Term
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Definition
| tremor, numbness, tingling, Parkinsonian symptoms, orthostatic hypotension, anticholinergic effects, cardiac srrhythmias, & suicidal actions |
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Term
| Nursing interventions for TCA |
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Definition
don't use with MAOIs
Sympathomimetics increases effects of anticholinergic effects
Avoid OTC antihistamines
Prototype: imipramine (Tofranil) |
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Term
|
Definition
Prototype: sertraline (Zoloft)
Action: inhibits reuptake of serotonin |
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Term
|
Definition
| Use: depression, anxiety, OCD, & panic disorder |
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Term
|
Definition
| Contradictions: antabuse should be avoided; no MAOIs; use precaution with St. John Wart |
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Term
|
Definition
| Adverse Effects: agitation, HA, dizziness, fatigue, sexual dysfunction, weight gain |
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Term
SSRI
Nursing interventions |
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Definition
May take weeks to get effect
Effect last 2-3 months after d/c
Give in AM or PM
Note eating disorder hx
Exercise & caloric restriction
Monitor labs for pro-bound drugs...ex:coumadin
May need increase of dilantin due to interactions |
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Term
|
Definition
Prototype: Phenelzine (Nardil)
Action: intensifies effects of norepinephrine in adrenergic synapes |
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Term
|
Definition
| depression not responsive to other drugs |
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Term
|
Definition
| constipation, dry mouth, orthostatic hypertension; severe hypertension with foods containing tyramine (avocados, bannanas, raisins, papaya products, canned figs, cheese, sour cream, yogurt, beer, wines, liver, pate, chocolate, ect.) |
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Term
MAOI
Contraindications & Nursing Implications |
|
Definition
C:cardiac disease, renal/hepatic impairment
NI:cardiac status, lab values, no OTC or herbal meds, avoid caffeine, observe for s/s of stroke or MI |
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Term
|
Definition
| it promotes release of norepinephrine |
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Term
Discuss the uses for antimanic agents:
Lithium carbonate (Eskalith)
Action & common S/E |
|
Definition
A:stabalizes the neuronal membrane, reduces release of norepinephrine
S/E:n/v, anorexia, abd cramps, excessive thirst & urination |
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Term
|
Definition
| Adverse effects:persistant vomiting; progressive wt gain, fatigue, nephrotoxicity |
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Term
|
Definition
check labs weekly
give with food or milk
desired effects in 5-7 days
full effect in 21 days
make sure VS are normal before giving |
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Term
|
Definition
phenothiazines
non phenothiazine
atypical anti psychotics |
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Term
Phenothiazines
Prototype & Use |
|
Definition
P: Chlorpromazine (Thorazine)
Use: schizophrenia, bipolar (manic state), depression, antiemetic
WORKS AS LONG AS THEY USE IT |
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Term
|
Definition
| Prevent dopamine & serotonin for occupying their receptor sites and block the excitement symptoms |
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Term
Phenothiazines
Adverse effects |
|
Definition
| acute dystonia, akathsia, anticholinergic effects (dry mouth, tachycardia, blurred vision), hypotension, neuroleptic malignant syndrome, parkinsonism, sedation, sexual dysfunction,tardive dyskinesia |
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Term
Phenothiazines
Nursing Interventions |
|
Definition
| increases effect with anticholinergics, ETOH & CNS depressants intensify depressant effect, most end in 'zine', careful monitoring of client condition, report extrapyramidal side effects to the MD |
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Term
Non phenothiazines
Prototype & action/use |
|
Definition
p:Haloperidol (Haldol)-not nice
a/u:chemically a butyrphenone; primary use is psychotic disorder-has less sedation than phenothiazine, but greater than EPS |
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Term
|
Definition
P:Clozapine (Clozaril)
A/U:Largely unknown-block several receptors sites; broader spectrum of action, fewer EPS symptoms
NI:weekly lab values |
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Term
|
Definition
new drug aripiprazole (abilify)
dopamine stabilizer with fewer EPS
Adverse effects:HA, N/V, fevers, constipation, anxiety |
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