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Details

Pharmaceutics
Preservatives
9
Medical
Graduate
11/16/2010

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Cards

Term
Alcohols and Glycols Indlude:
Definition
Ethyl Alcohol (5-10%), Propylene Glycol(5-10%), Glycerin (50%)

Benzyl Alcohol (1-2%)
Term
Ethyl Alcohol,propylene glycol, and glycerin functions to:
Definition
Aid in the solubilization of poorly soluble drugs
Term
Benzyl Alcohol Functions to:
Definition
Have a local anesthetic activity. Commonly used in topical and parenteral products
Term
Organic Acids include:
Definition
Benzoic Acid/Sodium Benzoate (Effective only at pH less than 5) and Sorbic Acid/Potassium Sorbate (Slightly more effective and less toxic)
Term
Parabens include:
Definition
Methylparaben, propylparaben. One of the most widely used. Effective at low pH and has limited water solubility
Term
QUAT Ammonium Compounds include:
Definition
Benzalkonium Chloride, benzethonium chloride, cetylpuridinium chloride
Term
Imidazolidinyl Ureas are:
Definition
effective over a wide pH range, safe, and compatible with most agents.
Term
Benzalkonium Chloride, benzethonium chloride, cetylpuridinium chloride (The QUATs) are used in function to:
Definition
As cationic surfactants, emulsifying or suspending agents.
Term
Alcohols and Glycols, Oranic Acids, Prabens, QUATs, and Imidazonolidinyl Ureas are all:
Definition
Preservatives
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