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Details

Pharm -- MSK
First Aid 2012 pp429-432
23
Medical
Graduate
02/07/2013

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Cards

Term
naproxen
Definition
NSAID
Term
indomethacin
Definition
NSAID
Term
ketorolac
Definition
NSAID
Term
diclofen
Definition
NSAID
Term
fenoprofen
Definition
NSAID
Term
piroxicane
Definition
NSAID
Term
random NSAID side effect
Definition
fluid retention
Term
celecoxib
Definition
selective COX-2 inhibitor
Term
acetaminophen
Definition
COX inhibitor in CNS!!!
Term
do NSAIDs inhibit platelets like ASA?
Definition
no! because they're reversible (TxA2 can accumulate still?)
Term
is acetoaminophen anti-inflammatory
Definition
no! just antipretic and analgesic b/c only in CNS!!
Term
-dronate
Definition
bisphosphonates
analogue of pyrophosphate (component of hydroxyapatite) --> decrease formation of hydroxyapatite
inhibits osteoclastic activity and increase osteoclast death --> decreased resorption of hydroxyapatite
Term
side effects of topical steroids
Definition
atrophy of dermis, los of collagen, drying, cracking, tightening of skin, telangiectasias, ecchymosis
Term
probenecid
Definition
inhibits reabsorption of uric acid in PCT (and secretion of penicillin!!)
Term
febuxostat
Definition
XO inhibitor
Term
colchicine
Definition
binds tubulin and inhibits polymerization --> inhibit WBC chemotaxis and degranulation
diarrhea!!!
Term
etancercept
Definition
recombinant form of TNF receptor (decoy!!)
Term
infliximab
Definition
anti-TNF antibody
Term
adalimumab
Definition
anti-TNF antibody
Term
sunscreens
PABA, avobenone, zinc oxide
Definition
UVB only
UVAI and UVAII
UVAI, UVAII, and UVB!!
Term
calcipotriene
Definition
topical vit D analog --> activates nuclear transcription factor --> inhibits keratinocyte proliferation and stim keratinocyte differentiation (for psoriasis)
Term
calcitriol
Definition
topical vit D analog --> activates nuclear transcription factor --> inhibits keratinocyte proliferation and stim keratinocyte differentiation (for psoriasis)
Term
tacalcitol
Definition
topical vit D analog --> activates nuclear transcription factor --> inhibits keratinocyte proliferation and stim keratinocyte differentiation (for psoriasis)
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