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Pharmacology
Drug cards
205
Other
Professional
11/19/2007

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Cards

Term
dilantin
Definition
phenytoin
Term
dilantin
Definition
antiarrhythmic agent
Term
management of generalized tonic-clonic, complex partial seizures
Definition
dilantin (phenytoin)
Term
vitamin C
Definition
ascorbic acid
Term

Vitamin B comlex

use

Definition
supplement for se in the wasting syndrome in chronic renal failure, uremia,impaired metabolic functions of the kidney, dialysis: labeled for OC as a dietary supplement
Term
vitamin c ascorbic acid
Definition
prevention and treatment of scurvy
Term

vitamin c ascorbic acid

Definition
necessary for collagen formation and tissue repair
Term
vitamin c ascorbic acid
Definition
involved in some oxidation-redution reactions as well as other metabolic pathways, such as synthesis of carnitine steroids and catecholamine and conversion of folic acid to folinic acid
Term
vitamin c ascobic acid
Definition
1%-10% renal: hyperoxaluria with large doses
Term
hyperoxaluria
Definition
excessive level of oxalic acid or oxalates inthe urine
Term
viatin c drug interactions
Definition
no significant effects or complications
Term
vitamin c
Definition
is a sugar acid that readily undergoes oxidation to form dehydroascorbic acid
Term
sources of ascorbic acid
Definition
citrus fruits, green peppers, tomatoes,strawberries,broccoli, raw cabbage, baked potatoes and papaya
Term
flumazenil: drug class
Definition
benzodiazepine
Term
flumazenil; indication/use
Definition
benzodiazepine antagonist: reverses effects of benzodiazepine used in conscious sedation and general anesthesia
Term
flumazenil: action
Definition
competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex. Does not antagonize the CNS effect of drugs affecting GABA-ergic neurons by means other than the benzodiazepine receptor: patients who are showing signs of serious cyclic-antidepressant over dosage.
Term
vitamin B complex side effects
Definition
CNS somnoence, itching, bloating constipation,diarrhea,flatulence,nausea,vomiting, thrombosis,paresthesia and allergic reactions
Term
vitamin B complex deficiency
Definition
angular cheiosis and glossitis
Term
vitamin b deficiency
Definition
beriberi
Term

vitamin B2 deficiency (riboflavin)

Definition
angular cheilosis
Term
vitamin B3 Niacin deficiency
Definition
pellegra, glossitis, dimensia
Term
vitamin K
Definition
helps synthesis clotting factor II,VII,IX,X
Term
warfarin affects
Definition
vitamin K
Term
vitamin K use
Definition
prevention & treatment of hypoprothrombinemia ( caused by malabsorption or inability to synthesize ?) .caused boumarin derivative induced or other drug induced deficiency, hmorrhagic disease of a newborn.
Term
vitamin K sie effects
Definition
hypotension,flushing, dizziness,scleroderma,abnormal taste, dyspnea
Term
Vitamin K mechanism of action
Definition
promotes live synthesis of clotting factors II,VII,IX,X,however the exact mechanism is unknown
Term
vitamin K
Definition
this drug may diminish the anticoagulant effect of coumadin dervatives
Term

