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Figures out Rates (CHANGE in rate) |
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critical determinants for drug performance |
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Definition
– Physicochemical characteristics of active pharmaceutical ingredient (API) – Dosage form of the drug – Route of administration |
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science examining -in vivo/vitro methodologies -RoA -Dosage - Physiochemical property of API (drug) |
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Relationship between initial drug conc. vs drug conc. after reaching target site (metabolism and excretion)
Involves experimental and theoretical |
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Pharmakinetics vs Pharmadynamics |
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Definition
ADME vs Receptor binding and effect |
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Relationship between drug conc. @ site of action and response. |
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