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Pharmacology
Test #6
51
Other
Not Applicable
06/17/2004

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Cards

Term
What are the side effects of Sulfonlyureas? (3)
Definition
Hypoglycemia, cardiotoxicity and weight gain (10#+)
Term
What do sulfonlyureas help do and what is an contraindication?
Definition
Promote insulin release and allergy is a problem to sulfa
Term
What do meglitinides do and what is the prototype?
Definition
Stimulate pancreatic insulin release. Repaglinide is prototype
Term
What is the side effect of meglitinides and what do you not give sulfonlyureas with meglitinides?
Definition
Side effect: hypoglycemia. Don't give together because they have the same action.
Term
Insulin Glargine: How long does it last? When do you usually give it? Can it be mixed with other insulin?
Definition
Lasts 24+ hrs. $$$ given at bedtime as basal dose and CAN NOT be mixed
Term
Lispro insulin (Humalog) what's the onset and how long does it last?
Definition
very rapid onset and shorter duration than regular insulin and more $
Term
Insulin aspart: how quick and how long do it last?
Definition
Very fast and short but $$
Term
NPH Insulin: Can it be mixed? How long and how fast?
Definition
Cloudy, longer onset and action CAN be mixed with regular insulin
Term
Tell me about Lente and ultralente insulin compared with NPH. Can it be mixed with others?
Definition
less allergic than NPH but CAN NOT be mixed with others.
Term
What does Metformin do?
Definition
Decreases production of glucose by the liver used to prevent type 2 DM
Term
What are some side effects of Metformin? What really needs to be healthy to be Rx this?
Definition
SE: decreased appetite, N and diarrhea. NND healthy kidneys for excretion
Term
What does the drug Acarbose do?
Definition
Delays absorptoin of Carbs.
Term
What are some side effects of Acarbose and what organ does it affect mostly?
Definition
flatulence, cramps, diarrhea, bloating, loud bowel sounds (borborygmus) Long term use impact liver
Term
What are glucocortoids? and what are they used for?
Definition
they are stress hormones, carb, fat and protein metabolism. They are used for replacement therapy and for autoimmune therapy: allergy, Reumatoid arthi or SLE for example
Term
What are some side effects of glucocortoids?
Definition
adrenal insufficiency, osteoporosis, elevated blood sugar, risk of infections and slow healing
Term
Name some side effects of androgens.
Definition
Virilization (2ndary sex changes, premature bone closure, choleterol changes and edema
Term
Name some uses for androgens.
Definition
Replacement therapy, use in breast cancer, sex drive stimulant, muscle bulking agent and delay puberty
Term
What does estrogen do?
Definition
Maintains bone mass and lowers cholesterol
Term
Name some side effects of esterogen.
Definition
endometrial, overian and breast cancer, N
Term
What are some uses of estrogen.
Definition
Replacement therapy and tx of prostate cancer
Term
What does progestin cause and what are some side effects?
Definition
causes bleeding. SE: breast tenderness, spotting, amenorrhea
Term
Progestin is used for......
Definition
PMS tx, endometrosis, uterine bleeding
Term
What are the first and second generation antihistamines?
Definition
1st-diphenhydramine (Benadryl)
2nd- Fexofenadine (Allegra)
Term
Name some uses for antihistimes
Definition
allergy, motion sickness, insomnia, cold systoms
Term
Name some drug interactions for antihistimes.
Definition
alochol, 2nd yeast and some antibiotics result in dysrythmias
Term
Birth control may do what?
Definition
Raise blood sugar and BP, risk of multiple births when first discontinued.
Term
Name the two major drug groups for asthma.
Definition
Anti-inflammatory and bronchodilators
Term
What are the anti-inflammatory drugs for asthma?
Definition
Glucocortoids and Leukotriene modifiers
Term
What are the bronchodilators drugs for asthma?
Definition
Beta 2 Agonists, anticholingerics and Theophylline
Term
Uses of Beta 2 Agonists. What is the prototype?
Definition
Asthma, COPD, bronchodilation and stopping of uterine contractions////
Albuterol
Term
Name some asthma management techniques. (3)
Definition
1. Monitoring lung function: Flow meter 2. Stepped care 3. Avoid triggers 3. Hydration (thins mucous)
Term
Nasal decongestrants are usually what type of drugs?
Definition
Alpha 1 agonists
Term
Name the three types of cough meds and define each.
Definition
1. anti-tussive- cough suppresant
2. expectorant- Gets mucous up and out
3. mucolytics- breaks down mucous, make thinner
Term
What are some side effects of Albuterol?
Definition
CNS and CV stimulatin often tremors because they are beta 2 agonists
Term
Albuterol is used for what kind of situations?
Definition
For exercise PRN ans emerg. med.
Term
What are some uses of Cimetadine (Tagamet)?
Definition
ulcers, reflux, indigestion, and aspiration pneumonitis
Term
What are the side effects of Cimetadine?
Definition
Anti-andogenic properties (fat pad shifting, gynemastocia (boobs) and CNS effects (confusion, hallucinations, depression)
Term
What is so good about Ranitidine (Zantac)?
Definition
More potent, fewer side effects and drug interactions
Term
Omeprazole (Prilosec) is what kind of drug and what SE's does it have?
Definition
Proton pump inhibitor (PPI) SE: headache, diarrhea, N and V
Term
What do you have to beware when giving Sucralfate?
Definition
It will bind with other meds and minerals so you have to give it alone. Give with adequate H2O
Term
What is the side effect of Sucralfate?
Definition
Constipation
Term
What are the side effects of antacids (2)
Definition
Constipation and diarrhea
Term
What should you not do when you take an antacid?
Definition
Do not take it with other meds as impairs absorption
Term
What are these ingredients (Na, Mg, Ca) contraindicated for what kind of patients?
Definition
Na for heart and blood pressure///Mg for renal///Ca for kidney stones
Term
Define bulk formers? Can they be dosed to regulate consistency?
Definition
increase bulk and weight by water retention so gravity says downhill////Yes
Term
What type of laxative would you want to give to a heart patient or the elderly?
Definition
Bulk former so no strain.
Term
Define surfactants
Definition
Help stool to retain H2O
Term
Define stimulants. What is bad about them?
Definition
Stimulate muscle and H2O retention but cramps and fat vit. losses
Term
What type of laxative draw H2O into stool? What kind of problem does it have?
Definition
Osmotics. Problem: W/ electrolytes (K,Mg) hard on heart and kidney patients
Term
What cleanses bowel for X-ray but it doesn't give cramps or has electrolyte losses? How is it dosed?
Definition
Golytely///Drink 3L in 3 hrs ( 1C every 15 mins )
Term
What are three non drug helps for relieving constipation?
Definition
hydration, exercise, fiber
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