cardizem drug class

Definition
calcium channel blocker
Term
cardizem use
Definition
hypertension, chronic stable angina from oronary artery spasm,atrial fibrillation or atrial ltter,supraventricular tachycardia
Term
cardizem side effects
Definition
edaem, headache, bradycardia, hypotension, vasodiltion, flushing, dizziness,nervousness, rash, constipation, vomiting, diarrhea
Term
cardizem dental implications
Definition
xerostomia,dysgeusia, gingival enlargement
Term
cardizem route of administration
Definition
IV, oral
Term
lipitor drug class
Definition
antilipemic agent
Term
lipitor use
Definition
treatment of abnormal lipids, or primary prevention of cardiovascular disease
Term
lipitor action
Definition
reduces production of mevalonic acid
Term
lipitor side effects
Definition
headache, dizziness, abdominal pain
Term
lipitor route of administration
Definition
oral
Term
triamterene (HCTZ) drug class
Definition
potassium-sparing diuretic
Term
triamterene another name
Definition
diazide (HCTZ)
Term
triamterene ( diazide) use
Definition
alone or in combination wih other diuretics in treatment of edema and hyertension, decrease potassium excreation caused by kaliuretic diuretics
Term
diazide (triamterene) action
Definition
interferes with potassium/soium exchange in the distal tubue, cortical collecting tubule and collecting duct by inhibiting sodium, potassium-ATPhse,decrease calcium excretion, increase magnesium loss
Term
diazide (triamterene) adverse reaction
Definition
hypotension, edema, CF,bradycardia, dizziness, headache, fatique constipation, nausea, dyspnea
Term
compazine (prochlorperazine) drug class
Definition
antiemitic, antipsychotic agent
Term
compazine (prochlorperazine) use
Definition
management of nausea and vomiting, psychotic disorders including schizophrenia
Term
compazine action
Definition
blocks dopaminergic receptors in the brain
Term
compazine adverse reactions
Definition
cardiac arrest, hypotension, peripheral edema. impairment of temperature, lwer than normal white blood cell count,excessive sweating
Term
compazine oral/dental considerations
Definition
xerostomia, orthostatic hypotension, tardive dyskinesia
Term
glucotrol (glipizide) drug class
Definition
antidiabetic agent
Term
hypoglycemic agent
Definition
lowers blood glucose
Term
glucotrol (glipizide) action
Definition
includes stimulation of the release of insulin from the cells of the pancreas, reduction of glucose from the liver, reduction of seru glucagon levels, and increasing the sensitivity of the target tissues to insulin, thereby lowering blood glucose levels.
Term
glucotrol (glipizide) use
Definition
treatment of NIDDM type II, who cannot be treated with diet and exercise alone and/or unable or willng to take insulin. Most often used in patients who are 50 or more in age. It is adjunct to diet for the control of hyperglycemia and its associated symptomatology. First line of treatment for Type II diabetes when used individually.
Term
glucotrol (glipizide) adverse reactions
Definition
blood dyscrasias, gastrointestional disturbances, cutaneous reactions, and liver damage.
Term
glucotrol (glipizide) drug interactions
Definition
aspirin causes a decrease in serum glucose levels not clinically significant unless patient is a brittle diabetic.
Term
glucotrol (glipizide) route of administration
Definition
oral
Term
generic name: zolpidem
Definition
brand name: ambien
Term
zolpidem drug class
Definition
ambiem: sedative or hypnotics
Term
zolpidem is clsely related to a family of sedatives called
Definition
benzodiazepines
Term
zolpidem (ambiem)
Definition
these drugs cause sedation, muscle relaxation, act as anti-convulsants (anti-seizure) and reduce anxiety.
Term
zolpidem (ambiem) use
Definition
sleeping pill to treat insomnia
Term
zolpidem (ambiem) drug interactions
Definition
alcohol has an additive effect. Should be used cautiously in patients with respiratory disease because of its depressing effect on breathing.
Term
zolpidem (ambiem) side effects
Definition
drowsiness, dizziness, and a drugged feeling, confusion, isomnia, euphoria, ataxia(balance problems) and visual changes.
Term
atrovent other name
Definition
ipratropium
Term
atrovent (ipratropium) drug class
Definition
anticholineric, broncodilator
Term
atrovent (ipratropium) administration
Definition
inhaled
Term
atrovent (ipratropium) side effects
Definition
xerostomia, bad taste
Term
atrovent (ipratropium) uses
Definition
drug of choice for long term management of COPD, patients with poorly controlled asthma or those who do not tolerate the side effects of the B agonists
Term
atrovent (ipratropium) drug interactions
Definition
bronchodilating effct is additive with that of the B agonists.
Term
meclizine (bonine) drug class
Definition
antiemetic: antihistamine
Term
meclizine (bonine) use
Definition
prevention & treatment of symptoms of motion sickness:management of vertigo wih disease affecting the vestibular system
Term
meclizine (bonine) effects on dental treatment
Definition
slight to moderate drowsiness, thickening of the bronchial secreations, signifiant xerostomia
Term
meclizine (bonine) adverse effects
Definition
slight to moderate drowsiness, thickening of bronchial secretions, heachache, fatigue, nervousness, dizziness, increased appetite and weight gain, abdominal pain, xerostomia
Term
meclizine (bonine) action
Definition
has cental anticholinergic action by blocking chemoreceptor tigger zone, decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular cerebellar pathways
Term
secretion of meclizine (bonine)
Definition
urine
Term
atenolol also know as
Definition
tenormin
Term
atenolol (tenormin) use
Definition
treatment of angina pectoris
Term
atenolol (tenormin) drug class
Definition
B-adrenergic blocking agent (selective beta blocker)
Term
atenolol (tenormin) action
Definition
block the B response to catecholamine stimulation, thereb reducing both the chronotropic and inotropic effects. The net result is reduced myocardial oxygen demand.
Term
atenolol (tenormin) adverse reactions
Definition
bradycardia,CHF,Headache, dry mouth, blurred vision, unpleasant dreams
Term
hyrochlorothiazide (hctz) drug class
Definition
diurectic agent
Term

