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Pharmacology Quiz - Karch - Ch. 50-59
Pharmacology Quiz - Karch - Ch. 50-59
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Pharmacology
Undergraduate 2
10/11/2009

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Term
The funtional unit of the kidney is called what?
Definition
The nephron (p828)
Term
The kidney activates what fat soluble vitamin to help regulate calcium levels in the body?
Definition
Vitamin D (p828)
Term
The kidneys regulate blood pressure through what system?
Definition
The renin-angiotensin system (p831)
Term
Kidneys regulate red blood cell production via production and secretion of what substance?
Definition
Erythropoietin (p832)
Term
The nephrons funtion by using these three basic processes.
Definition
Filtration, secretion and reabsorption (p829)
Term
A clinical sign of renal damage is this in the urine.
Definition
Protein or blood cells (p830)
Term
This adrenal hormone is released into circulation in response to high potassium levels, sympathetic stimulation or angiotensin III.
Definition
Aldosterone (p830)
Term
As a result of aldosterone stimulation, this cation is reabsorbed into the system and potassium is lost in the filtrate of the kidney
Definition
Sodium (p830)
Term
This hormone causes a decrease in sodium reabsorption from the distal tubules with a resultant dilute urine or increased volume.
Definition
Natriuretic hormone (p830)
Term
This hormone is released from the posterior pituitary gland in response to falling blood volume, sympathetic stimulation or rising sodium levels in the body.
Definition
Antidiuretic hormone (ADH) (p830)
Term
Diuretics are of greatest clinical significance because of their ability to secrete this.
Definition
Sodium (p836)
Term
These drugs are indicated for the treatment of edema, acute pulmonary edema, liver and kidney disease, and for the treatement of hypertension.
Definition
Diuretics (p836)
Term
This is the most frequently used thiazide diuretic, often used on combination with other drugs to treat hypertension.
Definition
Hydrochlorothiazide (p837)
Term
Diuretcs increase excretion of this cation, and therefore water from the kidneys
Definition
Sodium (p837)
Term
Thiazides work in this major site of action of the nephron.
Definition
Distal convoluted tubule (p838)
Term
Loop diuretics work in this major site of action of the nephron.
Definition
Loop of Henle (p838)
Term
Carbonic anhydrase inhibitors work in this major site of action of the nephron.
Definition
Proximal tubule (p838)
Term
Potassium-sparing diuretics work in this major site of action of the nephron.
Definition
Distal tubule and collecting duct (p838)
Term
Osmotic diuretics work in this major site of action of the nephron.
Definition
Glomerulus, tubule (p838)
Term
Thiazides are considered (potent or mild) diuretics compared to loop diuretics.
Definition
Mild (p383) (Loop diuretics are more potent than thiazides)
Term
When thiazide diuretics are used, the urine will be slightly (acidized or alkalinized, choose one) because they block the reabsorption of bicarbonate.
Definition
Alkalinized (p840)
Term
These diuretics are also known as high-ceiling diuretics because they cause a greater degree of diuresis than other diuretecs to.
Definition
Loop diuretics (p840)
Term
As bicarbonate and calcium are lost in the urine, this electrolyte imbalance can occur.
Definition
Alkalosis (p841)
Term
This commonly prescribed loop diuretic (whose trade name sounds like the name of cafe in the West Hollywood neighborhood) can produce a fluid loss of up to 20 lb/day.
Definition
Furosemide (Lasix) (p841 / Basix Cafe http://www.basixcafe.com/)
Term
If hypokalemia develops in a patient taking a thiazide or loop diuretic, this class of diuretic is often added to the prescription.
Definition
Potassium-Sparing Diuretics (p845)
Term
This type of diuretic acts to pull large amounts of fluid into the urine by osmotic pull of the larger sugar molecule and are diuretics of choice in case of increased cranial pressure due to shock, drug OD or trauma.
Definition
Osmotic diuretics (p846,7)
Term
Urinary tract anti-infctives act to destroy bacteria either through direct antibiotic effect or through what of the urine?
Definition
Acidification (p854)
Term
What new UTI drug comes in a one-dose-only form?
Definition
Fosfomycin (Monurol) (p853,4)
Term
This urinary tract analgesic should not be taken for more than two days because of its risk for renal or hepatic toxicity.
Definition
Phenazopyridine (p860)
Term
Cystitis is the infalammation of what?
Definition
The bladder
Term
These two BPH drugs are rated Pregnancy Category X and have no indications for women because of their androgen effects. Because of this, patients currently using either drug cannot donate blood.
Definition
finasteride and dutasteride (p863)
Term
The exchange of gases at the alveolar level is called what?
Definition
Ventilation (p871)
Term
The collapse of a once-expanded lung is called what?
Definition
Atelectasis (p873)
Term
Pneumonia comes in these three varieties:
Definition
Bacterial, viral, or aspiration (p872)
Term
COPD is caused by these two relatd disorders:
Definition
Emphysema and chronic bronchitis (p873)
Term
This OTC antitussive blocks the cough reflex.
