug injectable suspension -drug for injectable suspension |
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parenterals unique characteristics |
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Definition
-sterile -free of pyrogens -free of foreign particulates -isotonic -compatible with IV diluents and delivery systems and other drugs products co administered -costly -requires special skills for administration |
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Definition
-fever producing substances |
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Definition
-destroy/remove all organisms |
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-under the skin -45 degree angle -past dermis |
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Definition
-immediate drug action -beneficial for life saving -deadly for mistakes -fluid, electrolyte, nutrition -dosage forms-solutions, lipid emulsions |
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Definition
-Chris Wren injected solutions and drugs into dogs and watched effects -given to humans in 1662 -mid 19th century-creation of hypodermic needle -late 19th century-solutions of NaCl and dextrose |
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Definition
-peripheral veins-antecubital area, dorsal forearm area -central veins-large veins in thoracic cavity (ex. subclavian vein) -for irritating drugs or hypertonic solutions -for patients requiring LT IV therapy -when a peripheral line cannot be maintained |
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IV route administration routes |
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Definition
-continuous infusion -intermittent infusion |
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Term
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Definition
-slow, large volume -for fluid, electrolyte, and nutrient replacement -for maintaining a therapeutics drug level (mostly drugs with a narrow therapeutic index) -by gravity or pumps -flow rates (ml/min, ml/hr,drops/min) -need to be carefully calculated and monitored |
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Definition
-for medications needed only at certain times -administration thru mini bags, additive chambers, bolus injection (make sure compatible) |
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IV route electronic delivery systems |
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Definition
-improved accuracy. safety, patient convenience -used for intermittent and continuous infusion -ex. patient controlled analgesia (PCA) -compact design -predictable and consistent drug plasma levels -dose on demand -control the pain without overuse of drugs |
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-embolism due to thrombi (blood clots), particulates, air (small amt is ok) -phlebitis-inflamation of vein -hypothermia (1g amt of fluid?) -infection |
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Definition
-slower onset than IV -duration can be longer? -dosage forms-aqueous and oleaginous solutions -suspensions (slower onset, longer duration) and emulsions |
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-deep into skeletal muscles -adults-gluteus maximus (<5ml) and deltoid (<2ml) -infants-upper arm or thigh (<2ml) |
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Definition
-beneath skin, into loose interstitial tissue -upper arm, thigh, lower abdomen (<2ml) -used for insulin -thin and short needles |
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Definition
-into skin, just beneath epidermis -anterior forearm (~0.1ml) -used for skin test and certain vaccines -thin and short needles |
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