hctz use

Definition
treatment of hypertension
Term
hctz side effects
Definition
hypokalemia & hyperuricemia(inhibits uric acid secretion) hyperglycemia, hyperlipidemia, hypercalcemia (promotes calcium reabsorption) anorexia
Term
Hctz drug interactions
Definition
interacts with the nonsteroid anti-inflammatory agents. They reduce the antihypertensive effects of the thiazide diuretics. This takes a few days to occur so few doses of NSAIA's can be safely taken for acute ain control.
Term

thiazide

Definition
most common diuretic
Term
diphenhydramine aslo know as
Definition
benadryl
Term
benadryl
Definition
antihistamine that causes drowiness
Term
benadryl use
Definition
used to treat allergic reactions
Term
benadryl uses
Definition
used with epinephrine in severe allergic reactions or anaphylaxis
Term
benadryl use
Definition
can be used as an antiemetic, can be used as a local anesthesia
Term
benadryl side effects
Definition
can cause xerostomia
Term
benadryl drug class
Definition
H1 receptor antagonists (blocker)
Term
metformin (glucophage) drug class
Definition
antidiebetic agent
Term
metformin (glucophage)
Definition
memeber of the biguanide group, lowers blood glucose, but used alone does not produce hyperglycemia
Term
metformin (glucophage) action
Definition
inhibits the production of glcose from the liver by educing hepatic gluconeogenesis
Term
metformin (glucophage) action
Definition
stimulation of glycolysis, slowing of glucose absorption from the gastrointestinal tract
Term
metformin (glucophage) action
Definition
reduction of plasma glucagons levels
Term
metformin (glucophage) adverse reactions
Definition
primarily related to gastrointestinal tract and include anorexia, dyspepsia, flatulence, nausea and vomiting
Term
metformin (glucophage) adverse reactions
Definition
can produce headache, and interfere with B12 absorption
Term
metformin (glucophage) adverse reactions
Definition
it accumulates in renal & hepatic impairment
Term
metformin (glucophage) adverse reaction
Definition
lactic acidosis is the most seriou side effect.Predisposing factors are alcoholism,binge rinking, and renal or hepatic dysfunction
Term
metformin (glucophage) side effects
Definition
oral manifestations include a metalic taste.
Term
omeprazole brand name
Definition
prilosec
Term
omeprazole (prilosec) drug class
Definition

proton pump imhibitor

Term
omeprazole (prilosec) use
Definition
potent inhibitor of gastric acid secretion (in combination with antibiotics) is effective in healing gastric and duodenal ulcers and is now approved for gerd
Term
omeprazole (prilosec) action
Definition
inhibition of the K/K ATPhase enzyme system at the surface of the gastric parietal cell and is called gastric acid (proton) pump inhibitor.
Term
omeprazole (prilosec) side effect
Definition
headache and abdominal pain
Term
zyban (bupropion) drug class
Definition
antidepressant, dopamine reuptake inhibitor, smoking cessation aid
Term
zyban also know as
Definition
bupropion
Term
zyban effects on dental treatment
Definition
abnormal taste,xerostomia
Term
bupropion action
Definition
weak inhibitor of the neuronal uptake of serotonin,norepinephrine,& dopamineand does not inhibit monoamine oxidase.
Term
coumadin also know as
Definition
warfarin
Term
coumadin drug class
Definition
anticoagulant, coumarin derivative
Term
coumadin use
Definition
prophylaxis and treatment of venous thrombosis, pulmonary embolism, atrial fibrillation with risk of embolism and as an adjunct in prophylaxis of systemic embolism after MI.
Term
coumadin effects on dentistry
Definition
bleeding from gingival tissue
Term
coumadin side effects
Definition
bleeding is a major side effect, edema, rash, vomiting
Term
coumadin action
Definition
interferes with hepatic synthesis of vitamin K-dependent coagulation factors (2,7,9,10)
Term
coumadin contraindicaions
Definition
hypersensensitivity, hemorragic tendencies, hemophilia
Term
coumadin drug interactions
Definition

increase effect-

acetaminophin,antifungals,cephalosporins,NSAIDS

,vitamin A& E

decreased- barbiturates,hormaonal contraceptives

Term
cetirizine also know as
Definition
zyretec
Term
cetirizine drug class
Definition
antihistamine
Term
cetirizine effects on dental treatment
Definition
xerostomia, stomatitis, loss of taste, abnormal taste, tongue discoloration, and ulcerative stomatitis
Term
cetirzine use
Definition
peripheral (nonsedating) antihistamine have some valuable adjuncts in the therapy of seaonal and perennial rhinitis
Term
cetirizine side effects
Definition