Definition
Dextromethorphan (p879)
Term
This adverse effect associated with topical decongestants occurs when nasal passages become congested as the drug wears off.
Definition
Rebound congestion (p881)
Term
This class of nasal decongestants has a local anti-inflammatory action but may sting, burn or cause a headache.
Definition
Topical steroids (p885)
Term
This drug is the only available expectorant, should not be used for more than 1 week, and acts to thin secretions to produce a more productive cough.
Definition
Guaifenesin (p892)
Term
The mucolytic Dornase Alpha is prescribed mostly for what ailment?
Definition
Cystic fibrosis (p894)
Term
This type of respiration, marked by a period of apnea followed by hyperventilation, may indicate a grave prognosis in adults but may be normal in children.
Definition
Cheyne-Stokes respiration (p901)
Term
A drug from this class is the drug of choice in most acute asthma cases.
Definition
Inhaled beta-agonists (p901)
Term
The alveolar obstruction in Respiratory Distress Syndrome (RDS) in the neonate is related to the lack of this.
Definition
Lipoprotein surfactant (p900)
Term
Because of this class of bronchodilator's relatively narrow safety margin and because drugs in it interact with many other drugs, they are no longer considered the first choice to treat respiratory disease.
Definition
Xanthines (p900)
Term
This drug found in cigarette smoke increases the metabolism of xanthines in the liver, therefore a prescribed xanthine's dose may have to be highter in smoking clients.
Definition
Nicotine (p902)
Term
This class of anti-asthmatic drug is oftern used concomitantly with corticosteroids.
Definition
Mast Cell Stabilizers (p918)
Term
This mast cell stabilizer in the form of eye drops should not be used with soft contacts - or the contacts should be removed first.
Definition
Cromolyn (p919)
Term
This stomach secretion stimulates the stomach muscles to contract, the parietal cells to release HCl and chief cells to release pepsin.
Definition
Gastrin (p927)
Term
Gastrin and the parasympathetic system stimulate these near the parietal cells, causing the cells to release HCl into the stomach.
Definition
Histamine-2 (H2) receptors (p927)
Term
In the small intestine, this substance neutralizes the acid bolus coming from the stomach.
Definition
Sodium Bicarbonate (p927)
Term
If fat is present in the stomach's bolus, when it moves to the small intestine, this substance is secreted from galbladder contraction.
Definition
Bile (p927)
Term
This process is used in the small intestine to expose a greater surface area of chyme to increase absorption.
Definition
Segmentation (p928)
Term
The large intestines secrete a large amount of this to facilitate movement of food through the GI tract.
Definition
Mucus (p928)
Term
The vomiting reflex is stimulated by two centers in this part of the brain which stimulate projectile vomiting.
Definition
The medulla (p929)
Term
Most nutrient absorpton occurs in this part of the GI tract.
Definition
The small intestine (p928)
Term
This class of GI drug blocks the release of HCl in response to gastrin.
Definition
Histamine-2 (H2) Antagonists (p935)
Term
This class of GI drugs neutralize acids at the chemical level.
Definition
Antacids (p935)
Term
This class of GI drugs act at specific secretory surface receptors to suppress the secretion of HCl in the lumen of the stomach.
Definition
Proton pump inhibitors (p935, 944)
Term
This class of GI drugs coat any injured area of the stomach (like ulcers) to prevent further injury from acid.
Definition
Antipeptic agents (p935)
Term
This class of GI drugs inhibit the secretion of gastrin and increase the secretion of protective mucous in the lining of the stomach.
Definition
Prostaglandins
Term
This H2 antagoinst is the drug of choice for patients with liver dysfuntion because it is eliminated by the kidneys.
Definition
Nizatidine (Axid)
Term
Administering an antacid frequently can cause this undesired effect.
Definition
Acid rebound (p941)
Term
This antipeptic agent should not be given with aluminum based antacids due to aluminum toxicity risks and should not be given with other antacids within 30 minutes.
Definition
Sucralfate (p946)
Term
This laxative is used to evacuate the bowel in cases of poison ingestion as well as being uses as an anthelmintic agent (i.e. as a wormer).
Definition
Castor oil (p957)
Term
These actions can eliminate the need for laxatives in many situations.
Definition
Eating a proper diet and getting enough exercise. (p967)
Term
True or False: Ipecac syrup is recommended for accidental home poisonings.
Definition
False (p970)
Term
5-HT3 Receptor Blockers are what and prevent what?
Definition
Antiemetic agents, prevent nausea and vomiting in chemotherapy patients (p973)
Term
Substance P/Neurokinin 1 Receptor Antagonists do what?
Definition
Treat nausea and vomiting related to chemotherapy. (p975)
Term
Increased sensisitivity to the sun or this, is a common adverse reaction with many antiemetics.
Definition
Photosensitivity (p977)
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