sedation,potentiation of opioids,reduced nausea, fatigue, headache, abdominal pain, bronchospasm

used for side effects as well as the antihistimine effect

Term
cetirizine mech of action
Definition
competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract
Term
amitriptyline also know as
Definition
elavil
Term
amitriptyline dental use
Definition
management of chronic neuropathic pain in TMD
Term
amitriptyline use
Definition
relief of symptoms of depression, unlabeled use - prophylaxis against migraine headache
Term
amitrityline effects on dental treatment
Definition
xerostomia and changes in salivation, orthostatic hypotension
Term
amitriptyline adverse effects
Definition
tachycardia, MI,stroke, syncope, nausea, stomatitis, peculiar taste, black tongue
Term
amitriptyline (elavil) mech of action
Definition
increases synaptic concentration of serotin and/or norepinephrine in the cns by inhibition of their reuptake
Term
digoxin also know as
Definition
lanoxin
Term
digoxin drug class
Definition
antiarrythmic
Term
digoxin use
Definition
treatment of CHF and to slow the ventricular rate intachyarrhythmias such as atrial fibrilation, atrial flutter, and supraventricular tachycardia, cardiogenic shock
Term
digoxin (lanoxin) effects on dental treatment
Definition
sensitive gag reflex,  may cause difficulty i taking dental impression
Term
digoxin (lanoxin) adverse reactions
Definition
asystole, antiety, confusion, nausea, vomiting
Term
digoxin( lanoxin) mech action
Definition
CHF inhibition of sodium/potassium ATPhase pump whih acts to increase the intracellular sodium/calcium exchange to increase intracellular calcium leading to increased contractilty
Term
digoxin (lanoxin) mech of action
Definition
supraventriclar arrythmias- direc suppression of the AV node conduction to increase effective refactory period and decrease conduction velocity
Term
digoxin (lanoxin) dietary considerations
Definition
maintain adequate amounts of potassium in diet to decrease risk of hypokalemia. Hyokalemia may increase risk of digoxin toxicity
Term
furosemide also know as
Definition
lasix
Term
furosemide drug class
Definition
loop diuretic
Term
furosemide mech of action
Definition
acts on the loop of henle to inhibit the reabsorption of chloride and sodium with resultant diuresis
Term
furosemide uses
Definition
pulmonary edema, edema in CHF, liver disease, nephritis syndromw, ascites, hypertenson with CHF when rapid diuresis is required
Term
furosemide side effects
Definition
xerostomia, hypokalemia,headache,fatigue,hyperuricemia,orthostatic hypotension,chest pain
Term
furosemide (lasix) precautions
Definition
diabetes mellitus, dehydration,several renal diseases, pregnancy
Term
furosemide (laxis) drug interactions
Definition
increased electrolyte imbalance,cortosteroids,decreased antihypertensive effects
Term
furosemide (laxis) dentl considerations
Definition
monitor vital signs, assess salivary flow, situpright for 2 minutes after supine position
Term
sertraline (zoloft) drug class
Definition
antidepressant
Term
sertraline also know as
Definition
zoloft
Term
sertraline use
Definition
treatment of major depression, obsessive compulsive disorder, panic disorder, post-traumatic stress disorder, premenstral dysphoric disorder, asocial anxiety disorder
Term
sertraline mech of action
Definition
antidepressant with selestive inhibitory effects on presynaptic serotonin reuptake and only very weak effects on norepinephrine and dopamine neuronal uptake
Term
sertraline adverse ractions
Definition

cns,

insomnia,somnolence,dizziness,

headache,fatigue,xerostomia,diarrhea,nausea

agitation,anxiety,nervousness

Term
sertraline dental considerations
Definition
induced bruxium
Term
chlorpromazine also know as
Definition
thorazine
Term
thorazine drug class
Definition
antipsychotic agent
Term
thorazine use
Definition
control of mania,treatment of schizophrenia,control of nausea & vomiting, relief of restlessness after surgery
Term
thorazine mech of action
Definition
blocks postsynaptic mesolimbic dopaminergic receptors in the brain
Term
thorazine mech of ation
Definition
exhibits a strong alpha-adrenergic blocking effect & depresses the release of hypothalamic & hypophyseal hormones
Term
thorazine adverse reactions
Definition
sedation, acute dystonia, parkinson like symptoms, tardive dyskinesia, seizures, xerostomia
Term
thorazine drug interactions
Definition
cns depressant including barbiturates, alcohol, general anesthetics, and opioid analgesics
Term
thorazine dental considerations
Definition
xerostomia, orthostatic hypotension, TMJ pain
Term
K-Dur drug class
Definition
potassium electrolyte
Term
k-dur use
Definition
aids in prevention and treatment of hypokalemia
Term
k-dur adverse reactions
Definition
gastrointestional tract & nausea and abdominal discomfort caused by gastointestional irritation
Term
k -dur mech of action
Definition
needed for adequate transmission of nerve impulses and cardiac contraction,renal function, and intracellular function
Term
k-dur drug interactions
Definition
decreased potassium & requirement, cortisteroids,increased gi side effects with nticholinergic drugs & nsaids
Term

k-dur excreted by

Definition
the kidneys in feces
Term
k-dur also know as
Definition
potassium chloride
Term
albuterol drug class
Definition
B2 agonist, bronchodilator
Term
albuterol use
Definition
the first line of treatment for mild or occasional asthma,emergency treatmen of acute attack of asthma
Term
albuterol side effects
Definition
tachycardia,xerostomia
Term
buspar also known as
Definition
busiprone
Term
buspar drug class
Definition
anxiolytic group,muscle relaxant
Term
buspar mech of action
Definition
unknown, but belived to be related to interactions with neurotransmitters in the cns(serotonin,dopamine,cholinergic,& alph adrenergic
Term
buspar phar effects
Definition
called anxioselective because of its elective anxiolytic action without hypnotic,anticonvulsant or muscle relaxant properties
Term
buspar adverse effects
Definition
low cns depression
Term
buspar
Definition
does not affect driving ability,does not produce tolerance or dependence, is not addicting and there is no withfrwl symptoms
Term
buspar drug class
Definition
antianxiety
Term
buspar use
Definition
management of generalized anxiety disorder
Term
midazolam also know as
Definition
versed
Term
versed drug class
Definition
benzodiazepine
Term
versed use
Definition
preoperative sedation
Term
midazolam adverse reactions
Definition
hypotension,drowiness,headache,nausea,vomiting
Term
midazolam use
Definition
parenterally to treat tonic-clonic seizures or status epilepicus
Term
divalproex also known as
Definition
depakote
Term
depakote drug class
Definition
anticonvulsant
Term
depakote mech of action
Definition
has effect on sodium or potassium channels, reduction in apartate levels, increase in GABA
Term
divalproex sodium adverse reactions
Definition
indigestion, nausea, vomiting most common, hypersalivation not as common, sedation,drowiness,bleeding, increasein birth defects
Term
divalproex sodium drug interactions
Definition
use with caution when aking other drugs that cause bleeding, other cns depressant drugs can have additive effect, increase action of phenytoin when taking with this drug
Term
phenytoin also known as
Definition
dilantin
Term
dilantin use
Definition
to treat tonic-clonic and partial seizure, trigemial neuralia
Term
phenytoin drug class
Definition
anticonvulsant and antiarrythmic properties
Term
phenytoin adverse reactions
Definition
mental confusion,slurred speach, reactions associated with elevated blood levels, can cause vitamin deficiency(D & folate) resulting in oral mucosa changes gingival enlargement
Term
tegretol also known as
Definition
carbamazepine
Term
carbamazepine drug class
Definition
anticonvulsant
Term
tegretol use
Definition
anticonvulsant, anticholinergic,antidepressant,sedative, muscle relaxant
Term
carbamazepine mech of action
Definition
invoves blocking sodium channels which blocks the propagation of nerve impulses
Term
tegretol adverse reactions
Definition
cns depression and gi tract problems,petechie o signs of infection,chf,
Term
tegretol drug interactions
Definition
reduced doxycycline effect and erythromycin increased carbamazepine
Term
provera also known as
Definition
medroxyprogesterone
Term
provera drug class
Definition
estrogen progestin combination
Term
provera mech of action
Definition
inhibits secretion of pituitary gonadotropins,prevents follicular maturation and ovulation
Term
provera use
Definition
uterine bleeding, secondary amenorrhea,endometrial cancer,prevents the risk of uterine cancer
Term
medroxyprogesterone side effects
Definition
gingival bleeding, gingival overgrowth,dizziness,bloating, breakthrough bleeding,acne
Term
provera contraindications
Definition
breast cancer,hypersensitivity,thromboembolic disorders
Term
provera precautions
Definition
lactation,hypertension,asthma,gallbladder disease,chf,diabetes mellitus
Term
hctz
Definition
has side effects that resemble lichens planus
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